MALDI TOF News and Research

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Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry is a soft ionization method used in the detection of various chemical compounds with a broad mass range. MALDI-TOF can be applied in biology to the study of nucleic acids and proteins.

Early detection of breast cancer could soon be possible with blood test

What could someday be the first blood test for the early detection of breast cancer was shown in preliminary studies to successfully identify the presence of breast cancer cells from serum biomarkers, say the Houston Methodist Research Institute scientists who are developing the technology.

15 Nov 2013

Sequenom announces Certified Service Provider program for technical certification

Sequenom, Inc., a life sciences company providing innovative diagnostic testing and genetic analysis solutions, today announced a Certified Service Provider (CSP) program for the technical certification of selected laboratories offering research services using the Sequenom research-use-only MassARRAY System.

18 Sep 2013

Bruker Launches Second Phase Of SISCAPA-MALDI Collaboration

After focusing on confirming the utility and quantitative precision of the SISCAPA-MALDI workflow in the collaboration's first phase, Bruker said it plans to establish fully automated SISCAPA-MALDI capabilities in its demonstration facilities.

16 Sep 2013

FDA approves first mass spectrometer system in U.S. for identification of bacteria, yeasts

The U.S. Food and Drug Administration today allowed marketing in the U.S. of the first mass spectrometer system for automated identification of bacteria and yeasts that are known to cause serious illness in humans.

22 Aug 2013

Bruker launches BioPharmaCompass 1.1 software

At the 2012 CASSS 9th Symposium on the Practical Applications of Mass Spectrometry in the Biotechnology Industry, Bruker today launches the first software solution to encompass the complete biopharmaceutical characterization challenge, including glycoforms, impurities and modifications.

From Bruker BioSpin - NMR, EPR and Imaging 12 Sep 2012

Accelr8 expands development plan for BACcel rapid diagnostic test

Accelr8 Technology Corporation announced that it successfully completed two technical feasibility studies for test methods that expand its BACcel rapid diagnostic test library and automation capabilities.

23 Nov 2011

Bruker to showcase record performance achievements of maXis 4G system at ASMS 2011

Bruker, the pioneer of ultrahigh-resolution quadrupole time-of-flight mass spectrometry, today announced a major extension of the successful maXis UHR Qq-TOF technology range, which Bruker will showcase at the ASMS 2011 conference in Denver, Colorado, starting this Sunday, June 5.

3 Jun 2011

NewGene develops breakthrough test for hereditary breast cancer

A new breakthrough test for hereditary breast cancer developed by UK-based NewGene could see thousands of women being diagnosed with the genetic condition in around half the usual time and at around half the cost of conventional test methods.

16 May 2011

New technique can reveal fat distribution in healthy human brain

Mapping the fat distribution of the healthy human brain is a key step in understanding neurological diseases, in general, and the neurodegeneration that accompanies Alzheimer's disease in particular. Antonio Veloso and colleagues, from the University of the Basque Country in Leioa, Spain, find a new technique to reveal the fat distribution of three different areas of the healthy human brain.

5 May 2011

Bruker receives Health Canada approval for IVD MALDI Biotyper

At the 2011 Annual Meeting of the Canadian Association for Clinical Microbiology and Infectious Diseases, the companies i2A Canada and Bruker Ltd. announced together that they have met the relevant Health Products and Food Branch of Health Canada regulations for the Bruker IVD MALDI Biotyper, and that this product is now available for sale as a Class 1 Medical Device to all clinical microbiology sites in Canada.

8 Apr 2011

ICR, AB SCIEX collaborate to standardize mass spectrometry-based tissue imaging

A key research area for The Institute of Cancer Research is investigating the spread of cancer in the human body in an effort to identify new and effective treatment strategies. To help advance this research, the ICR is collaborating with scientists at AB SCIEX, a global leader in life science analytical technologies, to standardize advanced methods of mass spectrometry-based tissue imaging.

17 Feb 2011

Scientists improve methods for flavanol antioxidant determination in cocoa, chocolate

Two scientific publications report on improved methods for determining the amounts of flavanol antioxidants in cocoa and chocolate. The research, sponsored by The Hershey Center for Health and Nutrition, was a collaboration between scientists at The Hershey Company and other scientific laboratories.

15 Feb 2011

Protein cross-linking enzymes in foods can affect physiological characteristics

Protein modification via enzymatic cross-linking is an attractive way for altering food structure so as to create products with increased quality and nutritional value. These modifications are expected to affect not only the structure and physico-chemical properties of proteins but also their physiological characteristics, such as digestibility in the GI-tract and allergenicity.

10 Feb 2011

APHP selects Bruker´s Biotyper as exclusive MALDI-TOF mass spectrometry for microbial identification

At the 30th Reunion Interdisciplinaire de Chimothérapie Anti-Infectieuse (RICAI), Bruker announces that the Assistance Publique Hôpitaux de Paris (APHP) has selected Bruker´s IVD MALDI Biotyper as their exclusive MALDI-TOF mass spectrometry-based microbial identification tool.

2 Dec 2010

Researchers develop tools to visualize how different cell populations of cells communicate

Using imaging mass spectrometry, researchers at the University of California, San Diego have developed tools that will enable scientists to visualize how different cell populations of cells communicate. Their study shows how bacteria talk to one another - an understanding that may lead to new therapeutic discoveries for diseases ranging from cancer to diabetes and allergies.

9 Nov 2009

Three German laboratories utilize Bruker’s molecular identification solution

At the 61st Annual Meeting of the German Society for Hygiene and Microbiology on September 20-23, 2009 in Goettingen, Bruker Daltonics announces that three major German private clinical microbiology laboratories have extended their accreditation according to DIN EN ISO 15189 to include the use of Bruker’s MALDI Biotyper molecular identification solution.

21 Sep 2009