Lymphocytic Choriomeningitis News and Research

RSS
Lymphocytic choriomeningitis, or LCM, is a rodent-borne viral infectious disease that presents as aseptic meningitis (inflammation of the membrane, or meninges, that surrounds the brain and spinal cord), encephalitis (inflammation of the brain), or meningoencephalitis (inflammation of both the brain and meninges). Its causative agent is the lymphocytic choriomeningitis virus (LCMV), a member of the family Arenaviridae that was initially isolated in 1933. Although LCMV is most commonly recognized as causing neurological disease, as its name implies, infection without symptoms or mild febrile illnesses are common clinical manifestations. Additionally, pregnancy-related infection has been associated with congenital hydrocephalus, chorioretinitis, and mental retardation.
CRISPR RNA-cutting enzyme programmed to destroy viruses in human cells

CRISPR RNA-cutting enzyme programmed to destroy viruses in human cells

New insight may allow researchers to design drugs that improve immune responses to vaccines

New insight may allow researchers to design drugs that improve immune responses to vaccines

Swiss scientists create artificial viruses to combat cancer cells

Swiss scientists create artificial viruses to combat cancer cells

Experimental treatment tempers HLH, MS symptoms in mouse models, study shows

Experimental treatment tempers HLH, MS symptoms in mouse models, study shows

Research findings could lead to development of novel therapeutic approaches against viral infections

Research findings could lead to development of novel therapeutic approaches against viral infections

Suppressed vaginal immune response makes women more susceptible to RNA viruses

Suppressed vaginal immune response makes women more susceptible to RNA viruses

TSRI researchers uncover mechanism behind T cell exhaustion

TSRI researchers uncover mechanism behind T cell exhaustion

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

SBP scientists discover new regulator of immune responses

SBP scientists discover new regulator of immune responses

TSRI study reveals important traits in LCMV, Lassa virus

TSRI study reveals important traits in LCMV, Lassa virus

Penn Medicine researchers explore primary player involved in T cell exhaustion

Penn Medicine researchers explore primary player involved in T cell exhaustion

Interferon Type I immune proteins key drivers of human hemorrhagic fevers

Interferon Type I immune proteins key drivers of human hemorrhagic fevers

Findings highlight importance of IL-21 in the development of antiviral vaccines

Findings highlight importance of IL-21 in the development of antiviral vaccines

Drug molecules designed for influenza may be adapted to treat other viruses

Drug molecules designed for influenza may be adapted to treat other viruses

Single protein determines persistence of viral infection

Single protein determines persistence of viral infection

Researchers identify primary player of the biochemical bugle call

Researchers identify primary player of the biochemical bugle call

MDA5 molecule plays a critical role in fighting viral infections

MDA5 molecule plays a critical role in fighting viral infections

ONPRC researchers discover new method to create safe and effective vaccines

ONPRC researchers discover new method to create safe and effective vaccines

Fresh cells can pep talk immune cells exhausted by HIV or hepatitis C

Fresh cells can pep talk immune cells exhausted by HIV or hepatitis C

Scientists determine atomic structure of Lassa fever viral protein

Scientists determine atomic structure of Lassa fever viral protein