Mania News and Research

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Age and onset age may influence bipolar treatment response

Some differences in treatment response emerge when patients with bipolar disorder are grouped according to their age and their age at bipolar onset, say researchers.

14 May 2014

Life events link to mania bolstered

Study findings support a role for childhood and adulthood stressors in the risk of both new-onset and recurrent mania.

8 May 2014

Smartphone app shows promise for detecting early signs of mood changes in people with bipolar disorder

A smartphone app that monitors subtle qualities of a person's voice during everyday phone conversations shows promise for detecting early signs of mood changes in people with bipolar disorder, a University of Michigan team reports.

8 May 2014

Migraine a depressing issue in bipolar disorder

Patients with bipolar disorder have a markedly increased prevalence of migraine, report researchers.

1 May 2014

Forest Laboratories, Richter report positive results from cariprazine Phase IIb trial for bipolar depression

Forest Laboratories, Inc. and Gedeon Richter Plc. today announced positive topline results from a Phase IIb trial evaluating the efficacy and safety of the investigational antipsychotic cariprazine in patients with bipolar depression.

31 Mar 2014

EEG findings specific to mood state in bipolar disorder

The electrical activity of the brain differs in patients with bipolar disorder according to whether they are experiencing a manic or depressed phase, research shows.

27 Mar 2014

Bidirectional link between life events and mood episodes

The link between life events and mood episodes in patients with bipolar disorder is bidirectional, with positive and negative life events having different effects, report researchers.

27 Mar 2014

Six dimensions explain mania symptom variability

Researchers have identified a six-factor latent structure that they say best describes the symptomatology of hospitalized patients with bipolar mania.

21 Mar 2014

Distinct motor activity patterns for bipolar depression and mania

Acutely ill patients with bipolar disorder show distinct differences in motor activity regulation during episodes of mania and depression, research indicates.

13 Mar 2014

BDNF abnormalities may predict bipolar disorder

Patients with bipolar disorder show abnormalities in the conversion of pro-brain derived neurotrophic factor to the mature form, which may be used to aid diagnosis of the condition.

28 Feb 2014

Pregnant women with bipolar disorder more frequently have mental health

Pregnant and postpartum women with bipolar disorder more frequently have significant mental health and early mothering challenges than other perinatal women undergoing psychiatric treatment, according to a study in the Journal of Affective Disorders.

25 Feb 2014

Comorbid OCD and bipolar disorder should be treated as mood disorder

Most patients with both bipolar disorder and obsessive–compulsive disorder should be treated as having bipolar disorder, researchers suggest.

21 Feb 2014

Consistent mania monitoring during perinatal period warranted

Pregnant and postpartum women with bipolar disorder experience clinically severe symptoms, suggesting the need for continued monitoring of mania during this time, say researchers.

13 Feb 2014

Rhythmicity of activity linked to bipolar mania

Circadian rhythm disturbances are associated with bipolar disorder, and particularly with mania, indicate study findings.

12 Feb 2014

Forest Laboratories third quarter net sales increase 24.9% to $846.8 million

Forest Laboratories, Inc., a leading, fully integrated, specialty pharmaceutical company largely focused on the United States market, announced that reported diluted earnings per share equaled $0.07 in the third quarter of fiscal 2014, compared to a reported loss per share of ($0.58) in the third quarter of fiscal 2013. The third quarter of fiscal 2014 included a $45 million charge ($28.2 million net of tax) related to Project Rejuvenate.

21 Jan 2014