Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Extended liver preservation technique shows promise for daytime transplants

Phase II clinical trial evaluates the safety and feasibility of prolonged DHOPE for extending human donor liver preservation to 20 hours, showing potential for facilitating daytime liver transplantation.

11 Jan 2024

New imaging technique could transform diagnosis and treatment of steatotic liver disease

Steatotic liver disease (SLD), previously known as non-alcoholic fatty liver disease, which includes a range of conditions caused by fat build-up in the liver due to abnormal lipid metabolism, affects about 25% of the population worldwide, making it the most common liver disorder.

9 Jan 2024

£30M clinical study will enhance the understanding of NASH cirrhosis

The most extensive clinical study into liver cirrhosis ever conducted worldwide has been announced by Newcastle University, University of Edinburgh and leading research-driven global biopharmaceutical company, Boehringer Ingelheim.

8 Jan 2024

Revolutionary study reveals Lactobacillus acidophilus could ward off liver cancer linked to fatty liver disease

Probiotic supplementation with Lactobacillus acidophilus could help prevent non-alcoholic fatty liver disease.

8 Jan 2024

Combining ezetimibe and bempedoic acid effectively lowers cholesterol in statin-intolerant patients

A simulation study analyzing over two million German outpatients found that combining ezetimibe and bempedoic acid effectively reduces LDL cholesterol in statin-intolerant patients with hypercholesterolemia.

7 Jan 2024

New app helps patients with alcohol-related liver disease recover, saves lives

A mobile phone app which helps patients with alcohol-related liver disease to stay sober could help save hundreds of lives every year, according to researchers from UCL and the Royal Free Hospital who developed the app.

5 Jan 2024

Gut microbes revealed as key players in liver disease solutions

In the editorial published on 4 September 2023, in the "gut-liver axis" special issue of the journal Hepatobiliary & Pancreatic Diseases International, Dr. Jian-Gao Fan and Dr. Lu Jiang from Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine provided a comprehensive elucidation of the pivotal role of gut microbiota in various liver diseases.

4 Jan 2024

CLivD score shows promise in early detection of steatotic liver disease and advanced fibrosis

Chronic liver disease, a growing threat to global health, often progresses silently in its early stages.

4 Jan 2024

Exploring the global health challenge of hepatitis D

Review explores the global impact of the hepatitis D virus (HDV) on public health, detailing its transmission, clinical course, diagnosis, and treatment options.

2 Jan 2024

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Very early in the COVID-19 pandemic clinical trials in patients hospitalized with COVID-19 confirmed that corticosteroids like dexamethasone reduced mortality, but they were harmful when applied at the first COVID-19 symptoms, due to the weakening of innate antiviral immunity, leading to delayed viral clearance and adverse outcomes in severe viral pneumonias.

28 Dec 2023

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Research pioneer Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named 2023 breakthrough of the year by the Science Magazine.

18 Dec 2023

Study shows synergistic effects of genetic factors, binge drinking, and diabetes in alcohol-related cirrhosis

Researchers investigated associations between alcohol consumption behaviors, diabetes mellitus, genetic predispositions, and ARLD incidence in 312,59 active drinkers from the United Kingdom Biobank.

18 Dec 2023

Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

Science has named the development of glucagon like peptide-1 (GLP-1) agonists and this year's discovery that these drugs can blunt obesity-associated health problems as its 2023 Breakthrough of The Year.

15 Dec 2023

Study points to binge drinking and genetics as key factors in liver disease

Those who binge drink and have a certain genetic makeup are six times more likely to develop alcohol-related cirrhosis, according to new research from UCL, the Royal Free Hospital, the University of Oxford and the University of Cambridge.

14 Dec 2023

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Study in the International Journal of Obesity reveals that BMAL1 deletion in mice protects against obesity and non-alcoholic fatty liver disease caused by a high-fat diet, highlighting its potential as a therapeutic target.

13 Dec 2023

Tirzepatide maintains weight loss and improves cardiometabolic health in SURMOUNT-4 trial

The current class of anti-obesity drugs is proving remarkably effective at removing excess pounds. However, a phase 3 randomized clinical trial led by researchers at Weill Cornell Medicine and NewYork-Presbyterian found that people who stopped taking the medication regained much of that weight within a year.

11 Dec 2023

Intestine epithelium-derived exosomes serve as novel mediator in regulating hepatic lipid metabolism

Non-alcoholic fatty liver disease (NAFLD), characterized by excessive hepatic lipid accumulation, poses a high prevalence and can progress to cirrhosis and liver cancer.

11 Dec 2023

Is there an association between meat and fish consumption and non-alcoholic fatty liver disease?

The associations between meat and fish consumption and the risk of non-alcoholic fatty liver disease (NAFLD).

11 Dec 2023

Machine learning reveals key markers for healthy aging, separate from chronic disease risks

Using machine learning, researchers successfully distinguished factors of healthy aging from chronic disease risks by analyzing health data across various ages, finding key markers like neutrophil counts and alkaline phosphatase levels as early indicators of healthy aging.

10 Dec 2023

Study explores the intricate gut-brain-liver connection and its impact on health

Study reviews the gut-brain-liver axis, revealing the complex interplay between these organs in health and disease and the implications for therapeutic interventions, focusing on how gut microbiota affects liver and brain health.

10 Dec 2023

Liver Disease News and Research

Further Reading

Extended liver preservation technique shows promise for daytime transplants

New imaging technique could transform diagnosis and treatment of steatotic liver disease

£30M clinical study will enhance the understanding of NASH cirrhosis

Revolutionary study reveals Lactobacillus acidophilus could ward off liver cancer linked to fatty liver disease

Combining ezetimibe and bempedoic acid effectively lowers cholesterol in statin-intolerant patients

New app helps patients with alcohol-related liver disease recover, saves lives

Gut microbes revealed as key players in liver disease solutions

CLivD score shows promise in early detection of steatotic liver disease and advanced fibrosis

Exploring the global health challenge of hepatitis D

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Study shows synergistic effects of genetic factors, binge drinking, and diabetes in alcohol-related cirrhosis

Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

Study points to binge drinking and genetics as key factors in liver disease

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Tirzepatide maintains weight loss and improves cardiometabolic health in SURMOUNT-4 trial

Intestine epithelium-derived exosomes serve as novel mediator in regulating hepatic lipid metabolism

Is there an association between meat and fish consumption and non-alcoholic fatty liver disease?

Machine learning reveals key markers for healthy aging, separate from chronic disease risks

Study explores the intricate gut-brain-liver connection and its impact on health

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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