Lupus Erythematosus News and Research

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Daily fetal heart rate monitoring recommended for pregnant women with high anti-SSA/Ro antibodies

Physicians who care for pregnant women have long sought to identify which of their patients would most likely benefit from monitoring of their fetus's heart rate to catch early signs of their unborn child developing heart problems tied to the mother's immune system.

7 Nov 2023

Marijuana-like compound shows promise as new treatment for skin lupus

A marijuana-like compound holds out promise as a new treatment for a severe autoimmune skin disease called skin lupus, according to a study published recently by a multicenter team including researchers at the George Washington University.

2 Nov 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

AI-based method shows promise for precision medicine

Artificial intelligence, AI, which finds patterns in complex biological data could eventually contribute to the development of individually tailored healthcare.

12 Oct 2023

COVID-19 heightens risk of autoimmune disorders

SARS-CoV-2 infection may elevate risk for certain autoimmune disorders, suggests study. Regular post-COVID monitoring needed to detect and manage potential autoimmune consequences.

9 Oct 2023

Is there an association between psoriasis onset and risk of autoimmune disease?

Researchers evaluated new-onset autoimmune disease risk among individuals with new-onset psoriatic illness.

9 Oct 2023

Study reveals new insights into how the immune system prevents autoimmunity

Researchers at Stanford University School of Medicine, Yale University School of Medicine, and the Hospital for Special Surgery Research Institute have uncovered new details about how the immune system prevents the production of antibodies that can recognize and damage the body's own, healthy tissues.

29 Sep 2023

Study sheds light on potential mechanism by which psoriasis increases cardiovascular risk

In the largest study to date exploring the relationship between severe psoriasis and coronary microvascular dysfunction, researchers have found further evidence that patients with severe psoriasis are at higher cardiovascular risk.

20 Sep 2023

Study sheds new light on the role of 'TonEBP' protein in lupus and lupus nephritis

A groundbreaking discovery has been made by Professor Hyug Moo Kwon and his research team in the Department of Biological Sciences at UNIST, in collaboration with Professor Jaeseok Yang from Yonsei University.

13 Sep 2023

AI could improve accuracy and speed of lupus nephritis diagnosis

In the ever-perilous autoimmune disease world of systemic lupus erythematosus (SLE or lupus), up to 60% of adult patients and 80% of children will develop lupus nephritis (LN), and up to half of those will move on to end-stage renal disease.

12 Sep 2023

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Researchers across Europe have delved into the DNA methylation patterns in CD4+ T-cells of psoriasis and psoriatic arthritis (PsA) patients, unveiling potential new biomarkers for these conditions. Their study suggests that these unique profiles could serve as both diagnostic and prognostic tools, although further validation is needed for real-world clinical application.

10 Sep 2023

New way to administer CAR-T-cell therapy could lead to fewer side effects

When Richard O'Neil, Ph.D., joined MUSC Hollings Cancer Center two years ago, he knew that he wanted to continue finding ways to make CAR-T-cell therapy easier on patients.

8 Sep 2023

Scientists reclassify 200 rare immune system disorders using network-based approach

Scientists at CeMM, Max Perutz Labs, and St. Anna Children's Cancer Research Institute in Vienna have achieved a significant advancement in the research of rare immune system disorders.

1 Sep 2023

Study discovers method to classify febrile illness with a single blood sample

Researchers trained machine learning (ML) models to analyze RNA molecular signatures in patients’ blood.

28 Aug 2023

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Researchers described the preclinical profile of JT002, a novel and orally bioavailable small molecule inhibitor of the NLRP3 inflammasome.

24 Aug 2023

COVID-19 associated with increased risk of developing various autoimmune diseases and risk could be attenuated by vaccination

COVID-19 can increase the risk of various autoimmune diseases; however, this risk appears to be mitigated by vaccination against COVID-19.

21 Aug 2023

Powerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritis

Chandra Mohan, Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering, is reporting the first use of the powerful imaging mass cytometry (IMC) to examine the kidneys of patients with lupus (systemic lupus erythematosus), an autoimmune disease that can affect multiple organs and become fatal, and to diagnose lupus nephritis (LN) in those patients.

17 Aug 2023