Malignant News and Research

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Investigational device to treat brain cancer shows promise in early studies

New early data showed that an investigational device that specifically targets rapidly growing cancer cells with intermediate frequency electrical fields -- called Tumor-Treating Fields (TTFields) -- more than doubled the median overall survival rates in patients with recurrent glioblastoma multiforme (GBM), the most common and aggressive type of malignant brain tumor.

30 May 2007

Dentists need more training in oral cancer detection

More than 92 percent of Illinois dentists provide oral cancer examinations for their patients, but many are not performing the procedures thoroughly or at optimum intervals, according to a new University of Illinois at Chicago study.

30 May 2007

Stem cells may look malignant, not act it

Call it the cellular equivalent of big glasses, a funny nose and a fake mustache.

24 May 2007

Tool will revolutionise functional genomic studies in clostridia

The genome of the organism that produces the world's most lethal toxin has been revealed.

24 May 2007

Breast MRI may have a role in evaluation of newly diagnosed breast cancers

Among women who are newly diagnosed with breast cancer, magnetic resonance imaging (MRI) of the breast appears helpful in determining surgical treatment, according to a report in the May issue of Archives of Surgery, one of the JAMA/Archives journals.

22 May 2007

Patients with myelodysplastic syndromes treated with Revlimid are living longer and remaining transfusion independent

New updated results from a pivotal Phase II trial evaluating Revlimid in patients with an incurable blood cancer known as myelodysplastic syndromes (MDS) were presented by Dr. Alan List, from the H. Lee Moffitt Cancer Center & Research Institute, at the 9th International Symposium on MDS currently taking place in Florence, Italy.

18 May 2007

Chromium 6 in drinking water may cause cancer

Researchers announced today that there is strong evidence a chemical referred to as hexavalent chromium, or chromium 6, causes cancer in laboratory animals when it is consumed in drinking water.

17 May 2007

Promoter hypermethylation is common in breast cancer

Cancer epidemiologists at the University at Buffalo have identified specific genes that are most likely to become cancer promoters when exposed to a process called DNA promoter hypermethylation.

17 May 2007

Mount Sinai uses breakthrough treatment for spinal cancer

The Mount Sinai Medical Center is the only hospital in New York City using the Novalis Shaped Beam Surgery System on spinal cancer.

16 May 2007

Researchers identify genetic markers associated with breast cancer tumor grade and lymph node metastases

Researchers have identified genetic markers on several chromosomes in the tissue surrounding tumor cells that are associated with breast cancer tumor grade and the presence of lymph node metastases, according to a study in the May 16 issue of JAMA.

16 May 2007

Gene p53 thought to assist chemotherapy may help cancer thrive

A gene thought to be essential in helping chemotherapy kill cancer cells, may actually help them thrive.

16 May 2007

Cells that cause Ewing's sarcoma identified

Inserm researchers at the Institut Curie have identified the cells that cause Ewing’s sarcoma.

16 May 2007

Primary tumors can chose different strategies to spread and form metastases

Primary tumors can spread towards distant organs as single cells, when they lose a protein called E-cadherin.

16 May 2007

Specific genes identified that are most likely to become cancer promoters when exposed to DNA promoter hypermethylation

Hypermethylation is a process that causes genes that promote normal cell growth to produce proteins that cause malignant behavior, or unregulated cell growth. Until now, data has been very limited regarding the mechanism and causes of hypermethylation, especially for hypermethylation in breast cancer.

15 May 2007

Scientists target cancer cells with nanotechnology

A team of Australian scientists have developed a way to deliver lethal drug doses to tumours without causing side-effects, such as nausea and hair loss.

14 May 2007

Swedish 'snus' linked to a doubled risk of pancreatic cancer

People who use Swedish moist snuff (snus) run twice the risk of developing cancer of the pancreas.

11 May 2007

African-Americans and Asian-Americans need to check their feet for signs of skin cancer

Many people don't know that the Jamaican musician, Bob Marley died of malignant melanoma in his right foot.

10 May 2007

The financial impact of a brain tumor diagnosis on patients and families

A new study released by the National Brain Tumor Foundation, The Financial Impact of a Brain Tumor Diagnosis on Patients and Families, reveals that the financial impact for patients suffering from brain tumors is devastating and life-changing.

10 May 2007

Review of six large-scale clinical trials of aliskiren

Hypertension is a serious condition affecting millions.Currently there are seven classes of drugs used to reduce blood pressure. Aliskiren (Tekturna , Rasilez) is the first of a new class of orally active antihypertensive drugs that works by inhibiting renin.

10 May 2007