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Bioelectronic 'nose' can easily sniff foul smells in rotting food

Strong odors are an indicator that food has gone bad, but there could soon be a new way to sniff foul smells earlier on.

6 Dec 2017

Study: New histone modifications link cellular metabolism to chromatin architecture

Scientists of Helmholtz Zentrum München and Ludwig-Maximilians-Universität Munich (LMU) have discovered that two new classes of histone modifications couple cellular metabolism to gene activity. The study was published in 'Nature Structural and Molecular Biology'.

26 Oct 2017

Researchers propose LSD1 protein as central player in Alzheimer's and FTD

Removal of a regulatory gene called LSD1 in adult mice induces changes in gene activity that that look unexpectedly like Alzheimer's disease, scientists have discovered.

9 Oct 2017

Discovery of key brain cells that control appetite could revolutionize dieting

Dieting could be revolutionized, thanks to the ground-breaking discovery by the University of Warwick of the key brain cells which control our appetite.

27 Sep 2017

New molecular compound improves balance and coordination in mouse model of Parkinson's disease

Researchers at UCLA have developed a molecular compound that improves balance and coordination in mice with early stage Parkinson's disease.

13 Jun 2017

Study points to new pharmacologic approach to target chemo-resistant lung cancer

Patients with non-small cell lung cancer (NSCLC) often respond to standard chemotherapy, only to develop drug resistance later, and with fatal consequences.

23 May 2017

Research findings reveal new approach to prevent age-related obesity

The function and distribution of adipose tissue in the body change during the course of life. Beige fat cells, a special type of adipocytes, have the capability to use energy reserves - fatty deposits - by generating heat in a process known as thermogenesis.

4 May 2017

Study provides new understanding of molecular mechanisms of HPV-induced tumors

The incidence of human papillomavirus (HPV)-associated (HPV+) head and neck squamous cell carcinoma (HNSCC) of the oropharynx has dramatically increased over the last decade and is now more frequently diagnosed than uterine cervical cancer in the United States.

31 Mar 2017

Study reveals intriguing crosstalk between metabolism and epigenetics in cancer development

A study published in Briefings in Functional Genomics investigated how epigenetics can modulate human's genetic program -- it can emphasize or silence genes.

24 Mar 2017

EPFL scientists develop synthetic methods to crack code of Huntington's disease

Huntington's disease is a neurodegenerative disorder that causes patients to lose their ability to move, speak, and even think. It is caused by a gene mutation that produces an abnormal form of the protein huntingtin, which aggregates and builds up inside neurons of the cortex and striatum.

23 Mar 2017

New class of membrane-busting compounds can combat MRSA skin infections in mice

Public health officials are increasingly concerned over methicillin-resistant Staphylococcus aureus (MRSA). The bacteria have developed resistance to a number of treatments, even antibiotics of last resort in some cases.

15 Mar 2017

SETD8 enzyme protects against cellular senescence, research reveals

An enzyme that blocks cellular senescence and its mechanisms has been discovered by a research team from Kumamoto University, Japan. They found that a reduction of the enzyme SETD8, which regulates cell proliferation and gene function, results in the promotion of cell aging features.

8 Mar 2017

Spectroscopy and computer help RUB scientists gain new insights into workings of protein switches

Using a combination of infrared spectroscopy and computer simulation, researchers at Ruhr-Universität Bochum have gained new insights into the workings of protein switches.

16 Jan 2017

Editing preferences of enzymes may play role in infertility and cancer

To "turn off" particular regions of genes or protect them from damage, DNA strands can wrap around small proteins, called histones, keeping out all but the most specialized molecular machinery.

28 Nov 2016

Epigenetic enzyme plays key role in maintaining metabolic properties of brown fat, research shows

In mammals, three types of adipose tissues exist. White adipocytes are mainly located in the abdominal and subcutaneous areas of the body and highly adapted to store excess energy.

31 Oct 2016

Penicillin allergy testing: an interview with Dr. Eric Macy

Penicillin was one of the first antibiotics developed and has saved millions of lives. First used in the early 1940s, penicillin is still one of the most widely used and least toxic family of antibiotics.

17 Aug 2016

Scientists create stable boron carrier for targeted radiation-based tumour therapies

Targeted radiation-based therapies for treating cancerous tumours such as 'boron neutron capture therapy' (BNCT), rely on the efficient and effective delivery of the capture agent (in this case, boron) to the tumour.

11 Aug 2016

New technology could help deliver treatments for brain injuries

A new study led by scientists at the Sanford Burnham Prebys Medical Discovery Institute describes a technology that could lead to new therapeutics for traumatic brain injuries. The discovery, published today in Nature Communications, provides a means of homing drugs or nanoparticles to injured areas of the brain.

29 Jun 2016

Researchers investigate why N14Y, N14K mutations have distinct effects in KID syndrome patients

A team of New York-based researchers has compared the effects of two disease-causing mutations, potentially explaining why patients with the rare genetic disorder keratitis-ichthyosis-deafness (KID) syndrome can experience different sets of symptoms.

28 Jun 2016

Single enzyme doing the work of a trio could offer precise way to treat diseases

Researchers identified a single enzyme doing the work of a trio thought necessary to control a common cellular signaling process being pursued as a therapeutic target.

24 May 2016