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Study finds significant differences across hospitals providing care for children with medical complexity

Although children with high health care needs represent a small percentage of the overall pediatric population, they account for a large percentage of pediatric health care costs, including up to 40% of pediatric hospital charges. In recent years, there has been more information available about the medical care received by these children, but generally studies have been limited to care provided in hospital settings.

6 Oct 2015

Chromosome 3q26.2 rearrangements linked to poor CML prognosis

Rearrangements of chromosome 3q26.2 have a significant negative impact on patients with chronic myeloid leukaemia, suggests research published in Blood.

1 Oct 2015

Researchers identify new gene locus that may protect children from developing malaria in Africa

Published today in Nature, the findings detail a new gene locus that can explain why, in communities where everyone is constantly exposed to malaria, some children develop severe malaria and others don't. Now, researchers can be sure that this particular stretch of our DNA plays a crucial role in the progression of the disease.

1 Oct 2015

Brain cells in Parkinson's disease die prematurely, burning out like an overheating motor

The death of brain cells in Parkinson's disease may be caused by a form of cellular energy crisis in neurons that require unusually high quantities of energy to carry out their job of regulating movement, researchers at the University of Montreal reported today.

28 Aug 2015

Brief exposure to sudden sounds or mild trauma can form long-term memories

Researchers at NYU Langone Medical Center have found how even brief exposure to sudden sounds or mild trauma can form permanent, long-term brain connections, or memories, in a specific region of the brain. Moreover, the research team, working with rats, says it was able to chemically stimulate those biological pathways in the locus coeruleus -- the area of the brain best known for releasing the "fight or flight" hormone noradrenaline -- to heighten and improve the animals' hearing.

25 Aug 2015

Research: Critical aspects of human genome's regulatory program encoded by genomic sequence elements

Since the classical studies of Jacob and Monod in the early 1960s, it has been evident that genome sequences contain not only blueprints for genes and the proteins that they encode, but also the instructions for a coordinated regulatory program that governs when, where and to what extent these genes and proteins are expressed.

4 Aug 2015

Researchers discover gene locations affecting wrist bones in children

Pediatric researchers have discovered gene locations affecting bone strength in wrist bones, the most common site for fractures in children. Children who have those genetic variants may be at higher-than-average risk of wrist fractures, and could especially benefit from activities and diets that promote bone strength.

30 Jun 2015

Study reveals molecular basis for endocrine therapy-resistant breast cancer

Mitsuyoshi Nakao, Director of the Institute of Molecular Embryology and Genetics in Kumamoto University and Associate Professor Noriko Saitoh revealed that a cluster of defined, non-coding RNAs are mechanistically involved in endocrine therapy resistance in human breast cancer cells. Furthermore, resveratrol, a kind of polyphenol, was found to repress these RNAs and inhibit the proliferative activity of breast cancer cells which had acquired resistance.

27 May 2015

GTEx findings reveal how genomic variants can affect gene activity and disease susceptibility

Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and much-anticipated data resource to help establish how differences in an individual's genomic make-up can affect gene activity and contribute to disease.

8 May 2015

New health-focused code school coming to Chicago

The newest code school in Chicago, CodeAbode, starts classes on June 1. CodeAbode offers "boot camp" and part-time options designed to turn students into web and mobile app developers.

6 May 2015

Sangamo BioSciences to present data on ZFP Therapeutic platform at ASGCT meeting

Sangamo BioSciences, Inc. announced that data from clinical, preclinical and research-stage programs focused on the development of ZFP Therapeutics will be presented at the 18th Annual Meeting of the American Society of Gene and Cell Therapy

29 Apr 2015

Study paves way for greater understanding of Attention Deficit Hyperactivity Disorder

Researchers at the Angiocardioneurology Department of the Neuromed Scientific Institute for Research, Hospitalisation and Health Care of Pozzilli (Italy), have found, in animal models, that the absence of a certain enzyme causes a syndrome resembling the Attention Deficit Hyperactivity Disorder (ADHD).

16 Apr 2015

Study: Key signaling pathway in B-cell lymphoma can be blocked using compounds

Cancer researchers from the University of Zurich have identified a key signaling pathway in B-cell lymphoma, a malignant type of blood cancer.

7 Apr 2015

Genomics researchers discover novel gene variants in childhood CVID

Genomics researchers analyzing a rare, serious immunodeficiency disease in children have discovered links to a gene crucial to the body's defense against infections. The finding may represent an inviting target for drugs to treat common variable immunodeficiency (CVID).

27 Feb 2015

New study finds that wandering mind can impart distinct cognitive advantage

Does your mind wander when performing monotonous, repetitive tasks? Of course! But daydreaming involves more than just beating back boredom. In fact, according to a new study published in the Proceedings of the National Academy of Sciences, a wandering mind can impart a distinct cognitive advantage.

24 Feb 2015

Thync electrical neurosignaling reduces brain's response to stress, shows study

Thync today announced results from a study published via bioRxiv that show electrical neurosignaling delivered by its consumer wearable device reduces the brain's response to stress in a chemical-free manner.

13 Feb 2015

Newly found protein in naked mole rat helps ward off cancer

A protein newly found in the naked mole rat may help explain its unique ability to ward off cancer.

5 Feb 2015

CUMC researchers use innovative algorithm to find driving force behind aggressive form of glioblastoma

Using an innovative algorithm that analyzes gene regulatory and signaling networks, Columbia University Medical Center researchers have found that loss of a gene called KLHL9 is the driving force behind the most aggressive form of glioblastoma, the most common form of brain cancer.

10 Oct 2014

Chinese study of serogroup 6 S. pneumoniae finds no antibiotic-resistant clones

A survey of serogroup 6 Streptococcus pneumoniae isolates from children in China has identified no antibiotic-resistant clones, leading the authors to speculate that the isolates may be under antibiotic selective pressure.

8 Sep 2014

Study identifies novel gene that controls nerve conduction velocity linked with MS

A new study published in The American Journal of Pathology identifies a novel gene that controls nerve conduction velocity.

13 Aug 2014