Macrophage News and Research

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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

New technique accelerate tissue repair, reduce costs for chronic wound management

In a small clinical study, researchers administered a new method for treating chronic wounds using a novel ultrasound applicator that can be worn like a band-aid. The applicator delivers low-frequency, low-intensity ultrasound directly to wounds, and was found to significantly accelerate healing in five patients with venous ulcers.

2 Aug 2013

Researcher identify genetic mutation in Africans with HIV that puts them at higher risk for tuberculosis

A researcher from the Perelman School of Medicine at the University of Pennsylvania and colleagues have identified the genetic mutation in Africans with HIV that puts them at a much higher risk for tuberculosis (TB) infections.

25 Jul 2013

Researchers discover mechanism that prevents immune system from spinning out of control

A team led by a University of Arizona researcher has discovered a previously unknown mechanism that prevents the immune system from going into overdrive, shedding light not only on how our body controls its response to pathogens but on conditions such as autoimmune diseases, allergies and chronic inflammation as well.

24 Jul 2013

Study helps explain why some people contract bacterial super-infections

A recent study published in the July issue of the Journal of Immunology helps explain why some humans contract bacterial super-infections like pneumonia with influenza. The research was led by Le Bonheur Pediatrician-in-Chief Jon McCullers, MD - an infectious disease specialist who is also chair of the Department of Pediatrics for the University of Tennessee Health Science Center and adjunct faculty at St. Jude Children's Research Hospital.

23 Jul 2013

Animal model of human norovirus lays groundwork for developing antiviral drug treatment

An animal model of the human norovirus created at the University of Michigan Health System lays the groundwork for understanding the biology of the pesky virus and developing antiviral drug treatment.

23 Jul 2013

Scientists find that lipocalin 2 protein disables macrophages in bacterial pneumonia

Macrophages, also known as scavenger cells, play an important role in defending against bacteria and pathogens by activating inflammatory processes. In cases of lung inflammation (pneumonia) caused by pneumococcal bacteria, this important immune response function is hampered and blocked by the protein lipocalin 2.

22 Jul 2013

Monash University researchers provide novel pathways to develop treatments for diseases

Monash University researchers have gained new insight into the early stages of our immune response, providing novel pathways to develop treatments for diseases from multiple sclerosis to cancer.

22 Jul 2013

Study sheds light on how cells regenerate protective sheaths around nerve fibres in the brain

Multiple sclerosis treatments that repair damage to the brain could be developed thanks to new research.

22 Jul 2013

Scientists find way to sneak nanoparticles carrying anticancer drugs past cells of immune system

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17 Jul 2013

TSRI scientists design drug candidate that increases exercise endurance in animal models

An international group of scientists has shown that a drug candidate designed by scientists from the Florida campus of The Scripps Research Institute (TSRI) significantly increases exercise endurance in animal models.

15 Jul 2013

Cancer immunotherapies promise to be a new tool in fight against cancer

Drugs that direct a cancer patient's immune system to eradicate her or his disease, known as cancer immunotherapies, promise to be a new tool in the fight against cancer. Since the Koch Institute's inception, exploring the close relationship between the immune system and cancer has been one of the Institute's priority research areas.

9 Jul 2013

Macrophages play essential role in production of progesterone hormone

New research from the University of Adelaide shows for the first time that immune cells known as macrophages are critical to fertility by creating a healthy hormone environment in the uterus.

9 Jul 2013

MerTK inhibition in leukocytes decreases tumor growth and metastasiss

The tyrosine kinase MerTK plays a prominent role in the body's immune response. MerTK signaling helps "calm" the body's first line of immunity, the macrophage, while it performs the routine duties - clearing cells that die and healing damaged tissue.

9 Jul 2013

VBL Therapeutics publishes VB-201 pre-clinical data in journal of Atherosclerosis

VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, announced today the publication of pre-clinical data for VB-201 in the journal of Atherosclerosis.

8 Jul 2013

Researchers develop new PET tracer to better monitor the progress of cancer and cancer therapy

Imaging techniques in cancer medicine provide far more than merely information on the scale and location of cancerous ulcers. There are modern methods that additionally characterise the tumour cells precisely, for instance by specific molecules they carry on their surface. Such additional information gives doctors key clues as to the precise cancer type and enables them to predict the probability that a patient will respond to a particular form of therapy.

6 Jul 2013

New mechanism triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes

Researchers at NYU Langone Medical Center have discovered a mechanism that triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes. The results, published today in Nature Immunology, suggest a common biochemical thread to multiple diseases and point the way to a new class of therapies that could treat chronic inflammation in these non-infectious diseases without crippling the immune system.

2 Jul 2013

Increased expression of Scara1 protein might impede progression of Alzheimer's disease: Study

Identification of a protein that appears to play an important role in the immune system's removal of amyloid beta (A-beta) protein from the brain could lead to a new treatment strategy for Alzheimer's disease. The report from researchers at Massachusetts General Hospital (MGH) has been published online in Nature Communications.

2 Jul 2013

Research shows DHA found in fish oil can reduce inflammation

Bethesda, MD-Chronic inflammation is a major factor in a wide range of problems from arthritis to cardiovascular disease, and DHA (found in fish oil) is known to temper this problem. A new research report appearing in the July 2013 issue of The FASEB Journal, helps explain why DHA is important in reducing inflammation, and provides an important lead to finding new drugs that will help bring people back to optimal health.

2 Jul 2013

Men with haplogroup I of Y chromosome have 50% greater risk of developing heart disease

University of Leicester scientists have discovered a potential genetic contributor to the increased risk of heart disease among men.

18 Jun 2013

HSV-1 exploits immune system receptor to boost infectivity and cause disease

Researchers at the University of California, San Diego School of Medicine and colleagues report that the herpes simplex virus type-1 (HSV-1), which affects an estimated 50 to 80 percent of all American adults, exploits an immune system receptor to boost its infectivity and ability to cause disease.

7 Jun 2013

Macrophage News and Research

Further Reading

New technique accelerate tissue repair, reduce costs for chronic wound management

Researcher identify genetic mutation in Africans with HIV that puts them at higher risk for tuberculosis

Researchers discover mechanism that prevents immune system from spinning out of control

Study helps explain why some people contract bacterial super-infections

Animal model of human norovirus lays groundwork for developing antiviral drug treatment

Scientists find that lipocalin 2 protein disables macrophages in bacterial pneumonia

Monash University researchers provide novel pathways to develop treatments for diseases

Study sheds light on how cells regenerate protective sheaths around nerve fibres in the brain

Scientists find way to sneak nanoparticles carrying anticancer drugs past cells of immune system

TSRI scientists design drug candidate that increases exercise endurance in animal models

Cancer immunotherapies promise to be a new tool in fight against cancer

Macrophages play essential role in production of progesterone hormone

MerTK inhibition in leukocytes decreases tumor growth and metastasiss

VBL Therapeutics publishes VB-201 pre-clinical data in journal of Atherosclerosis

Researchers develop new PET tracer to better monitor the progress of cancer and cancer therapy

New mechanism triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes

Increased expression of Scara1 protein might impede progression of Alzheimer's disease: Study

Research shows DHA found in fish oil can reduce inflammation

Men with haplogroup I of Y chromosome have 50% greater risk of developing heart disease

HSV-1 exploits immune system receptor to boost infectivity and cause disease

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Expanding research and clinical options for children with cancer

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