Lupus

Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
What is Lupus?

Systemic lupus erythematosus (SLE), which is more commonly referred to as lupus, is a disease that affects the immune system.

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Overview

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Latest Lupus News and Research

Atomic-level structural models of enzymes provide disease insights

Atomic-level structural models of enzymes provide disease insights

Unraveling epigenetic contributions to autoimmune skin diseases

Unraveling epigenetic contributions to autoimmune skin diseases

Exploring the power of diet: A new frontier in disease management and cancer treatment

Exploring the power of diet: A new frontier in disease management and cancer treatment

Study reveals key mechanism of PD-1 function

Study reveals key mechanism of PD-1 function

Pregnant women with autoimmune conditions at a greater risk of developing adverse pregnancy outcomes, study suggests

Pregnant women with autoimmune conditions at a greater risk of developing adverse pregnancy outcomes, study suggests

Is there a higher risk of depression among specific populations of patients with rheumatoid arthritis?

Is there a higher risk of depression among specific populations of patients with rheumatoid arthritis?

Researchers discover how "leaky" mitochondria can drive harmful inflammation

Researchers discover how "leaky" mitochondria can drive harmful inflammation

Plant-based diets trigger remission in Sjögren's syndrome and lupus cases

Plant-based diets trigger remission in Sjögren's syndrome and lupus cases

Females' immune system edges out males but at a cost of higher autoimmune risk

Females' immune system edges out males but at a cost of higher autoimmune risk

IκBζ protein holds potential for treating autoimmune conditions

IκBζ protein holds potential for treating autoimmune conditions

Exercise unleashes anti-inflammatory power against autoimmune diseases

Exercise unleashes anti-inflammatory power against autoimmune diseases

ANU discovery provides new insight into how the immune system fights malaria

ANU discovery provides new insight into how the immune system fights malaria

Mitochondrial misfire sparks inflammation

Mitochondrial misfire sparks inflammation

Monash-led study unveils potential long-term treatment for lupus

Monash-led study unveils potential long-term treatment for lupus

World-first discovery offers potential cure for lupus

World-first discovery offers potential cure for lupus

SARS-CoV-2 fragments found to mimic immune system peptides, fueling inflammation

SARS-CoV-2 fragments found to mimic immune system peptides, fueling inflammation

Xist lncRNA identified as key trigger in female-biased autoimmune diseases

Xist lncRNA identified as key trigger in female-biased autoimmune diseases

Study shows nuanced pregnancy outcomes for pregnant individuals with autoimmune disease

Study shows nuanced pregnancy outcomes for pregnant individuals with autoimmune disease

X-chromosome inactivation and its role in autoimmune susceptibility in females

X-chromosome inactivation and its role in autoimmune susceptibility in females

"Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes

"Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes

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