Low Density Lipoprotein (LDL) News and Research

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Canada tackles growing obesity epidemic

The first-ever Canadian Clinical Practice Guidelines (CPG) on the Management and Prevention of Obesity in Adults and Children, published April 10, 2007 in the Canadian Medical Association Journal (CMAJ), recommend that waist circumference be measured in all Canadian adults, and that a national surveillance system be developed that incorporates this measurement along with height and weight.

10 Apr 2007

Smoke from other people's burning tobacco kills

The debate is over, according to a 2006 surgeon general's report on secondhand smoke.

5 Apr 2007

Raman spectroscopy for faster body-fluid tests

University of Rochester researchers announce in the current issue of Applied Optics a technique that in 60 seconds or less measures multiple chemicals in body fluids, using a laser, white light, and a reflective tube.

4 Apr 2007

Effect of Torcetrapib on the progression of coronary atherosclerosis

Investigators report that torcetrapib, a drug that substantially raises high-density lipoprotein cholesterol or HDL (the "good" cholesterol), did not slow the progression of plaque buildup in the coronary arteries as measured using an ultrasound probe (IVUS).

2 Apr 2007

Addition of torcetrapib to statin therapy has no benefit for atherosclerosis progression

For some patients with high cholesterol, even the most aggressive treatment with statin drugs fails to prevent coronary artery disease.

2 Apr 2007

Study results on bifeprunox in patients with schizophrenia

Solvay Pharmaceuticals, Inc., Wyeth Pharmaceuticals and Lundbeck A/S presented clinical study results on bifeprunox at an international medical congress this week.

2 Apr 2007

Higher trans fat levels in blood associated with elevated risk of heart disease

High consumption of trans fat, found mainly in partially hydrogenated vegetable oils and widely used by the food industry, has been linked to an increased risk of coronary heart disease (CHD).

30 Mar 2007

Pomegranate juice may help fight prostate cancer

Few American men have heard of the pomegranate, and fewer still have eaten this curious-looking fruit loaded with red seeds. But new scientific findings suggest that pomegranates may one day find a place in healthful diets, reports the April 2007 issue of Harvard Men's Health Watch.

28 Mar 2007

Study provides strongest link to date between trans fat and heart disease

High consumption of trans fat, found mainly in partially hydrogenated vegetable oils and widely used by the food industry, has been linked to an increased risk of coronary heart disease (CHD).

28 Mar 2007

Medications plus lifestyle changes work as well as angioplasty to reduce deaths in stable heart-disease patients

Coronary revascularization with stenting or balloon angioplasty combined with optimal medical therapy is no more effective in preventing a heart attack, other major cardiovascular events or death in patients with stable heart disease, than optimal medical therapy alone, results of a new study conducted in 50 hospitals in the U.S. and Canada has shown.

27 Mar 2007

Lipitor given the green light for more heart risk patients

The Food and Drug Administration (FDA) in the U.S. has given approval for the best seller drug Lipitor to be used in five new categories.

8 Mar 2007

Study compares Lipitor with Simvastatin

A retrospective analysis of a large U.S. managed care database showed that patients who took Pfizer's cholesterol-lowering medicine Lipitor (atorvastatin calcium) Tablets had a significant 14 percent reduction in the risk of cardiovascular events, including heart attacks and strokes, compared with patients who took simvastatin.

5 Mar 2007

Early life growth protects against "bad" cholesterol

Tall toddlers and rapidly growing teens are likely to find themselves with lower cholesterol, particularly the "bad" type, in later life, suggests research in the Journal of Epidemiology and Community Health.

4 Mar 2007

Garlic - a tasty addition to food but useless for lowering cholesterol

Researchers at Stanford University School of Medicine say they have found that eating garlic raw or taking it in supplement form does not lower "bad" cholesterol levels.

28 Feb 2007

Garlic does not lower LDL cholesterol

Three forms of garlic - including raw garlic and two types of commercial garlic supplements - did not significantly reduce low-density lipoprotein (LDL or "bad") cholesterol during a six-month trial, according to results published in the February 26 issue of Archives of Internal Medicine.

27 Feb 2007

Diet rich in black soya beans could help control weight, lower fat and cholesterol levels

Yellow soya has already been hailed for its cholesterol lowering capabilities; this is one of the reasons why frozen food manufacturer Birds Eye has added the beans to its range. However, a team of Korean researchers has shown that black soya may be even more potent in rats, and also prevents weight gain.

26 Feb 2007

Apolipoprotein C1 protein linked to elevated BMI in people of American Indian and Mexican ancestry

University of Minnesota researchers have discovered a variant of a common blood protein, apolipoprotein C1, in people of American Indian and Mexican ancestry that is linked to elevated body mass index (BMI), obesity and Type 2 diabetes.

22 Feb 2007

Health care professionals should focus on women's lifetime heart disease risk

The 2007 Guidelines for Preventing Cardiovascular Disease in Women -- published today in a special women's health issue of Circulation: Journal of the American Heart Association -- also include new directions for using aspirin, hormone therapy and vitamin and mineral supplements in heart disease and stroke prevention in women.

20 Feb 2007

An aspirin a day keeps heart disease away

According to new guidelines released by the American Heart Association, almost all women are at risk of heart disease and doctors should consider prescribing a daily aspirin for them.

20 Feb 2007

Updated guidelines provide definitive answers on HRT, aspirin, supplements

Health care professionals should focus on women's lifetime heart disease risk, not just short-term risk, according to updated American Heart Association guidelines.

20 Feb 2007