Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Galectin Therapeutics to initiate GM-CT-01 Phase 1/2 combination study in advanced MM

Galectin Therapeutics, the Cancer Centre at the Cliniques universitaires Saint-Luc and the Ludwig Institute for Cancer Research (LICR) announced today that they will initiate a Phase 1/2 safety and efficacy trial testing a novel treatment combination in patients with advanced metastatic melanoma.

9 Dec 2011

Treating 'brain tsunamis' could stop many victims of major head injury from further damage

Treating 'brain tsunamis' or 'killer waves' could stop many victims of major head injury from suffering additional brain damage, a study published in Lancet Neurology has found.

8 Dec 2011

BCX4945 proves effective at clearing malaria infections

An antimalarial agent developed by researchers at Albert Einstein College of Medicine of Yeshiva University proved effective at clearing infections caused by the malaria parasite most lethal to humans - by literally starving the parasites to death. The novel research, carried out on a small number of non-human primates, could bolster efforts to develop more potent therapies against one of the world's leading killers.

8 Dec 2011

Fatty livers burn more fat, not less

When our livers become loaded with fat, it isn't because they are slacking. A new study of human patients in the December Cell Metabolism shows that fatty livers actually burn more fat, not less. All that "hard work" may be at the root of the organ damage that comes with nonalcoholic fatty liver disease (NAFLD), a condition associated with insulin resistance that affects about one in three in the U.S. population.

6 Dec 2011

Study evaluates whether genetic GST polymorphisms increase risk of ALD in alcoholics

It has been widely observed that only a small percentage of alcoholics develop cirrhosis of the liver, the most advanced form of alcoholic liver disease (ALD); the reason why all alcoholics do not develop such disease is not known. The present study from Spain, that includes original work and a meta-analysis, evaluates whether genetic polymorphisms that determine levels of glutathione-S-transferases (GST) relate to the risk of developing ALD among alcoholics.

6 Dec 2011

Albert Einstein College of Medicine and Montefiore establish Office of Clinical trials

Montefiore Medical Center and Albert Einstein College of Medicine of Yeshiva University have established an Office of Clinical Trials (OCT) to bring new therapies more rapidly to patients through the facilitation of efficient, compliant and timely conduct and management of clinical studies.

6 Dec 2011

Endocrine Society supports policies that aim to combat pediatric obesity

Today, The Endocrine Society issued a Position Statement supporting policies that bring together doctors and other healthcare providers, family, schools and the community to combat pediatric obesity through education and encouragement of lifestyle modifications.

6 Dec 2011

Alcohol related liver problems on the rise among the young

According to the NHS figures there has been a huge increase in the number of young adults treated in hospital for serious liver problems brought on by drinking too much.

5 Dec 2011

Factors associated with increased risk of in-hospital falls after total hip or knee replacement surgery

Investigators from Hospital for Special Surgery have identified factors that are associated with an increased risk of in-hospital falls after total hip or knee replacement surgery.

5 Dec 2011

New technique allows production of medically useful amounts of endoderm cells from human PSCs

Scientists in Canada have overcome a key research hurdle to developing regenerative treatments for diabetes and liver disease with a technique to produce medically useful amounts of endoderm cells from human pluripotent stem cells. The research, published in Biotechnology and Bioengineering, can be transferred to other areas of stem cell research helping scientists to navigate the route to clinical use known as the 'valley of death'.

3 Dec 2011

Baby boomers more likely to develop HCV

Experts at Montefiore Medical Center urge the general public to be tested for the Hepatitis C virus, especially baby boomers, adults born between 1946-1964, who could be most at risk for this disease. Baby boomers are more likely to have been exposed to dangerous risk factors decades ago, such as sharing a drug needle, being tattooed or pierced with unsterilized tools or receiving a tainted blood transfusion.

2 Dec 2011

Bristol-Myers Squibb, Tibotec partner for TMC435 Phase II combination study in HCV

Medivir AB, the research-based speciality pharmaceutical company focused on the development of high-value treatments for infectious diseases, announces that its development partner, Tibotec Pharmaceuticals, has entered into an agreement with Bristol-Myers Squibb Company.

2 Dec 2011

Einstein, Montefiore receive NINDS grant to establish clinical site for NeuroNEXT

In a development that could pave the way for treatment for rare neurological diseases and clues to more common ones, physician-scientists at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center, the University Hospital for Einstein, have secured a grant to establish a clinical site for the Network for Excellence in Neuroscience Clinical Trials.

2 Dec 2011

EGCG may prevent HCV reinfection after liver transplantation

German researchers have determined that epigallocatechin-3-gallate (EGCG)—a flavonoid found in green tea—inhibits the hepatitis C virus (HCV) from entering liver cells.

1 Dec 2011

Elevated blood sugar levels linked with increased risk of colorectal cancer

Elevated blood sugar levels are associated with an increased risk of colorectal cancer, according to a study led by researchers at Albert Einstein College of Medicine of Yeshiva University.

30 Nov 2011

Repeated heading of a soccer ball increases risk for brain injury, cognitive impairment

Using advanced imaging techniques and cognitive tests, researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center , the University Hospital and academic medical center for Einstein, have shown that repeatedly heading a soccer ball increases the risk for brain injury and cognitive impairment.

29 Nov 2011

Serotonin instructs scar forming cells to switch off regeneration in chronic liver disease

In liver disease, extent of tissue damage depends on the balance between the generation of scar tissue and the regeneration of new liver cells. In a significant minority of people who get injury to their organs instead of repairing them, they form scars.

29 Nov 2011

Einstein, Montefiore experts available to discuss effects of radiation dose and exposure

Experts from Montefiore Medical Center and Albert Einstein College of Medicine of Yeshiva University are available for interviews on topics ranging from effects of radiation dose and exposure to MRI imaging to detect brain damage in soccer players due to "heading" and cancer post-treatment imaging during the annual Radiological Society of North America Scientific Assembly.

24 Nov 2011

Non-alcoholic fatty liver disease does not appear to affect survival

Non-alcoholic fatty liver disease (NAFLD) is a common condition associated with obesity and heart disease long thought to undermine health and longevity. But a new study by Johns Hopkins researchers suggests the condition does not affect survival.

22 Nov 2011

Researchers manipulate life span of yeast by mutating chemical residues

Collaborations between Johns Hopkins and National Taiwan University researchers have successfully manipulated the life span of common, single-celled yeast organisms by figuring out how to remove and restore protein functions related to yeast aging.

22 Nov 2011

Liver Disease News and Research

Further Reading

Galectin Therapeutics to initiate GM-CT-01 Phase 1/2 combination study in advanced MM

Treating 'brain tsunamis' could stop many victims of major head injury from further damage

BCX4945 proves effective at clearing malaria infections

Fatty livers burn more fat, not less

Study evaluates whether genetic GST polymorphisms increase risk of ALD in alcoholics

Albert Einstein College of Medicine and Montefiore establish Office of Clinical trials

Endocrine Society supports policies that aim to combat pediatric obesity

Alcohol related liver problems on the rise among the young

Factors associated with increased risk of in-hospital falls after total hip or knee replacement surgery

New technique allows production of medically useful amounts of endoderm cells from human PSCs

Baby boomers more likely to develop HCV

Bristol-Myers Squibb, Tibotec partner for TMC435 Phase II combination study in HCV

Einstein, Montefiore receive NINDS grant to establish clinical site for NeuroNEXT

EGCG may prevent HCV reinfection after liver transplantation

Elevated blood sugar levels linked with increased risk of colorectal cancer

Repeated heading of a soccer ball increases risk for brain injury, cognitive impairment

Serotonin instructs scar forming cells to switch off regeneration in chronic liver disease

Einstein, Montefiore experts available to discuss effects of radiation dose and exposure

Non-alcoholic fatty liver disease does not appear to affect survival

Researchers manipulate life span of yeast by mutating chemical residues

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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