Low Density Lipoprotein (LDL) News and Research

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Drug lowers inflammatory markers associated with risk for heart attack

A preliminary study suggests that use of a drug that inhibits a specific protein in patients with certain genetic variants that increase their risk for heart attack reduced their levels of inflammatory markers associated with heart attack risk, according to a study in the May 11 issue of JAMA.

10 May 2005

When it comes to low fat diets - all are not equal!

New research from the Stanford University School of Medicine re-enforces what Mum always told you, eat those veggies and those other nutrient-dense foods because they're good for you!

2 May 2005

Severely obese children have lipoprotein profiles that signal early risk of cardiovascular disease and the metabolic syndrome

"The message is urgent about the importance of prevention of cardiovascular disease in childhood. Lifestyle modification with appropriate diet and exercise can reduce cardiovascular risk in children," said lead author Daniel L. Preud'Homme, M.D., associate professor of medicine at the Wright State University School of Medicine and director of the lipid clinic at The Children's Medical Center, both in Dayton, Ohio.

1 May 2005

Fiber supplements may lower cardiovascular risk in type 2 diabetics

Fiber supplements lower "bad" low-density lipoprotein (LDL) cholesterol and increase "good" high-density lipoprotein (HDL) cholesterol in people with type 2 diabetes, according to a study presented at the American Heart Association's Sixth Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology.

1 May 2005

New statin study shows arrested progression of atherosclerosis

The first study to use cutting edge magnetic resonance imaging to examine the effect of a statin - rosuvastatin (Crestor) - on the fatty plaques in arteries, was presented yesterday at the 75th European Atherosclerosis Society Congress. ORION revealed that rosuvastatin has a beneficial effect on the size and composition of fatty plaques in arteries (specifically the carotid artery in the neck). Fatty plaques that are vulnerable to sudden rupture can cause heart attacks and strokes without warning.

25 Apr 2005

Statins used before or after strokes improve outcomes

New research into the use of statins before or after a stroke has shown that a patients recovery after an ischemic stroke can be improved.

12 Apr 2005

Almonds may help combat obesity, heart disease and diabetes

Three studies presented during this week's 2005 Experimental Biology conference add to the growing body of research that eating just a handful of almonds may be a valuable tool to combat some of America's leading health threats, including obesity, heart disease and diabetes.

6 Apr 2005

Modest triglyceride elevations linked to coronary artery disease risk

Even modest increases in blood levels of triglycerides, as well as a type of high cholesterol known as type III hyperlipidemia, are strongly associated with coronary artery disease in people with a family history of the disease, according to a new study in the April 5, 2005, issue of the Journal of the American College of Cardiology.

5 Apr 2005

Dallas heart study researchers find no link between Lp(a), calcium

The latest findings from the historic Dallas Heart Study have ruled out one of the most prominent explanations of why elevated levels of a fat-carrying protein called "lipoprotein(a)" lead to increased risks for heart attacks among whites but not among African-Americans.

5 Apr 2005

Cranberry juice may help protect against heart disease

Protection against a wide variety of diseases is among the many benefits of a diet high in whole fruits and vegetables. Cranberries over the years have been identified with preventing or ameliorating urinary tract infections and playing a positive role gum disease, ulcers and even cancer.

3 Apr 2005

Simvastatin linked to protection against endothelial dysfunction in diabetic rats

Almost two years ago, the diabetes arm of the Heart Protection Study, the largest-ever study using a cholesterol-lowering medication, found that diabetics who took a daily dose of the statin drug simvastatin over five years reduced the risk of a first nonlethal heart attack by 37 percent and risk of a first nonfatal or fatal stroke by 24 percent, regardless of their cholesterol or glucose levels.

3 Apr 2005

Pcsk9 gene - new target for cholesterol-lowering drugs

Mice lacking a key protein involved in cholesterol regulation have low-density lipoprotein, or "bad" cholesterol, levels more than 50 percent lower than normal mice, and researchers suggest that inhibiting the same protein in humans could lead to new cholesterol-lowering drugs.

29 Mar 2005

Link between high cholesterol and better memory

What's bad for your ticker may be good for your bean, according to a research from a team of scientists at Boston University.

22 Mar 2005

Questions about validity of HOPE TOO vitamin E study

A study published in the March 16 issue of Journal of the American Medical Association (JAMA) suggesting that a "daily-dose" of vitamin E (400 international units) among high-risk (chronically ill) cardiovascular patient populations is associated with a greater risk of heart failure is being challenged by leading health researchers around the country who claim the study lacks the adequate research and controlled sampling audience to justify this conclusion.

16 Mar 2005

Growth hormone treatment may reduce serious metabolic conditions

Researchers in Sweden have discovered that growth hormone (GH) treatment may result in the reduction of multiple metabolic disorders associated with abdominal obesity in postmenopausal women.

14 Mar 2005

Lipitor patients who reduced 'bad' cholesterol show decrease in heart attack and stroke

Patients with coronary heart disease who took Pfizer's cholesterol-lowering medicine Lipitor (atorvastatin calcium) and lowered their cholesterol to well below recommended levels experienced significantly fewer heart attacks and strokes than those who only lowered their cholesterol to recommended levels

8 Mar 2005

Adiponectin may be helpful in finding treatments for Progeria

In a study published in the March issue of The Journal of Pediatrics, researchers found that decreased levels of HDL cholesterol, or "good" cholesterol, may contribute to premature heart disease in children with Hutchinson-Gilford Progeria Syndrome, or Progeria.

8 Mar 2005

Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women

Researchers in Sweden have discovered that growth hormone (GH) treatment may result in the reduction of multiple metabolic disorders associated with abdominal obesity in postmenopausal women.

8 Mar 2005

Researchers find way to produce cholesterol-lowering snack chips

Brandeis University biology professor K.C. Hayes and Senior Research Associate Andy Pronczuk at the school's Foster Biomedical Research Laboratory, and Senior Scientist Daniel Perlman in the Physics Department have discovered a way to produce chips and other snack foods that can actually lower your cholesterol while you eat them - without having any impact on taste

8 Feb 2005

Dietary fat quality may be more important than fat quantity in reducing risk of cardiovascular deaths in middle-aged men

The type of dietary fats consumed by middle-aged men, especially polyunsaturated fats and linoleic acids, may be more important than total fat intake in reducing the risk of cardiovascular deaths, according to a study in the January 24 issue of Archives of Internal Medicine.

24 Jan 2005