Lymphoma News and Research

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Lymphoma is cancer that begins in cells of the immune system. There are two basic categories of lymphomas. One kind is Hodgkin lymphoma, which is marked by the presence of a type of cell called the Reed-Sternberg cell. The other category is non-Hodgkin lymphomas, which includes a large, diverse group of cancers of immune system cells. Non-Hodgkin lymphomas can be further divided into cancers that have an indolent (slow-growing) course and those that have an aggressive (fast-growing) course. These subtypes behave and respond to treatment differently. Both Hodgkin and non-Hodgkin lymphomas can occur in children and adults, and prognosis and treatment depend on the stage and the type of cancer.

Abbott receives approval for HUMIRA (Adalimumab) for polyarticular juvenile idiopathic arthritis

Abbott has announced that it has received U.S. Food and Drug Administration (FDA) approval to market HUMIRA (adalimumab) as a treatment to reduce signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (JIA) in patients four years of age and older.

26 Feb 2008

Study offers insight into possible cause of lymphoma

The immune system's powerful cellular mutation and repair processes appear to offer important clues as to how lymphatic cancer develops, Yale School of Medicine researchers report this week in Nature.

18 Feb 2008

New cancer center at NewYork-Presbyterian/Weill Cornell

NewYork-Presbyterian Hospital/Weill Cornell Medical Center has created an expanded cancer program dedicated to advancing research, prevention and treatment of the disease. The new Cancer Center is led by renowned cancer physician-scientist Dr. Andrew Dannenberg.

5 Feb 2008

Enbrel shown to significantly reduced levels of C-reactive protein

Amgen and Wyeth Pharmaceuticals, a division of Wyeth have announced findings from a retrospective analysis, which demonstrated that ENBREL reduced C-reactive protein (CRP), a marker of inflammation, in patients with moderate to severe plaque psoriasis following 12 weeks of treatment. Median reduction in CRP levels was 10 times greater in the ENBREL treated group compared to the placebo treated group.

5 Feb 2008

Kidney cancer drug attacks a major type of acute myeloid leukemia

A drug used to treat kidney cancer also targets a genetic mutation active in about one third of patients with acute myeloid leukemia (AML), the most common and lethal form of adult leukemia, researchers at The University of Texas M. D. Anderson Cancer Center report in the Jan. 29 edition of the Journal of the National Cancer Institute.

30 Jan 2008

Stanford study finds transplant patient thrives 2 years after stopping immunosuppressive drugs

Luck smiled on Larry Kowalski when his brother agreed to donate a kidney Kowalski needed to live.

24 Jan 2008

Genmab reaches milestones in Ofatumumab collaboration

The second milestone payment of the collaboration of DKK 87.2 million was triggered by treatment of the first patient in the Phase II study of ofatumumab in Diffuse Large B-Cell Lymphoma (DLBCL), which occurred in 2007.

22 Jan 2008

Culprit cell for childhood leukaemia discovered

A study by British researchers of twin girls has identified a rogue cell that is the fundamental cause of childhood leukaemia.

20 Jan 2008

Extra-hepatic manifestation of hepatitis C virus infection

In 1994, the team of Tchernev and Petrova from Alexandrovska Hospital in Sofia examined a female patient with liver cirrhosis caused by chronic Hepatitis C virus (HCV).

17 Jan 2008

Genmab announces HuMax-CD32b pre-clinical program

Genmab A/S has announced a new pre-clinical antibody program called HuMax-CD32b. This fully human IgG1,k antibody targets the CD32b receptor found on immune cells and hematological tumors.

7 Jan 2008

Study to look at effect of high dose vitamin C on non-Hodgkin lymphoma patients

Scientists at Thomas Jefferson University Hospital and Jefferson's Kimmel Cancer Center have received approval for a first-of-its kind study on the effect high dose vitamin C has on non-Hodgkin lymphoma patients.

3 Jan 2008

Rituximab used to treat skin disorders

A new review article from the journal Dermatologic Therapy reveals that rituximab, a drug used to treat lymphoma, is now becoming used by dermatologists to treat various dangerous skin diseases.

17 Dec 2007

Researchers zero in on the tiniest members in the war on cancer

Researchers from the University of Pennsylvania and Johns Hopkins University have uncovered another reason why one of the most commonly activated proteins in cancer is so dangerous.

14 Dec 2007

PET/CT imaging proves golden for detecting cancer in children

PET/CT imaging exhibits significantly higher sensitivity, specificity and accuracy than conventional imaging when it comes to detecting malignant tumors in children, according to research published in the December issue of the Journal of Nuclear Medicine.

13 Dec 2007

Novel way to diagnose mantle cell lymphomas

Mantle cell lymphoma is an aggressive form of blood cancer that most commonly afflicts older men.

13 Dec 2007

Researchers advance stem cell gene therapy

Ireland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with less severe side effects.

13 Dec 2007

Need for education for primary care physicians on rarely seen cancers

Many primary care physicians may lack the necessary knowledge when it comes to recognizing the signs, symptoms and making proper diagnoses in cases of blood cancers such as leukemia and lymphoma, a recent survey indicates.

10 Dec 2007

Silencing small but mighty cancer inhibitors

Researchers from Johns Hopkins and the University of Pennsylvania have uncovered another reason why one of the most commonly activated proteins in cancer is in fact so dangerous.

10 Dec 2007

Patients without advance care plans more likely to die

Researchers at the University of Nebraska Medical Center (UNMC) in Omaha and the Fred Hutchinson Cancer Research Center in Seattle found only half of patients undergoing stem cell transplantation had advance care plans - documents such as living wills, power of attorney for health care, or life-support instructions - and those without plans were three times more likely to die during or after surgery.

10 Dec 2007

Mild chemo before stem cell transplant causes long-term remission of follicular lymphoma

Treating relapsed follicular lymphoma patients with a milder chemotherapy regimen before they receive a blood stem cell transplant from a donor resulted in long-term complete remission for 45 of 47 patients in a clinical trial, researchers at The University of Texas M. D. Anderson Cancer Center report at the 49th annual meeting of the American Society of Hematology.

10 Dec 2007