Lupus News and Research

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Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
Research could lead to new treatments for people with autoimmune disorders

Research could lead to new treatments for people with autoimmune disorders

An 84-year-old man saves neighbor's life, becomes oldest living kidney donor in the U.S.

An 84-year-old man saves neighbor's life, becomes oldest living kidney donor in the U.S.

Important differences found in characteristics, progression of lupus among racial/ethnic groups

Important differences found in characteristics, progression of lupus among racial/ethnic groups

New study shows how a kidney biopsy can be used to tailor treatment for lupus patients

New study shows how a kidney biopsy can be used to tailor treatment for lupus patients

‘A Vision for Lupus’ report highlights gaps and inconsistencies in care for lupus patients

‘A Vision for Lupus’ report highlights gaps and inconsistencies in care for lupus patients

HSS researchers provide better understanding of the cellular mechanisms driving rheumatoid arthritis

HSS researchers provide better understanding of the cellular mechanisms driving rheumatoid arthritis

Adverse childhood experiences associated with worse lupus symptoms

Adverse childhood experiences associated with worse lupus symptoms

Adverse childhood experiences may contribute to poor health in adults with lupus

Adverse childhood experiences may contribute to poor health in adults with lupus

Finding potential treatments for autoimmune diseases

Finding potential treatments for autoimmune diseases

Researchers examine the barriers to vaccination in immunocompromised children

Researchers examine the barriers to vaccination in immunocompromised children

FDA approves new treatment for children with lupus

FDA approves new treatment for children with lupus

CircRNAs bind to dsRNA-activated protein kinase which is linked to innate immunity

CircRNAs bind to dsRNA-activated protein kinase which is linked to innate immunity

Researchers discover why women get autoimmune diseases far more often than men

Researchers discover why women get autoimmune diseases far more often than men

Removing damaged mitochondria may relieve chronic inflammatory conditions

Removing damaged mitochondria may relieve chronic inflammatory conditions

Researchers discover unique approach to treat some chronic inflammatory diseases

Researchers discover unique approach to treat some chronic inflammatory diseases

Early molecular signs of high-risk pregnancy revealed

Early molecular signs of high-risk pregnancy revealed

Study of pregnant women with lupus identifies early indicators of pregnancy complications

Study of pregnant women with lupus identifies early indicators of pregnancy complications

Exemptions surge as parents and doctors do ‘Hail Mary’ around vaccine laws

Exemptions surge as parents and doctors do ‘Hail Mary’ around vaccine laws

Research unravels possible factor for female bias in lupus

Research unravels possible factor for female bias in lupus

Researchers developing new tests for early detection, monitoring of lupus nephritis

Researchers developing new tests for early detection, monitoring of lupus nephritis