Lupus News and Research

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Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
Knowing causative genes of osteoporosis may open door to more effective treatments

Knowing causative genes of osteoporosis may open door to more effective treatments

Researchers hope blood test that accurately diagnoses fibromyalgia could be available within five years

Researchers hope blood test that accurately diagnoses fibromyalgia could be available within five years

Fibromyalgia can be reliably detected in blood samples

Fibromyalgia can be reliably detected in blood samples

Researchers define pathway that helps us make antibodies

Researchers define pathway that helps us make antibodies

CAR-T cell therapy could be on the horizon for patients with lupus

CAR-T cell therapy could be on the horizon for patients with lupus

New approach to tackling chronic inflammatory diseases

New approach to tackling chronic inflammatory diseases

Suppressing cancer-causing protein could correct increased fibrosis in scleroderma patients

Suppressing cancer-causing protein could correct increased fibrosis in scleroderma patients

Immunologists uncover the immune system's unknown messenger

Immunologists uncover the immune system's unknown messenger

More states say doctors must offer overdose reversal drug along with opioids

More states say doctors must offer overdose reversal drug along with opioids

First therapy indicated for treating adults with rare blood clotting disorder receives FDA approval

First therapy indicated for treating adults with rare blood clotting disorder receives FDA approval

Advanced scan shows brain inflammation related to post-treatment Lyme disease syndrome

Advanced scan shows brain inflammation related to post-treatment Lyme disease syndrome

Psoriasis treatment associated with reduction in coronary artery disease

Psoriasis treatment associated with reduction in coronary artery disease

New system for early detection of lupus developed

New system for early detection of lupus developed

OU researcher and collaborators are developing new strategies for early intervention of Lupus

OU researcher and collaborators are developing new strategies for early intervention of Lupus

Immune checkpoint inhibitors induce rheumatic and musculoskeletal diseases

Immune checkpoint inhibitors induce rheumatic and musculoskeletal diseases

Lupus Research Alliance announces research awards to accelerate development of new therapies

Lupus Research Alliance announces research awards to accelerate development of new therapies

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

Researchers reveal how dietary intervention can help prevent autoimmune disease in mice

Researchers reveal how dietary intervention can help prevent autoimmune disease in mice

Lupus Research Alliance announces 2018 recipients of the Distinguished Innovator Award

Lupus Research Alliance announces 2018 recipients of the Distinguished Innovator Award

Scripps Research finds molecular cause of a group of rare autoimmune disorders

Scripps Research finds molecular cause of a group of rare autoimmune disorders