Lupus Erythematosus News and Research

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Researchers discover blood clotting proteins in urine as biomarkers of lupus nephritis

University of Houston researcher Chandra Mohan is reporting in Arthritis Research and Therapy that clotting proteins, both those that promote blood clots (pro-thrombotic) and those that work to dissipate them (thrombolytic), are elevated in the urine of patients who suffer from lupus nephritis (LN).

7 Aug 2019

It is okay for women with lupus to get pregnant with proper care, says new study

Systemic lupus erythematosus (SLE) is an autoimmune disease which was historically perceived to confer an unacceptably high risk to both mother and child during pregnancy. As a result, most women with the condition were counseled to avoid pregnancy or to terminate their pregnancy.

10 Jul 2019

Study shows potential culprit behind Lupus

A team of researchers at the Emory University School of Medicine show that patients with SLE or lupus, have abnormal activation of B cells, which is part of the body’s immune system

8 Jul 2019

New research offers hints to origins of systemic lupus erythematosus

New research on the autoimmune disease systemic lupus erythematosus provides hints to the origins of the puzzling disorder. The results were published in Nature Immunology.

4 Jul 2019

Researchers identify new clues on tissue damage in rheumatoid arthritis and lupus

Research supported by the Accelerating Medicines Partnership on Rheumatoid Arthritis and Systemic Lupus Erythematosus provides new insights into tissue damage for these autoimmune conditions.

19 Jun 2019

Researchers develop NO-scavenging hydrogel for treatment of rheumatoid arthritis

Nitric oxide (NO) prevents high blood pressure and artery plaque build-up in our body. However, its duplicity is shown when it causes serious inflammatory disease such as systemic lupus erythematosus, Cronh's disease, and rheumatoid arthritis.

4 Jun 2019

Research could lead to new treatments for people with autoimmune disorders

The immune system is programmed to rid the body of biological bad guys--like viruses and dangerous bacteria--but its precision isn't guaranteed. In the tens of millions of Americans suffering from autoimmune diseases, the system mistakes normal cells for malicious invaders, prompting the body to engage in self-destructive behavior.

29 May 2019

New study shows how a kidney biopsy can be used to tailor treatment for lupus patients

The kidneys of patients living with systemic lupus erythematosus are often under assault, and not all those living with the disease will respond to standard treatment.

21 May 2019

Adverse childhood experiences associated with worse lupus symptoms

Adverse childhood experiences encompass traumas such as abuse, neglect, and household challenges.

9 May 2019

Adverse childhood experiences may contribute to poor health in adults with lupus

Adults with lupus who report having had adverse childhood experiences, such as abuse, neglect and household challenges, report higher disease activity, depression and poorer overall health compared to those without such experiences, according to a study by researchers at UC San Francisco.

9 May 2019

Researchers examine the barriers to vaccination in immunocompromised children

A new study examines the barriers to vaccination of immunocompromised children. Findings from the study will be presented during the Pediatric Academic Societies 2019 Meeting, taking place on April 24 - May 1 in Baltimore.

27 Apr 2019

FDA approves new treatment for children with lupus

The U.S. Food and Drug Administration today approved Benlysta (belimumab) intravenous infusion for treatment of children with systemic lupus erythematosus – often referred to as simply "lupus" – a serious chronic disease that causes inflammation and damage to various body tissues and organs.

27 Apr 2019

CircRNAs bind to dsRNA-activated protein kinase which is linked to innate immunity

Covalently closed circular RNAs are produced by precursor mRNA back-splicing the exons of thousands of genes in eukaryotes.

26 Apr 2019

Researchers discover why women get autoimmune diseases far more often than men

It's one of the great mysteries of medicine, and one that affects the lives of millions of people: Why do women's immune systems gang up on them far more than men's do, causing nine times more women to develop autoimmune diseases such as lupus?

22 Apr 2019

Study of pregnant women with lupus identifies early indicators of pregnancy complications

A study of pregnant women with systemic lupus erythematosus has identified early changes in the RNA molecules present in the blood that could be used to determine the likelihood of them developing preeclampsia.

8 Apr 2019

Researchers developing new tests for early detection, monitoring of lupus nephritis

With $5 million in grants from the National Institutes of Health, two University of Houston biomedical researchers are moving the needle on early detection and monitoring of kidney nephritis, or inflammation, in patients who have Systemic Lupus Erythematosus, known simply as lupus.

2 Apr 2019

Researchers hope blood test that accurately diagnoses fibromyalgia could be available within five years

Ohio State University researchers have evidence that blood samples can reliably detect fibromyalgia, a disease that is often misdiagnosed due to its general symptoms that characterize a number of other conditions.

18 Mar 2019

Psoriasis treatment associated with reduction in coronary artery disease

Researchers have found that treating psoriasis, a chronic inflammatory skin disease, with biologic drugs that target immune system activity can reduce the early plaque buildup that clogs arteries, restricts blood flow, and leads to heart attacks and stroke.

5 Feb 2019

New system for early detection of lupus developed

Autoimmune diseases, such as systemic lupus erythematosus or rheumatoid arthritis, are difficult to diagnose, specially in early stages. Specifically, in the case of lupus, specific antibodies aimed at antigens located in the nucleus of cells appear, including the anti-Ro/SSA.

1 Feb 2019

OU researcher and collaborators are developing new strategies for early intervention of Lupus

A University of Oklahoma researcher, Si Wu, and collaborators from the Oklahoma Medical Research Foundation and Indiana University, are developing new strategies leading to diagnosis and early intervention of Lupus, an autoimmune disease that may affect up to 1.5 million Americans.