Low Density Lipoprotein (LDL) News and Research

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Actos reduces the combined risk of non-fatal heart attacks, strokes in patients with type-2 diabetes

A study published in The Lancet shows that Takeda's Actos (pioglitazone HCl), an oral glucose lowering medication, significantly reduces the combined risk of non-fatal heart attacks, strokes and deaths by an additional 16% on top of standard medication

10 Oct 2005

C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance

New research shows that levels of C-reactive protein (CRP), produced by the liver and not at the lesion site, correlate with the degree of atherosclerosis.

28 Sep 2005

Benefits of statin therapy identified

The greater the reduction in LDL (lower-density lipoprotein) cholesterol achieved by statin therapy the greater the reduction in incidence of major coronary events, coronary revascularisation and stroke, concludes a meta-analysis published online today by The Lancet.

27 Sep 2005

HDL cholesterol helps prevent blocked arteries and heart attack

Cardiology experts at Johns Hopkins have issued interim guidelines for physicians on how best to treat low levels of HDL cholesterol, the so-called good cholesterol, which helps keep arteries clear from the buildup of LDL cholesterol, the so-called bad cholesterol.

22 Sep 2005

News we always wanted to hear - Chocolate does you good!

In the best news yet for chocolate lovers, a new study has apparently shown that dark chocolate can lower blood pressure.

19 Jul 2005

Genes play an overriding role in cholesterol response

Why does it seem like some people can eat all the ice cream they want without increasing their cholesterol or gaining much weight, while others with high cholesterol have to watch their diets like a hawk? Because no matter what their lifestyle, people's genes play an overriding role in their cholesterol response.

11 Jul 2005

Genes decide the shape you're in!

According to a study by researchers at the Lawrence Berkeley National Laboratory of identical twins, the reason why some people can eat all the chocolate and chips they want and not increase their cholesterol levels, is all down to their genes.

11 Jul 2005

Fat in the bloodstream linked to heart attacks

New research, by Dr. Sotirios Tsimikas of the University of California, San Diego, has produced the first convincing evidence that a type of fat in the bloodstream can trigger the earliest conditions that lead to clogged blood vessels, the highest cause of heart attacks.

7 Jul 2005

Elevated C-reactive protein can foil diet's ability to lower cholesterol

If you have high levels of C-reactive protein (CRP), a marker in blood for inflammation that is strongly associated with heart disease, trying to lower your LDL-cholesterol through modest diet changes alone may not work.

20 Jun 2005

New study supporting the importance of aggressive cholesterol-lowering

New clinical data shows that intensive cholesterol-lowering to targets below currently recommended levels significantly reduces the risk of heart attack and stroke for people with diabetes and heart disease.

14 Jun 2005

Teen-age boys with type 1 diabetes showed evidence of greater atherosclerosis

Youths with type 1 diabetes, especially boys, already show early signs of cardiovascular disease by their teen-age years, according to researchers from the Keck School of Medicine of the University of Southern California and Childrens Hospital Los Angeles.

13 Jun 2005

Muraglitazar lowers blood glucose and helps dyslipidemia seen in diabetes

A novel compound provides long-term lowering of blood glucose levels and improves plasma lipids (fats) that are often a problem in people with type 2 diabetes -- all in a once-daily pill, according to a report presented today at the American Diabetes Association's 65th Annual Scientific Sessions.

12 Jun 2005

Study raises questions about food products meant to block cholesterol absorption

Plant sterols, which are naturally found in many foods but are also added to some foods intended to inhibit cholesterol absorption, are present in artery plaques, according to a new study (PDF) in the June 7, 2005, issue of the Journal of the American College of Cardiology.

9 Jun 2005

Novel targets found for the development of drugs to complement, or replace, statins

A team of investigators from the Uppsala Branch of the Ludwig Institute for Cancer Research (LICR) and Harvard Medical School has uncovered novel targets for the development of drugs that would potentially complement, or replace, statins in treating heart disease.

8 Jun 2005

Arena Pharmaceuticals issued new patent

Arena Pharmaceuticals has announced that it was issued U.S. patent number 6,902,902, entitled "Human G Protein-Coupled Receptors and Modulators Thereof for the Treatment of Metabolic-Related Disorders," by the U.S. Patent Office.

8 Jun 2005

Soy appears to lower cholesterol and blood sugar levels, aid weight loss

A quick trip through the health-food section of any grocery will reveal several labels touting soy content, but most Americans do not know much about soy beyond a vague idea that it is a healthy food.

8 Jun 2005

Alarming trends among steroid users

Major findings in a new survey of 500 steroid users reveal specific, alarming trends: most are non-athletes whose sole intention is to improve their physical appearance; users are taking larger doses than previously recorded; and even though nearly all admitted to adverse side effects, health concerns are not enough to deter their steroid use.

2 Jun 2005

You can teach your child to eat healthier

Parents, take heart: You can teach your child to eat healthier. A study of preadolescent children found that those who attended a behaviorally oriented nutrition education program and were taught to follow a diet low in saturated fat and dietary cholesterol adopted significantly better dietary habits over several years compared to their peers who received only general nutritional information.

1 Jun 2005

We have been ingrained to think that seriously large people can only make improvements in their health if they diet and slim down

Behavior change and self-acceptance trump dieting hands-down when it comes to achieving long-term health improvements in obese women, according to a two-year study by nutrition researchers at the University of California, Davis.

31 May 2005

Under prescribing of statins puts more people at risk of premature death

A new study out of Stanford School of Medicine says that cholesterol-lowering drugs known as statins that can help prevent heart disease are still underprescribed for many at-risk patients.

31 May 2005