Lymphocytic Choriomeningitis News and Research

RSS
Lymphocytic choriomeningitis, or LCM, is a rodent-borne viral infectious disease that presents as aseptic meningitis (inflammation of the membrane, or meninges, that surrounds the brain and spinal cord), encephalitis (inflammation of the brain), or meningoencephalitis (inflammation of both the brain and meninges). Its causative agent is the lymphocytic choriomeningitis virus (LCMV), a member of the family Arenaviridae that was initially isolated in 1933. Although LCMV is most commonly recognized as causing neurological disease, as its name implies, infection without symptoms or mild febrile illnesses are common clinical manifestations. Additionally, pregnancy-related infection has been associated with congenital hydrocephalus, chorioretinitis, and mental retardation.
ONPRC researchers discover new method to create safe and effective vaccines

ONPRC researchers discover new method to create safe and effective vaccines

Fresh cells can pep talk immune cells exhausted by HIV or hepatitis C

Fresh cells can pep talk immune cells exhausted by HIV or hepatitis C

Scientists determine atomic structure of Lassa fever viral protein

Scientists determine atomic structure of Lassa fever viral protein

SIGA completes fourth human clinical trial of ST-246 smallpox antiviral drug candidate

SIGA completes fourth human clinical trial of ST-246 smallpox antiviral drug candidate

Findings could guide in developing more effective vaccines for HIV/AIDS and cancer

Findings could guide in developing more effective vaccines for HIV/AIDS and cancer

Scientists find key to strengthening immune response to chronic infection

Scientists find key to strengthening immune response to chronic infection

Sticky protein protects cells from mechanical stress

Sticky protein protects cells from mechanical stress

Transplant drug Rapamycin stimulates immune memory

Transplant drug Rapamycin stimulates immune memory

Discovery of new arenavirus associated with hemorrhagic fever – first identified in nearly four decades

Discovery of new arenavirus associated with hemorrhagic fever – first identified in nearly four decades

Chronic infection clearly linked to key immunity protein

Chronic infection clearly linked to key immunity protein

New insights into immune exhaustion

New insights into immune exhaustion

Blocking immune receptor molecule improves response to HIV-like virus, prolongs survival in monkeys

Blocking immune receptor molecule improves response to HIV-like virus, prolongs survival in monkeys

Scientists find key to keeping killer T cells in prime shape for fighting infection, cancer

Scientists find key to keeping killer T cells in prime shape for fighting infection, cancer

Scientists discover new cause of fatal brain injury from acute viral meningitis

Scientists discover new cause of fatal brain injury from acute viral meningitis

Chronic infection persists by targeting stromal cell network in lymphoid organs

Chronic infection persists by targeting stromal cell network in lymphoid organs

Organ-recipients' deaths prompt call for suppliers of pet rodents to screen for lymphocytic choriomeningitis virus

Organ-recipients' deaths prompt call for suppliers of pet rodents to screen for lymphocytic choriomeningitis virus

Six deaths in transplant patients now linked to rodent virus

Six deaths in transplant patients now linked to rodent virus

Virus from rodents kills three transplant recipients

Virus from rodents kills three transplant recipients