Lymphocytic Choriomeningitis News and Research

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Lymphocytic choriomeningitis, or LCM, is a rodent-borne viral infectious disease that presents as aseptic meningitis (inflammation of the membrane, or meninges, that surrounds the brain and spinal cord), encephalitis (inflammation of the brain), or meningoencephalitis (inflammation of both the brain and meninges). Its causative agent is the lymphocytic choriomeningitis virus (LCMV), a member of the family Arenaviridae that was initially isolated in 1933. Although LCMV is most commonly recognized as causing neurological disease, as its name implies, infection without symptoms or mild febrile illnesses are common clinical manifestations. Additionally, pregnancy-related infection has been associated with congenital hydrocephalus, chorioretinitis, and mental retardation.
Transplant drug Rapamycin stimulates immune memory

Transplant drug Rapamycin stimulates immune memory

Discovery of new arenavirus associated with hemorrhagic fever – first identified in nearly four decades

Discovery of new arenavirus associated with hemorrhagic fever – first identified in nearly four decades

Chronic infection clearly linked to key immunity protein

Chronic infection clearly linked to key immunity protein

New insights into immune exhaustion

New insights into immune exhaustion

Blocking immune receptor molecule improves response to HIV-like virus, prolongs survival in monkeys

Blocking immune receptor molecule improves response to HIV-like virus, prolongs survival in monkeys

Scientists find key to keeping killer T cells in prime shape for fighting infection, cancer

Scientists find key to keeping killer T cells in prime shape for fighting infection, cancer

Scientists discover new cause of fatal brain injury from acute viral meningitis

Scientists discover new cause of fatal brain injury from acute viral meningitis

Chronic infection persists by targeting stromal cell network in lymphoid organs

Chronic infection persists by targeting stromal cell network in lymphoid organs

Organ-recipients' deaths prompt call for suppliers of pet rodents to screen for lymphocytic choriomeningitis virus

Organ-recipients' deaths prompt call for suppliers of pet rodents to screen for lymphocytic choriomeningitis virus

Six deaths in transplant patients now linked to rodent virus

Six deaths in transplant patients now linked to rodent virus

Virus from rodents kills three transplant recipients

Virus from rodents kills three transplant recipients