Lyophilization News and Research

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Freeze-drying, also referred to as lyophilization, is a process that involves freezing a substance at very low temperatures and then extracting liquid via sublimation, converting water from a solid to gaseous state.

Synthetic biological logic gate could one day be used to modify cellular function

Genes in living cells are activated - or not - by proteins called transcription factors. The mechanisms by which these proteins activate certain genes and deactivate others play a fundamental role in many biological processes.

26 Mar 2019

Freeze dried polio vaccine could help save lives in remote locations

Polio vaccine can successfully prevent the deadly paralyzing illness caused in children. The vaccine presently available is in liquid form and is also thermolabile.

28 Nov 2018

KTU researchers engineer experimental bone to help treat osteoarthritis patients

Researchers from the Faculty of Chemical Technology, Kaunas University of Technology (KTU), Lithuania are developing an artificial bone, which can be used for treating of the most common joint disease - osteoarthritis.

26 Sep 2018

New simple flame burning method to prepare SWNT sponges on a large scale

In a paper published in NANO, a group of researchers have developed a simple flame burning method to prepare single-walled carbon nanotube (SWNT) sponges on a large scale. The SWNT sponge has multifunctional properties and can be used in the fields of cleaning-up, sensing and energy storage.

24 Aug 2018

New approach to cultivate hypoallergenic tomato and strawberry varieties

The incidence of food allergies has increased in recent decades: It affects three to four percent of the adult population and five percent of children.

16 Jul 2018

CellGenix completes first phase of facility expansion to meet rising demands for GMP cell culture reagents

CellGenix, a global manufacturing leader of GMP-grade raw materials for cell therapy, gene therapy and tissue-engineered products, successfully completed the first phase of its headquarters’ expansion as more customers approach late-stage clinical development and commercialization.

22 Jun 2018

Lithuanian researchers use freeze-drying technique to create sponge-like wound dressings

Group of researchers at Kaunas University of Technology, Lithuania are developing new generation sponge-like wound dressings with hyaluronic acid. Antimicrobial, antioxidant, anti-inflammatory wound dressings stimulate tissue regeneration and can be especially efficient in treating deep wounds that are difficult to heal.

12 Apr 2018

SP Scientific’s Freezemobile freeze dryer provides convenient, flexible solution for Life Science labs

The Freezemobile freeze dryer from SP Scientific is designed to provide a convenient and flexible solution for high-quality preparation of peptides, proteins, plant materials and organic tissue.

12 Feb 2018

Study confirms capabilities of SP Scientific’s new LyoCapsule Freeze Dryer

SP Scientific announces publication of an independent study evaluating their LyoCapsule Freeze Dryer for pharmaceutical product formulation and process development.

28 Nov 2017

Scientists develop antibacterial ‘sugar-glass’ coating that uses viruses to destroy bacteria

With antibiotic resistance on the rise, bacterial contamination of food is becoming more problematic. Now in a study appearing in ACS Biomaterials Science & Engineering, scientists report that they have developed an antibacterial "sugar-glass" coating in which viruses that destroy bacteria are embedded and are kept stable for up to three months.

8 Nov 2017

Research expands range in dry preservation of mammalian sperm cells

In a paper forthcoming in the November issue of the journal Theriogenology, a team of researchers from the University of North Carolina at Charlotte and the Smithsonian Conservation Biology Institute, announced the first successful drying and rehydration of domestic cat spermatozoa using a rapid microwave dehydration method.

12 Oct 2017

Mouse sperm subjected to cosmic environment still produces healthy offspring, report researchers

Freeze-dried mouse sperm that spent nine months in the harsh environment of space have successfully fertilized eggs and produced healthy offspring in mice.

23 May 2017

Tiny silica 'cages' could help store and transport vaccines without refrigeration

Vaccines and antibodies could be transported and stored without refrigeration by capturing them in tiny silica 'cages', a discovery which could make getting vital medicines to remote or dangerous places much easier, cheaper and safer.

24 Apr 2017

Linkam introduces new FDVS platform to replicate large scale freeze drying processes

Market leaders in temperature controlled microscopy and established manufacturers of advanced freeze drying microscopes, Linkam Scientific Instruments, announce the launch of the FDVS platform, a lyophilisation system to replicate large scale freeze drying processes.

16 Nov 2016

SP Scientific introduces powerful free software resource for freeze drying users

SP Scientific announces the introduction of the LyoModelling Calculator (LMC) - a powerful new software utility that enables those developing freeze drying cycles to calculate the time required for primary drying and the maximum product temperature based on user data input.

11 Jul 2016

Ajinomoto Althea expands biological drug product manufacturing operations

Ajinomoto Althea, Inc., a leading provider of biopharmaceutical contract development and manufacturing services, recently announced it is expanding its existing biological drug product manufacturing operations to include highly active materials such as Antibody Drug Conjugates (ADCs).

10 Dec 2015

AMRI purchases Gadea Pharmaceutical Group for $174 million

AMRI today announced that it has acquired all the outstanding shares of Gadea Pharmaceutical Group, a privately-held company located in Valladolid, Spain, specializing in technically complex active pharmaceutical ingredients (APIs) and finished drug product.

16 Jul 2015

Researchers develop mesoporous particles for use as drug delivery system

A research group led by MANA Scientist Kohsaku Kawakami, postdoctoral researcher Shaoling Zhang and MANA Principal Investigator Katsuhiko Ariga, at the International Center for Materials Nanoarchitectonics (MANA), NIMS (Sukekatsu Ushioda, President), succeeded in developing porous particles (mesoporous particles) consisting solely of phospholipids, a biological component, that are suitable for use as a drug delivery system.

10 Jun 2015

Theravectys gets authorization to produce lentiviral vectors for clinical use and CAR-T cell-based immunotherapy

THERAVECTYS, a clinical development biotechnology company that focuses on the development of therapeutic vaccines and immunotherapies, proudly announces that its manufacturing plant has obtained the status of a pharmaceutical manufacturing establishment, granted by the French National Agency for Medicines and Health Products Safety.

26 Mar 2015

Particle Sciences to expand sterile manufacturing for complex products and particulates

Particle Sciences, Inc (PSI), the leading CDMO for micro and nano-particulates is expanding its sterile and aseptic manufacturing capacity generally and specifically for nano-milled drug products.

9 Mar 2015