Lymphatic System News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean.
After passing through the channels of the lymphatic system they drain into the lymph nodes.
The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

Developing lymphatic vessels in zebrafish

When an embryo develops, a wide variety of proteins and enzymes trigger a series of biochemical reactions. The development of the lymphatic vasculature is crucially dependent on one specific protein - the growth factor VEGF-C.

11 Jun 2020

Phase III clinical trial shows benefit of rituximab for pediatric Burkitt lymphoma

Results of the phase III Inter-B-NHL-ritux 2010 clinical trial reported today in the New England Journal of Medicine show 95 percent three-year survival for pediatric patients with advanced B-cell non-Hodgkin lymphoma treated with the addition of anti-cancer immunotherapy rituximab to standard chemotherapy.

3 Jun 2020

COVID-19 may lead to thrombosis in the lungs and subsequently multi organ failure

COVID-19, the disease caused by SARS-CoV-2, not only may lead to severe pneumonia but also to thrombosis in the lungs and, subsequently, to multi organ failure involving kidneys, liver and pancreas.

18 May 2020

Patients with aggressive form of skin cancer can benefit from new type of immunotherapy

In what is believed to be a first-of-its-kind study to evaluate the safety of a type of immunotherapy before surgery in patients with an aggressive form of skin cancer, researchers report that the treatment eliminated pathologic evidence of cancer in nearly half of the study participants undergoing surgery.

27 Apr 2020

Research suggests potential treatment target to slow lymphoma tumor growth

Researchers at the MDC observe the very early stages of blood vessel development in lymph node tumors.

7 Apr 2020

Newly discovered molecule in the lymphatic system could play a role in autoimmune diseases

A study by investigators at Hospital for Special Surgery has discovered a molecule in the lymphatic system that has the potential to play a role in autoimmune disease.

22 Mar 2020

Breast cancer cells hibernate in the lung before forming secondary tumors

Healthy lung cells support the survival of breast cancer cells, allowing them to hibernate in the lung before forming secondary tumors, according to new research from the Crick.

24 Feb 2020

New 3D model shows how breast cancer cells interact with the body’s stem cells

A Loughborough University Ph.D. student has provided new insight into how breast cancer cells interact with cells in our body by using a novel 3D model.

18 Feb 2020

Scientists track down a potential target for new sleeping sickness drugs

Using ultra-bright X-ray flashes, a team of researchers has tracked down a potential target for new drugs against sleeping sickness: The scientists have decoded the detailed spatial structure of a vital enzyme of the pathogen, the parasite Trypanosoma brucei.

30 Jan 2020

Next-generation sequencing can detect genetic alterations specific to follicular lymphoma

People with follicular lymphoma, a slow-growing lymphatic-system cancer, who have been treated and are in remission for at least two years, may no longer have what has been considered an incurable disease based on highly sensitive testing.

9 Dec 2019

$Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission$

Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission

A new, experimental immunotherapy can put patients with B-cell non-Hodgkin lymphoma (NHL) that is resistant to or has come back after multiple other therapies, including CAR T therapy, into remission.

8 Dec 2019

Multiplexed C dots track different cancer targets to improve treatment

For more than a decade, researchers have used glowing nanoparticles called Cornell dots, or C dots, to illuminate cancer cells, target tumors and even induce cell death.

6 Dec 2019

Study reveals role of corpora amylacea in expelling brain waste substances

An article published in Proceedings of the National Academy of Sciences describes a new pathway in the central nervous system to expel waste substances from the brain through the creation of corpora amylacea, aggregates formed by glucose polymers amassing waste products.

4 Dec 2019

CHLA researchers discover a mechanism of heart regeneration in zebrafish

One of the reasons coronary heart disease is so deadly is that fluid build-up and scarring can develop in the heart tissue. This prevents the heart from contracting properly, impacting its ability to supply the body with fresh blood. If scarring is extensive, heart failure can result.

12 Nov 2019

Lymphatic system found to be involved in hair regeneration

Given the amount of wear and tear it's subjected to on a daily basis, the skin has a phenomenal ability to replenish itself.

1 Nov 2019

Drugs can be safely delivered to cancerous lymph nodes using sound waves

Drugs can be safely delivered to cancerous lymph nodes via the lymphatic system and then released inside the nodes using sound waves. Tohoku University researchers tested the treatment on mice with metastatic breast cancer and published their findings in the journal Scientific Reports.

28 Oct 2019