Lupus News and Research

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Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
Male patients with lupus often have more severe disease, receive little support

Male patients with lupus often have more severe disease, receive little support

Acute kidney injury on the rise in hospitalized pregnant women

Acute kidney injury on the rise in hospitalized pregnant women

Lupus flare-ups could be linked to environmental factors

Lupus flare-ups could be linked to environmental factors

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

Additional medications needed to control the symptoms of juvenile idiopathic arthritis

Additional medications needed to control the symptoms of juvenile idiopathic arthritis

Atmospheric and environmental changes linked to organ-specific lupus flares

Atmospheric and environmental changes linked to organ-specific lupus flares

New technique to detect common cause for diseases related to thrombotic microangiopathies

New technique to detect common cause for diseases related to thrombotic microangiopathies

Vitamin D and omega-3 fatty acids are not effective at reducing systemic inflammation

Vitamin D and omega-3 fatty acids are not effective at reducing systemic inflammation

Study finds molecular key to formation of mature and fully functioning T cells

Study finds molecular key to formation of mature and fully functioning T cells

Scientists pinpoint epigenetic differences in the way lupus affects black women

Scientists pinpoint epigenetic differences in the way lupus affects black women

Study opens up array of options for developing treatments for cancer or autoimmune disorder

Study opens up array of options for developing treatments for cancer or autoimmune disorder

Celiac disease may now be curable with biodegradable nanoparticles

Celiac disease may now be curable with biodegradable nanoparticles

Neutrophil extracellular traps could cause organ damage in malaria

Neutrophil extracellular traps could cause organ damage in malaria

Study receives NCI grant to explore better treatment for brain tumors in children

Study receives NCI grant to explore better treatment for brain tumors in children

Scientists show how protein Ikaros orchestrates fine balance to control autoimmunity

Scientists show how protein Ikaros orchestrates fine balance to control autoimmunity

Study finds nearly one in three patients with lupus uses prescription opioids for pain

Study finds nearly one in three patients with lupus uses prescription opioids for pain

UAB researchers find key role for IgG autoantibodies in IgA nephropathy

UAB researchers find key role for IgG autoantibodies in IgA nephropathy

Study highlights need to educate women and medical community about risk factors of preeclampsia

Study highlights need to educate women and medical community about risk factors of preeclampsia

Improving care and educational outreach for lupus patients

Improving care and educational outreach for lupus patients

Survey says half of people with rheumatoid disease struggle to pay for treatment

Survey says half of people with rheumatoid disease struggle to pay for treatment