Lymphedema News and Research

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Lymphedema is a condition that can cause significant swelling of the upper and lower extremities due to the build-up of excess lymph fluid. This can occur when the lymphatic system, which is responsible for draining excess fluid from the body and is a key component of the immune system, is damaged or altered. In breast cancer patients, this can occur after surgery, such as removal or biopsy of the lymph nodes, and/or radiation therapy. It is estimated that six percent to 40 percent of patients with breast cancer develop lymphedema, and that it often occurs within the first two years after surgery. For some cancer survivors and others at risk, a low level lymphedema can occur 10 years to 15 years following the initial primary treatment and develop into a condition that has a serious impact on overall health and quality of life.

Four new studies on the treatment of early breast cancer

Four new studies on the treatment of early breast cancer, spanning from diagnosis through surgery, were released today in advance of the 2012 Breast Cancer Symposium.

13 Sep 2012

Study to investigate how breast cancer patients might benefit from exercise

Researchers in Edmonton and Calgary want to recruit 1,500 breast cancer patients over the next decade to find out how exercise and fitness affects cancer survival and recovery.

29 Aug 2012

Liposuction effective in treating submental lymphedema in patients with head and neck cancer

Liposuction is a novel and minimally invasive procedure for treating persistent submental lymphedema in patients with previous head and neck cancer, according to an article published in the June 2012 issue of Otolaryngology-Head and Neck Surgery.

13 Jun 2012

Preoperative breast cancer pain involves an inflammatory process

Researchers from the University of California San Francisco studied a sample of women scheduled for breast cancer surgery and sought to determine the occurrence rate for preoperative breast pain, describe characteristics of the pain, evaluate the demographic and clinical variation in the women with preoperative pain, and assess the role of in pro-and anti inflammatory cytokine genes.

5 Jun 2012

Innovative model of breast cancer rehabilitation

The Prospective Surveillance Model, an innovative new model of breast cancer rehabilitation, is featured in a special supplement to the American Cancer Society's journal, Cancer released on April 6, 2012. The model addresses the numerous physical issues faced by women with breast cancer and offers hope for an improved quality of life for all women with breast cancer through rehabilitation and exercise.

18 Apr 2012

New supplement outlines prospective surveillance model for breast cancer

A new supplement in the journal Cancer outlines an innovative model to address a wide range of physical issues faced by women with breast cancer and offers hope for improved function and full participation in life activities for patients through rehabilitation and exercise.

11 Apr 2012

More than 60% of breast cancer survivors report post-treatment complications

More than 60 percent of breast cancer survivors report at least one treatment-related complication even six years after their diagnosis, according to a new study led by a researcher from the Perelman School of Medicine at the University of Pennsylvania.

10 Apr 2012

FDA clears Devon Medical Products’ extriCARE 2400 NPWT system

Devon Medical Products, a global medical device designer, manufacturer, and distributor, today announced it has received Food & Drug Administration (FDA) 510(k) clearance to market its extriCARE 2400 Negative Pressure Wound Therapy (NPWT) system.

6 Apr 2012

Transgenic mice to visualize metastasis and inflammation

One of the major routes of tumor cell dissemination to form metastasis at distant organs in the body is the lymphatic system. To study this process, still poorly understood, and to gain information on which tumors prefer this route for dissemination and how to block it, researchers of the Spanish National Cancer Research Center, led by researcher Sagrario Ortega, have created transgenic mice in which, for the first time, the growth of the lymphatic vessels can be visualized in the whole animal, by a light-emitting reaction, as tumor progresses and forms metastasis.

3 Apr 2012

New imaging probes can non-invasively detect breast cancer lymph node metastasis

Using two cell surface markers found to be highly expressed in breast cancer lymph node metastasis, researchers at Moffitt Cancer Center, working with colleagues at other institutions, have developed targeted, fluorescent molecular imaging probes that can non-invasively detect breast cancer lymph node metastasis.

13 Jan 2012

Prospective surveillance model can reduce treatment costs for breast cancer-related lymphedema

Early diagnosis and treatment of breast cancer-related lymphedema by a physical therapist can significantly reduce costs and the need for intensive rehabilitation, according to an article published in the January issue of Physical Therapy (PTJ), the scientific journal of the American Physical Therapy Association.

7 Jan 2012

Benefits of exercise for breast cancer patients with lymphedema

Lymphedema, a chronic swelling condition common in breast cancer survivors, affects three million people in the U.S. In the past, most people believed that exercise might induce or worsen lymphedema. After reviewing the literature, University of Missouri researchers say the benefits of exercise outweigh the risks for breast cancer survivors and patients with lymphedema.

2 Dec 2011

Prox1 gene plays a critical role in formation and maintenance of lymphatic system

A century after the valves that link the lymphatic and blood systems were first described, St. Jude Children's Research Hospital scientists have detailed how those valves form and identified a gene that is critical to the process.

15 Nov 2011

Conference highlights advances in evidence-based integrative therapies for cancer

Today the Society for Integrative Oncology highlighted top research findings presented at the Eighth International Conference this week in Cleveland, Ohio. More than 80 abstracts will be presented at the annual meeting, which will be keynoted by National Institutes of Health Director, Francis Collins, MD, PhD.

11 Nov 2011

NIH awards $452,218 for research on proinflammatory biomarkers and post-breast cancer lymphedema

New York University College of Nursing received a two-year, $452,218.00 grant from the national Institutes of Health to research "Proinflammatory Biomarkers and Post-Breast Cancer Lymphedema."

28 Oct 2011

New sleepwear now available for post-surgery breast cancer patients

For breast cancer patients, surgery is often the first line of treatment. Following surgery, patients must deal not only with the healing process, but also with lasting after effects such as scarring, skin sensitivity and body asymmetry. A new line of sleepwear now available to breast cancer survivors is the result of an ongoing research partnership between Ryerson University and Princess Margaret Hospital that examines how the side effects of surgery and treatment affect women's physical comfort, confidence and sexuality.

22 Oct 2011

Laurantis Pharma's Lymfactin rebuilds lymphatic vessels in pre-clinical animal models

Laurantis Pharma, a privately held biotechnology company based in Finland, today announced that Lymfactin, adenoviral VEGF-C growth factor therapy, was successful in rebuilding lymphatic vessels in pre-clinical animal models.

26 Sep 2011

New studies on breast cancer screening, treatment and survival

New studies on breast cancer screening, treatment, and survival were released today in advance of the 2011 Breast Cancer Symposium. The symposium is being held September 8-10, 2011, at the San Francisco Marriott Marquis in San Francisco.

8 Sep 2011

Researchers discover new genetic defect that predisposes people to leukemia, myelodysplasia

A new genetic defect that predisposes people to acute myeloid leukemia and myelodysplasia has been discovered. The mutations were found in the GATA2 gene. Among its several regulatory roles, the gene acts as a master control during the transition of primitive blood-forming cells into white blood cells.

5 Sep 2011

Cancer Information Service celebrates helping one million Canadians

Fear, anxiety, helplessness, anger - these are some of the often overwhelming feelings that people can encounter when dealing with cancer. When faced with a cancer diagnosis, knowledge is power. The Canadian Cancer Society empowers Canadians with timely cancer information so that people can make informed decisions about their health.

5 Aug 2011