Malaria

Malaria is a mosquito-borne disease caused by a parasite called Plasmodium. When infected mosquitoes bite the human body, the parasites multiply in the liver and then infect red blood cells. Even though this potentially fatal disease can be prevented and cured, each year 350-500 million cases of malaria still occur worldwide, and over one million people die.

The Effect of Climate Change on Malaria

In commemoration of World Malaria Day, 2021, we look at the relationship between malaria transmission and climate change.

What is Malaria?

Malaria Causes

World Malaria Day 2021: An interview with Sir Brian Greenwood

Malaria Mechanism

Malaria Diagnosis

Malaria Prevention

World Malaria Day 2021: Finding new approaches to fight malaria

Malaria Treatment

Malaria Epidemiology

Malaria History

Fighting malaria in 2021: Where are we now and where are we going?

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Malaria Society And Culture

Malaria Symptoms

Malaria: A Force Shaping Blood Cell Evolution?

What is Cerebral Malaria?

Driving the Self-Destruction of Malaria-Transmitting Mosquitos

The Science Behind Why Mosquitoes Prefer to Bite Certain People

Latest Malaria News and Research

Global disease burden study highlights COVID-19 impact and health inequities

Rates of early death and poor health caused by HIV/AIDS and diarrhea have been cut in half since 2010, and the rate of disease burden caused by injuries has dropped by a quarter in the same time period, after accounting for differences in age and population size across countries, based on a new study published in The Lancet. The study measures the burden of disease in years lost to early death and poor health.

17 Apr 2024

Oxford University and Brazil partner to advance malaria vaccine development

Professor Sue Ann Costa Clemens CBE, Chair of Global Health at the Department of Paediatrics and Head of Oxford Latam Research Group - a collaboration between Oxford and Brazil, aimed at strengthening our commitment to global health - met with His Excellency Antonio Patriota, Brazilian Ambassador to the UK, to discuss the co-development of a Malaria vaccine and advance public health outcomes in Brazil.

10 Apr 2024

Pioneering study launched to examine how the immune system responds to repeated malaria infections

Scientists at the University of Oxford and the University of Edinburgh have launched a pioneering study that examines how the immune system responds to repeated malaria infections.

10 Apr 2024

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

7 Apr 2024

UC San Diego researchers discover genetic connections to alcohol consumption

A research group centered at the University of California San Diego School of Medicine has drilled deep into a dataset of over 3 million individuals compiled by the direct-to-consumer genetics company 23andMe, Inc., and found intriguing connections between genetic factors influencing alcohol consumption and their relationship with other disorders.

5 Apr 2024

Global life expectancy rises by 6.2 years since 1990 despite COVID-19 setbacks

Global life expectancy increased by 6.2 years since 1990 according to a new study published in The Lancet.

3 Apr 2024

New malaria vaccine strain shows promise in preclinical trials

In a report published on March 21, 2024 in EMBO Molecular Medicine (A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion) investigators at Seattle Children's Research Institute and Sanaria Inc. describe the development of a whole malaria parasite vaccine strain that infects the liver, develops to the late liver stage, and then gets completely stuck and cannot burst out of the liver to cause symptomatic blood infection.

2 Apr 2024

Ministers of Health commit to accelerated action against malaria in Africa

Ministers of Health from African countries with the highest burden of malaria committed today to accelerated action to end deaths from the disease.

1 Apr 2024

WHO recommends R21/Matrix-M vaccine for malaria prevention in children

The World Health Organization (WHO) has recommended a new vaccine, R21/Matrix-M, for the prevention of malaria in children.

27 Mar 2024

New genetic system analyzes the underlying mechanisms of CRISPR-based DNA repair outcomes

Since its breakthrough development more than a decade ago, CRISPR has revolutionized DNA editing across a broad range of fields.

26 Mar 2024

Routine genomic surveillance at antenatal care can be a cost-effective approach to detect changes in malaria transmission

Genetic diversity of the malaria parasite in pregnant women and children declined in an area targeted for malaria elimination in Mozambique, according to a study led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by "la Caixa" Foundation and the Manhiça Health Research Centre (CISM).

20 Mar 2024

How is climate change influencing the spread of vector-borne diseases?

The impact of climate change, weather, and other anthropogenic factors on vector-borne illness spread globally.

18 Mar 2024

Study highlights growing burden of neurological disorders worldwide

Globally, the number of people living with, or dying from, neurological conditions such as stroke, Alzheimer's disease and other dementias, and meningitis has risen substantially over the past 30 years due to the growth and aging of the global population as well as increased exposure to environmental, metabolic, and lifestyle risk factors.

15 Mar 2024

Innovative approaches needed to overcome health system barriers in malaria vaccination

The current literature to investigate the challenges malaria vaccination faced in reaching high-risk children.

15 Mar 2024

Acute malnutrition raises risk of malaria treatment failure in young children

Children with acute malnutrition across Africa and Asia have a higher risk of treatment failure and malaria reinfection, even after being given the best currently available and recommended malaria treatment.

13 Mar 2024

T1-spanin breakthrough offers new hope against antibiotic resistance

Given the worldwide prevalence of drug-resistant bacteria, the research fraternity is on the lookout for alternative bactericidal treatment approaches.

12 Mar 2024

"Copy-paste" genetic mechanism increases the genetic diversity of malaria parasite

By dissecting the genetic diversity of the most deadly human malaria parasite – Plasmodium falciparum – researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) have identified a mechanism of 'copy-paste' genetics that increases the genetic diversity of the parasite at accelerated time scales.

7 Mar 2024