Mad Cow Disease or BSE (bovine spongiform encephalopathy) is a progressive neurological disorder of cattle that results from infection by an unusual transmissible agent called a prion. The nature of the transmissible agent is not well understood. Currently, the most accepted theory is that the agent is a modified form of a normal protein known as prion protein. For reasons that are not yet understood, the normal prion protein changes into a pathogenic (harmful) form that then damages the central nervous system of cattle.
Infectious proteins called prions cause a group of related, fatal and incurable neurodegenerative disorders, including bovine spongiform encephalopathy or Mad Cow disease and Creutzfeldt-Jakob disease, both of which affect humans.
Chronic wasting disease of the deer or CWD has been nicknamed “Zombie deer disease”. It has been affecting deer across Pennsylvania and has also been noted in Lancaster County.
Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. The infectious, misfolded protein particles often go undetected as they destroy brain tissue, causing memory loss, mobility issues, and ultimately death.
Researchers have found that surgical instruments used for neurosurgery could get contaminated by the altered brain proteins that are seen in Alzheimer’s disease. These instruments are capable of spreading the condition if not treated or decontaminated properly before reuse. The study results were published in the latest issue of the journal Nature.
A recent study has found that prion proteins that cause a deadly brain disease may enter the body via the eyes.
Prion diseases affect the brain, causing neurodegenerative problems that always lead to death. They attracted attention in the late 1990s due to the "Mad Cow" scare.
Scotland has confirmed its first case of Mad Cow disease or Bovine Spongiform Encephalopathy (BSE) since 2018 on a cattle farm. The case was confirmed after a cow died.
A new study has shed light on the mechanisms underlying the progression of prion diseases and identified a potential target for treatment.
Researchers from the Verstreken lab have identified a completely novel function for Hsp90, one of the most common and most studied proteins in our body.
Plastic surgery patients were getting infections with antibiotic resistant bacteria, and no one knew why. UConn microbiologists found the answer in a leech's gut. Their research, published today in mBio, provides proof that tiny levels of antibiotics found in the environment can encourage bacterial resistance.
Chronic wasting disease did not cross the species barrier to infect cynomolgus macaque monkeys during a lengthy investigation by National Institutes of Health scientists exploring risks to humans.
Scientists at the University of Alberta may have found possible targets for therapeutic interventions in the fight against Lou Gehrig's disease.
Postnova Analytics reports that the Department of Molecular Biology & Biotechnology at the University of Sheffield is using their AF2000 Field Flow Fractionation system to investigate the mechanism of amyloid formation, a protein mis-folding process implicated to be the cause of Alzheimer’s and other neurodegenerative diseases.
Creutzfeldt-Jakob disease (CJD)- the human equivalent of mad cow disease- is caused by rogue, misfolded protein aggregates termed prions, which are infectious and cause fatal damages in the patient's brain. CJD patients develop signature microscopic sponge-like holes in their brains.
Research carried out at the University of Kent has the potential to influence the future search for treatment of neurodegenerative diseases that are linked to a family of protein molecules known as 'amyloid'.
A new kind of antibody targets a feature shared by proteins thought to cause the most damage in Alzheimer's disease, Parkinson's disease, and related conditions, creating potential for a unified treatment approach.
Recent research on Parkinson's disease has focused on the gut-brain connection, examining patients' gut bacteria, and even how severing the vagus nerve connecting the stomach and brain might protect some people from the debilitating disease.
A new study has uncovered a molecular mechanism in the prion protein, a protein responsible for neurodegenerative diseases, which may explain why nerve cells degenerate in these disorders.
Prion diseases are scary, incurable and fatal. They first gained notoriety when cows became infected by prion proteins and, in turn, infected people. Fervor surrounding mad cow disease resulted in the U.S. banning imports of beef from the European Union for 15 years.
The highly pathogenic Staphylococcus aureus bacteria is one of the five most common causes of hospital-acquired infections. In the US alone, approximately 500,000 patients at hospitals contract a staph infection. It is the bacteria responsible for MRSA, for which there is no vaccine.