Mammary Gland News and Research

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Immune response to mRNA COVID vaccines delayed in pregnant women

Researchers in the United States have conducted comprehensive profiling of humoral immune responses in pregnant, lactating, and non-pregnant women following coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccination to probe differences in vaccine-induced immunity.

25 Oct 2021

Hormone-resistant prostate, breast cancers added to clinical trial of experimental DNA therapy

The Republic of Belarus Ministry of Health has approved expanding the ongoing clinical trial of CureLab Oncology's Elenagen, an experimental DNA therapy, to include two new arms: 1) hormone-resistant breast cancer; and 2) hormone-resistant metastatic prostate cancer.

3 Aug 2021

Mechanical factors play a key role in the natural growth of human organs

In addition to chemical factors, mechanical influences play an important role in the natural growth of human organs such as kidneys, lungs and mammary glands - but also in the development of tumors.

13 Jul 2021

Researchers unravel cellular mechanisms driving the initiation of mammary gland development

Helsinki University research group used live tissue imaging for the first time to visualize the emergence of the mammary gland.

21 Jun 2021

Study shows that breast cancer can be prevented with better contraception choices

Hormonal contraceptives, e.g. the pill, the patch, and the vaginal ring, contain synthetic hormones that prevent pregnancy by either stopping ovulation, changing the cervical mucus to stop sperm from passing through the cervix and finding an egg, or changing the womb's lining to prevent a fertilized egg from being implanted in it.

29 May 2021

Incorrect DNA packaging makes retrotransposons more accessible

Scientists led by Dr. Salvador Aznar-Benitah, head of the Stem Cells and Cancer laboratory at IRB Barcelona, have described the alterations that occur during mammary gland formation when heterochromatin (the part of DNA that does not actively produce proteins) is poorly regulated.

18 May 2021

YAP inhibitors could facilitate targeted treatment of basal-like breast cancer

Targeted treatment of basal-like breast cancer could be facilitated by YAP inhibitors in the future. As reported by an MDC team headed by Walter Birchmeier in the scientific journal Cancer Research, this type of cancer requires the support of the YAP protein to stimulate the growth of cancer stem cells.

22 Mar 2021

Propylparaben exposure during pregnancy may lessen protection against breast cancer

Low doses of propylparaben - a chemical preservative found in food, drugs and cosmetics - can alter pregnancy-related changes in the breast in ways that may lessen the protection against breast cancer that pregnancy hormones normally convey, according to University of Massachusetts Amherst research.

16 Mar 2021

Cooperation between two key genes drives breast cancer growth

Cooperation is generally a good thing -- working together to reach a goal. But in the case of cancer, it can be detrimental. University of Cincinnati researchers have discovered that cooperation between two key genes drives cancer growth, spread and treatment resistance in one particularly aggressive type of breast cancer.

9 Mar 2021

New 'E-Morph' test method replaces animal experiments to detect hormone-like effects

Endocrine disruptors (EDs) are hormone-like substances that can have undesirable effects on health. For example, chemicals can increase the risk of breast cancer if they act in a manner similar to the female sex hormone estrogen.

26 Feb 2021

Pulmonary hypertension drug may become a treatment option for cancer

A drug used to treat pulmonary hypertension significantly reduced the capacity of tumor cells to migrate and invade other tissues in trials involving pancreatic, ovarian, breast cancer, and leukemia cell lines.

15 Dec 2020

Researchers report the discovery of innate immune signaling pathway in fibroblasts

Vanderbilt University researchers have reported the counterintuitive discovery that certain chemotherapeutic agents used to treat tumors can have the opposite effect of tissue overgrowth in normal, intact mammary glands, epidermis and hair follicles.

16 Oct 2020

Oxygen-deprived breast cancer cells send out messages that promote cancer progression

According to a study by The Wistar Institute, breast cancer cells starved for oxygen send out messages that induce oncogenic changes in surrounding normal epithelial cells.

11 Aug 2020

Researchers identify two dozen pesticides linked with mammary gland tumors

In an analysis of how regulators review pesticides for their potential to cause cancer, researchers at Silent Spring Institute identified more than two dozen registered pesticides that were linked with mammary gland tumors in animal studies.

4 Aug 2020

Pasteurization of breast milk inactivates novel coronavirus

Pasteurizing breast milk using a common technique inactivates severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) making it safe for use, according to new research in CMAJ.

9 Jul 2020

Female reproductive organs not susceptible to direct SARS-CoV-2 infection

Researchers at the University in San Francisco, California, report that coronavirus disease 2019 (COVID-19) is unlikely to negatively impact on pregnancy-related outcomes such as premature birth, transmission to babies via breast milk, and infertility.

23 Jun 2020

Researchers identify determining factor in luminal cancer cells

The Translational Control of Cell Cycle and Differentiation Lab at IRB Barcelona, led by ICREA researcher Raúl Méndez, has published a study in the journal Science Advances that has identified a key factor in the development of luminal breast cancer.

18 May 2020

Discovery of new type of immune cell in breast ducts

Australian researchers from Walter and Eliza Hall Institute have discovered a new form of immune cells within the ducts of the breast that keeps the breasts healthy. The study was published this week in the journal Nature Cell Biology.

27 Apr 2020

Study reveals new role for a triple-negative breast cancer target

Unlike almost every other organ, the mammary gland does not develop until after birth. And it's unusually dynamic, shape-shifting during menstrual cycles, puberty, pregnancy, and lactation.

19 Dec 2019

Hair dyes raise the risk of breast cancers especially among black women says study

A new study has confirmed that permanent hair dyes and chemical hair straightener use are associated with breast cancers especially among African American women. There have been animal studies that reveal that these hair dyes and chemicals used for straightening the hair are associated with cancers. Human studies however have not shown consistent results establishing the relationship between the chemicals and the cancers.

5 Dec 2019