Lupus News and Research

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Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
Lymphopenia may hint a higher risk of future illness, death

Lymphopenia may hint a higher risk of future illness, death

New antibody shows promise in active lupus

New antibody shows promise in active lupus

UAB seminar on the extraordinary science of the immune system

UAB seminar on the extraordinary science of the immune system

Yale scientists flip the script on novel cancer therapy to find new insights into lupus

Yale scientists flip the script on novel cancer therapy to find new insights into lupus

UCLA scientists discover reason for higher rates of autoimmune disease in women than men

UCLA scientists discover reason for higher rates of autoimmune disease in women than men

NeutroCure project aims to cure inflammatory disease with neutrophils

NeutroCure project aims to cure inflammatory disease with neutrophils

The 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease released

The 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease released

Sphingolipids associated with heart disease in African Americans with lupus

Sphingolipids associated with heart disease in African Americans with lupus

Malaria research advances immunotherapy in lupus, HIV

Malaria research advances immunotherapy in lupus, HIV

Male patients with lupus often have more severe disease, receive little support

Male patients with lupus often have more severe disease, receive little support

Acute kidney injury on the rise in hospitalized pregnant women

Acute kidney injury on the rise in hospitalized pregnant women

New textbook on mysterious and deadly cytokine storm syndrome

New textbook on mysterious and deadly cytokine storm syndrome

Lupus flare-ups could be linked to environmental factors

Lupus flare-ups could be linked to environmental factors

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

Additional medications needed to control the symptoms of juvenile idiopathic arthritis

Additional medications needed to control the symptoms of juvenile idiopathic arthritis

Atmospheric and environmental changes linked to organ-specific lupus flares

Atmospheric and environmental changes linked to organ-specific lupus flares

New technique to detect common cause for diseases related to thrombotic microangiopathies

New technique to detect common cause for diseases related to thrombotic microangiopathies

Vitamin D and omega-3 fatty acids are not effective at reducing systemic inflammation

Vitamin D and omega-3 fatty acids are not effective at reducing systemic inflammation

Study finds molecular key to formation of mature and fully functioning T cells

Study finds molecular key to formation of mature and fully functioning T cells

Scientists pinpoint epigenetic differences in the way lupus affects black women

Scientists pinpoint epigenetic differences in the way lupus affects black women