MMR News and Research

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Immunization shots effective at preventing measles

High fever. Cough. Runny nose. Red, watery eyes. It may not be the flu. It could be measles.

30 Aug 2018

Measles cases on the rise in Europe

According to the World Health Organization (WHO), there is a sharp rise in the number of measles cases across Europe in the first six months of this year. Measles has affected over 41,000 individuals and killed 37, says the WHO.

20 Aug 2018

Genomic markers can predict lynch syndrome across tumor types

Microsatellite instability and DNA mismatch repair deficiencies can predict Lynch syndrome across tumor types, according to researchers from Memorial Sloan Kettering Cancer Center, who presented this retrospective data analysis in a press conference at the annual meeting of the American Society of Clinical Oncology.

4 Jun 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

Researchers use human and worm data to explore mutational causes of cancer

Researchers at the European Bioinformatics Institute (EMBL-EBI), the University of Dundee and the Wellcome Sanger Institute have used human and worm data to explore the mutational causes of cancer.

2 May 2018

Computer-based intervention to increase parents’ knowledge about HPV vaccination

It's been almost 30 years since Salt-N-Pepa implored Americans to set their puritanical misgivings aside and talk about sex, and yet we still struggle with the subject; that fact is abundantly clear when you consider national HPV vaccination rates.

16 Apr 2018

Precancerous colon polyps in Lynch syndrome patients display immune activation

Colon polyps from patients with Lynch syndrome, a hereditary condition that raises colorectal cancer risk, display immune system activation well before cancer development, according to research from The University of Texas MD Anderson Cancer Center.

16 Apr 2018

Legacy of social and political factors may be responsible for vaccine hesitancy

A legacy of social and political factors rather than bad parenting may be influencing people's decisions not to vaccinate their children, according to a study from the University of Waterloo.

9 Apr 2018

Misconceptions about MMR vaccine found to influence usage of Zika vaccine

People's willingness to use a Zika vaccine when it's available will be influenced by how they weigh the risks associated with the disease and the vaccine, but also by their misconceptions about other vaccines, a new study has found.

15 Mar 2018

Australian brings measles to New York sparking fears for unvaccinated

According to the city officials in New York, the small population of unvaccinated individuals need to be extra careful over the next couple of weeks because an Australian individual with suspected measles has arrived in the city. This announcement was made last Friday by the New York State Department of Health.

26 Feb 2018

Reminders can improve immunization rates

Rates of immunization against infectious diseases in children and adults are improving, but under-vaccination remains a problem that results in vaccine-preventable deaths and illnesses. In Europe, 11,316 cases of measles were reported during 2012, and an estimated four to 50 million symptomatic cases of flu occur each year.

19 Jan 2018

Measles outbreak alarms public health officials

According to the Public Health England (PHE) there are “large outbreaks” of measles in Europe that is cause for concern.

16 Jan 2018

Study finds a cellular mechanism that protects plant genes from impacts of mutation

According to a new study conducted at the University of Oxford, a cellular mechanism termed DNA mismatch repair (MMR), preferentially protects plant genes from the damaging impacts of mutation.

8 Jan 2018

Cellular mechanism protects genes from damaging effects of mutation

Researchers at the University of Oxford have discovered that a cellular mechanism preferentially protects plant genes from the damaging effects of mutation.

5 Jan 2018

Novartis announces FDA approval of its first and only CML therapy with TFR data in product label

Novartis announced today that the US Food and Drug Administration (FDA) approved the inclusion of Treatment-free Remission (TFR) data in the Tasigna® (nilotinib) US product label.

26 Dec 2017

Mumps outbreak in U.S. necessitates third booster dose of vaccine for at-risk individuals

According to a federal experts panel yesterday (25th October 2017), a third dose of mumps vaccine is recommended when there is an outbreak of the viral disease. There have been several mumps outbreaks since 2006 in the United States, especially among students who have already been vaccinated before. Last year 6366 cases of the highly infectious viral infection were reported in the United States.

27 Oct 2017

Shaping the future of oncology treatment

Victories Over Cancer is about enabling those affected by cancer to enjoy more of life’s meaning full moments and making cancer more manageable. At Janssen, we're really thinking about the elimination of cancer, and we take a very deliberate approach to that.

2 Aug 2017

Measles outbreak - 35 reported deaths in Europe

Over the last 12 month, there have been 35 reported deaths due to the ongoing measles outbreak in the WHO European Region says a new report.

12 Jul 2017

'Mismatch repair' genetic defects drive cancer patient's response to immunotherapy drugs

In an expanded, three-year clinical trial of 86 patients with colorectal and 11 other kinds of cancer that have so-called 'mismatch repair' genetic defects, scientists at Johns Hopkins Medicine and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have found that half of the patients respond to an immunotherapy drug called pembrolizumab.

9 Jun 2017

Raising age limit for routine genetic testing in colorectal cancer could identify more cases of Lynch syndrome

Raising the age limit for routine genetic testing in colorectal cancer could identify more cases of families affected by Lynch syndrome, a condition that accounts for around 5% of all colon cancers, according to new research to be presented at the annual conference of the European Society of Human Genetics today (Monday).

29 May 2017