Mania News and Research

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Modafinil under study for bipolar disorder

A preliminary study of 85 patients with bipolar disorder shows that a drug used to treat patients with sleep disorders might also control the depressive symptoms associated with bipolar disorder.

3 Aug 2007

Bipolar disorder shrinks the brain

British researchers have found that people who suffer from manic depression or bipolar disorder as it is more often called, also experience a loss of brain tissue and an accelerated shrinking of their brain.

21 Jul 2007

Bipolar disorder linked to reduction in brain tissue

People with bipolar disorder or manic depression suffer from an accelerated shrinking of their brain, researchers at the University of Edinburgh have found.

20 Jul 2007

Study to evaluate lithium for the treatment of bipolar disorder

Researchers at the University of Illinois at Chicago are participating in a national study to evaluate lithium for the treatment of bipolar disorder in children and adolescents.

18 Jul 2007

Novel type of communication between nerve cells in the brain discovered

The findings may have relevance for the prevention and treatment of epilepsy, and possibly in the exploration of other aspects of brain functions, from creative thought processes to mental illnesses such as schizophrenia.

17 Jul 2007

Novel pathways and markers for diagnosis and treatment of bipolar disorder

Looking into the brain is yielding vital clues to understanding, diagnosing and treating bipolar disorder, according to findings being presented at the Seventh International Conference on Bipolar Disorder.

8 Jun 2007

Antipsychotic drugs used to treat dementia shorten life

A new Canadian study by a geriatric medicine specialist has found that the antipsychotic drugs used to treat some of the disruptive behaviours of older adults with dementia may shorten the patient's life.

5 Jun 2007

Bipolar disorder - the clue may be in the genes

The first scan of the entire human genetic code has revealed that developing bipolar disorder may to some extent depend on the combined effects of variations in many different genes in the brain, none of which is powerful enough to cause the disease by itself.

9 May 2007

4 percent of US adults have some form of bipolar disorder

Approximately 4.4 percent of U.S. adults may have some form of bipolar disorder during some point in their lifetime, including about 2.4 percent with a "sub-threshold" condition, according to an article in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

8 May 2007

Bipolar disorder may be more accurately characterized as a spectrum disorder

A new study supports earlier estimates of the prevalence of bipolar disorder in the U.S. population, and suggests the illness may be more accurately characterized as a spectrum disorder.

8 May 2007

Childhood-onset bipolar disorder is more common than believed

In bipolar disorder, also called manic-depressive disorder, a person experiences mood changes that fluctuate between periods of abnormally high energy and extreme depression.

2 May 2007

FDA approves INVEGA treatment for schizophrenia

The U.S. Food and Drug Administration (FDA) has approved INVEGA (paliperidone) Extended-Release Tablets, a new once-daily, atypical antipsychotic, for the long-term maintenance treatment of schizophrenia.

30 Apr 2007

Difficult to distinguish bipolar symptoms in children

At least one-third of the time, the symptoms of bipolar disorder first appear in childhood or adolescence.

26 Apr 2007

Lithium increases gray matter in bipolar brains

Neuroscientists at UCLA have shown that lithium, long the standard treatment for bipolar disorder, increases the amount of gray matter in the brains of patients with the illness.

11 Apr 2007

Intensive psychotherapy most effective for treating bipolar depression

Patients taking medications to treat bipolar disorder are more likely to get well faster and stay well if they receive intensive psychotherapy, according to results from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD), funded by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH).

4 Apr 2007

Treatment options for bipolar disorder

For depressed people with bipolar disorder who are taking a mood stabilizer, adding an antidepressant medication is no more effective than a placebo (sugar pill), according to results published online on March 28, 2007 in the New England Journal of Medicine.

1 Apr 2007

Circadian genes may be involved in bipolar disorder

Disrupt the gene that regulates the biological clocks in mice and they become manic, exhibiting behaviors similar to humans with bipolar disorder, UT Southwestern Medical Center researchers have found.

25 Mar 2007

Schizophrenia drug to be used to treat autism

A drug normally used to treat schizophrenia has been given approval by the U.S. the Food and Drug Administration for use in treating the symptoms of autism in children and adolescents.

9 Oct 2006

SSRIs associated with severe violence in a small number of individuals

Use of one class of antidepressant drugs, the SSRIs (selective serotonin reuptake inhibitors), may be associated with severe violence in a small number of individuals say the authors of paper published in PLoS Medicine.

12 Sep 2006

Bipolar disorder costs twice as much in lost productivity as major depressive disorder

Bipolar disorder costs twice as much in lost productivity as major depressive disorder, a study funded by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) has found. Each U.S. worker with bipolar disorder averaged 65.5 lost workdays in a year, compared to 27.2 for major depression.

4 Sep 2006