MMR News and Research

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Vascular Occlusion Risk Reviewed For CML New-Generation TKIs

A meta-analysis highlights the significantly increased risk of vascular occlusive events in patients with chronic myeloid leukaemia using some new-generation BCR-ABL tyrosine kinase inhibitors compared with use of imatinib.

17 Feb 2016

BCR–ABL transcript type linked to TKI response, outcomes

The type of BCR–ABL transcript could have an impact on tyrosine kinase inhibitor choice in patients with chronic myeloid leukaemia , according to research published in Blood.

22 Jan 2016

Maternal mortality down 44% since 1990

Maternal mortality has fallen by 44% since 1990, United Nations agencies and the World Bank Group reported today.

13 Nov 2015

New report highlights progress made in preventable maternal deaths

Maternal mortality has fallen by 44% since 1990, United Nations agencies and the World Bank Group reported today.

13 Nov 2015

Brain imaging shows how neural responses to different types of music affect emotion regulation processes

Brain imaging reveals how neural responses to different types of music really affect the emotion regulation of persons. The study proves that especially men who process negative feelings with music react negatively to aggressive and sad music.

22 Oct 2015

Chromosome 3q26.2 rearrangements linked to poor CML prognosis

Rearrangements of chromosome 3q26.2 have a significant negative impact on patients with chronic myeloid leukaemia, suggests research published in Blood.

1 Oct 2015

Vaccine exemption levels low, vaccination rates high in U.S.

Vaccine exemption levels for kindergarteners are low for most states and infant vaccination rates are high nationally, according to data from two reports published in this week's Morbidity and Mortality Weekly Report.

28 Aug 2015

PHIV children may lack immunity against measles, mumps, and rubella despite vaccination

Between one-third and one-half of individuals in the United States who were infected with HIV around the time of birth may not have sufficient immunity to ward off measles, mumps, and rubella--even though they may have been vaccinated against these diseases.

14 Aug 2015

Vascular side effects prevent first-line ponatinib use in chronic phase CML

Ponatinib is highly active when given to patients within 6 months of developing chronic phase chronic myeloid leukaemia, phase II results show, but its toxicity profile is unacceptable for first-line treatment.

7 Aug 2015

Lax state vaccination laws influence immunization and disease outbreak rates

Lax state vaccination laws contribute to lower immunization rates and increased outbreaks of preventable diseases--like whooping cough and measles--according to a new study from the University of Georgia.

6 Aug 2015

Cincinnati Children's doctors remind parents about the importance of immunizing kids before sending them to school

Doctors at Cincinnati Children's Hospital Medical Center want to remind parents about the importance of immunizing their children when preparing to send their children back to school.

28 Jul 2015

Study analyzes attitudes and practices of general physicians in different vaccination scenarios

At population level, vaccines contribute to reducing mortality associated with infectious diseases such as measles, diphtheria, tetanus, hepatitis B or bacterial meningitis.

9 Jul 2015

Researchers identify link between hormonal factors and endometrial cancer risk among women with Lynch syndrome

For women with Lynch syndrome, an association was found between the risk of endometrial cancer and the age of first menstrual cycle, having given birth, and hormonal contraceptive use, according to a study in the July 7 issue of JAMA. Lynch syndrome is a genetic condition that increases the risk for various cancers.

8 Jul 2015

PGDx introduces ImmunoSelect-R service to support development of immuno-oncology cancer therapies

Personal Genome Diagnostics, Inc., a provider of advanced cancer genome analysis and testing services, today announced the launch of its ImmunoSelect-R service designed to identify mutant neoantigens and support development of immuno-oncology cancer therapies.

1 Jun 2015

Study finds no association between MMR vaccine and increased risk of autism

In a study that included approximately 95,000 children with older siblings, receipt of the measles-mumps-rubella (MMR) vaccine was not associated with an increased risk of autism spectrum disorders (ASD), regardless of whether older siblings had ASD, findings that indicate no harmful association between receipt of MMR vaccine and ASD even among children already at higher risk for ASD, according to a study in the April 21 issue of JAMA, a theme issue on child health.

22 Apr 2015

CHLA infectious diseases specialist discusses how parents can prevent measles outbreak

Since December, there have been more than 130 confirmed cases of measles in the state of California, most of them connected to an outbreak that originated in a Southern California amusement park. Many of the infected persons were not vaccinated against the extremely contagious virus, which manifests itself through rash, fever and coughing.

6 Apr 2015

Inadequate vaccine coverage drives Disneyland measles outbreak

Inadequate vaccine coverage is likely a driving force behind the ongoing Disneyland measles outbreak, according to calculations by a research team at Boston Children's Hospital.

16 Mar 2015

Second-line bosutinib well tolerated by Japanese patients

Phase I/II clinical trial data support the use of bosutinib as second- or third-line tyrosine kinase inhibitor therapy in Japanese patients with Philadelphia chromosome-positive chronic myeloid leukaemia.

17 Feb 2015

Infectious diseases expert discusses the myths and facts about measles outbreak

Measles, a highly contagious respiratory infection that causes serious complications in about 3 of 10 people, has been grabbing headlines since last December's outbreak at Disneyland. In January, the Centers for Disease Control and Prevention reported 102 cases of measles in 14 states. One unconfirmed case was just reported in New Jersey. Measured against the approximately 600 cases reported in 2014, this year is on track to set a record for a disease that was declared eradicated in the United States in 2000.

8 Feb 2015

UAB doctor says measles can be halted with safe, effective measles vaccine

An ongoing, multistate measles outbreak linked to a California amusement park has already caused 68 confirmed cases between Jan. 1 and 23, according to the Centers for Disease Control and Prevention.

30 Jan 2015