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GPNMB established as a risk gene and potential therapeutic target for Parkinson's disease

Computational, cell biological, and human tissue-based studies establish GPNMB as a risk gene and potential therapeutic target for Parkinson's Disease (PD), researchers report.

18 Aug 2022

Researchers identify the brain circuity that controls social component of song learning in birds

In learning to communicate, a good teacher is essential. Take zebra finches, for example. Juveniles of the species learn songs directly from a tutor – usually their father – through a social interaction that keeps them motivated and on-task.

16 Aug 2022

Here's why thinking hard exhausts you

Researchers elucidate the neuro-metabolic mechanisms responsible for cognitive fatigue that occurs following extended and intense working hours.

15 Aug 2022

Scientists present highly accurate novel framework for SARS-CoV-2 genomic surveillance

Researchers presented a novel framework for SARS-CoV-2 genomic surveillance based on case studies from New York, the United States, and the United Kingdom in a new study.

10 Aug 2022

Research progress on the three-dimensional interaction between virus and host genome

A recent study reviewed the current progress on 3D interactions between host and viral genomes.

8 Aug 2022

How can we map the human genetic architecture of COVID-19 across all ancestry groups?

In a new study, researchers formed the COVID-19 host genetics initiative to compile a genome-wide association meta-analysis of 60 studies from 25 countries.

8 Aug 2022

New dual-plasmid editing system for DNA-based information rewriting in vivo

DNA-based information is a new interdisciplinary field linking information technology and biotechnology.

5 Aug 2022

Study sheds light on the pathogenic brain mechanisms associated with evolution of anxiety

Monoamine neurotransmitters such as serotonin and dopamine play important roles in our cognitive and emotional functions.

5 Aug 2022

Researchers propose a new statistical method for analyzing the genetic admixture of populations

Researchers of the HSE International Laboratory of Statistical and Computational Genomics together with their international colleagues have proposed a new statistical method for analysing population admixture that makes it possible to determine the time and number of migration waves more accurately.

27 Jul 2022

Temporal changes in CD4 T-lymphocyte dynamics upon immunization against SARS-CoV-2 spike protein

Researchers assessed changes in CD4 T-lymphocyte temporal dynamics by evaluating T-lymphocyte responses to SARS-CoV-2 S using Foxp3-Tocky mice and Nr4a3-Tocky mice.

27 Jul 2022

Researchers discover new chromosomal section effective against diseases in oats

Whether you opt for a crunchy granola bar, mushy bowl of oatmeal, or smooth glass of oat milk, it is clear oats are gaining popularity-;both with consumers and breeders. Oats provide a naturally gluten-free source of nutrition, with proven health benefits for humans and livestock.

21 Jul 2022

Influence of chr12q24.13 domain on COVID-19 severity

Researchers evaluated the probable impact of the chr12q24.13 domain on the outcomes of laboratory-validated SARS-CoV-2 infection.

19 Jul 2022

Scientists manipulate good bacteria using CRISPR systems

New North Carolina State University research shows progress in gathering information on an important – yet difficult to characterize – human gut bacterium called Bifidobacterium, which is used in many probiotics that help maintain healthy microbiomes.

19 Jul 2022

The impact of gene amplification in virus adaptation through intermediate hosts

Researchers assessed the impact of gene amplification on cross-species adaptation.

12 Jul 2022

A cancer patient who had SARS-CoV-2 for over eight months

In a recent study posted to the medRxiv* pre-print server, researchers in Israel described the case of a severely immunocompromised cancer patient who developed a chronic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

28 Jun 2022

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

In a recent article posted to the bioRxiv* preprint server, researchers at Texas Biomedical Research Institute, Georgia State University, and the University of Alabama at Birmingham developed a bireporter-expressing recombinant severe acute respiratory syndrome coronavirus 2 (rSARS-CoV-2) for tracking SARS-CoV-2 infection.

27 Jun 2022

New method helps unravel three-dimensional structure of the human genome

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional structure of the human genome, or how the genome folds.

23 Jun 2022

People who believe luck determines their fate are more likely to have severe gum disease

People who believe that luck or chance determine what happens to them are more likely to have severe gum disease compared with those who think their own actions are mainly responsible.

16 Jun 2022

Study sheds light on inhibition of awn elongation in sorghum

Over the years, the domestication of grasses like wheat, rice, barley, and sorghum for consumption has resulted in certain modifications to their morphology. One such modification is the partial or complete elimination of the 'awns', which are the bristle- or needle-like appendages extending from the tip of the lemma in grass spikelets.

15 Jun 2022

Sarbecovirus pathogenesis regulated by a multitrait locus

In a recent study posted to the bioRxiv* preprint server, the authors demonstrated that the sarbecovirus pathogenesis was regulated by a multitrait locus.

7 Jun 2022