Manic Depression News and Research

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UCI researchers uncover new underlying factor of seizures

University of California, Irvine researchers with the School of Medicine have identified the mechanism by which valproic acid controls epileptic seizures, and by doing so, also revealed an underlying factor of seizures.

15 Sep 2015

FDA accepts sNDA to review Brintellix clinical trial data for treatment of major depressive disorder

Takeda Pharmaceutical Company Limited (Takeda) and H. Lundbeck A/S (Lundbeck) announced today the U.S. Food and Drug Administration (FDA) has accepted a supplemental New Drug Application (sNDA) for review to add clinical data regarding the effect of Brintellix (vortioxetine) on certain aspects of cognitive function in adults with Major Depressive Disorder (MDD) to the current product label.

11 Aug 2015

Greater evidence-based help needed for depressed workers - New report from The Work Foundation

A report from Lancaster University’s Work Foundation recommends that in order to improve both productivity and health and wellbeing among those of working age, more concerted action must be taken to support people with depression to stay in and to return to work...

21 May 2015

Tal Medical raises $14 million funding round from new and existing investors

Tal Medical, a clinical-stage medical device company developing a new treatment for depression and other psychiatric disorders, today announced a $14 million funding round from existing investor PureTech, a new institutional investor, and several prominent individual investors.

21 Apr 2015

Errors in medication common on admission to mental health services, shows study

A recent study, published in the International Journal of Clinical Pharmacy, involving Aston University (UK), South Essex Partnership University NHS Foundation Trust (SEPT) and the University of East Anglia (UK) found medication errors were common on admission to mental health services.

16 Nov 2013

Longer looks: Gunshot season for surgeons; Hispanic teen suicide; the economics of pregnancy

Every week reporter Ankita Rao selects interesting reading from around the Web.

23 Aug 2013

Viewpoints: Baker and Dingell urge efforts to cut gun deaths; Doctors as union workers

Gun violence now rivals traffic accidents as the leading cause of death by injury in the United States. Quite simply, gun violence threatens to overwhelm us. Americans are grappling for strategies to make sure that the horror that occurred in Newtown isn't repeated.

31 Jan 2013

Elan commences ELND005 Phase 2 study in Bipolar I Disorder

Transition Therapeutics Inc. today announced that its licensing partner, Elan Corporation, plc has commenced a Phase 2, placebo-controlled, safety and efficacy study of oral ELND005 as an adjunctive maintenance treatment in patients with Bipolar I Disorder (BPD 1) to delay the time to occurrence of mood episodes.

31 Aug 2012

Elan commences ELND005 Phase 2 study in Bipolar I Disorder

Elan Corporation, plc today announced that it has commenced a Phase 2, placebo-controlled, safety and efficacy study of oral ELND005 as an adjunctive maintenance treatment in patients with Bipolar I Disorder (BPD 1) to delay the time to occurrence of mood episodes.

30 Aug 2012

New evidence reveals possibility of mood-enhancing effects associated with some flavors

New evidence reveals the possibility of mood-enhancing effects associated with some flavors, stemming at least in part from natural ingredients bearing a striking chemical similarity to valproic acid, a widely used prescription mood-stabilizing drug, scientists reported here today. This effect joins those previously reported for chocolate, teas and some other known comfort foods.

20 Aug 2012

Key risk features predictive for suicide in bipolar disorder identified

Study findings suggest that patients with bipolar disorder who present with mixed-states, melancholic depressive features, or have multiple antidepressant treatment episodes are at increased risk for suicide.

13 Jul 2012

iPSYCH project to study five specific mental disorders

Is it possible to prevent the development of schizophrenia? Can certain patients develop autism if they carry a specific gene and have been exposed to a viral fetal infection? Should all ADHD patients take the same type of medication? This unique research project will try to answer these questions. The project is based at Aarhus University and will be known as 'The Lundbeck Foundation's Initiative for Integrative Psychiatric Research.'

20 Mar 2012

DBS safe and effective for treatment-resistant depression in patients with unipolar MDD or BP

A new study shows that deep brain stimulation (DBS) is a safe and effective intervention for treatment-resistant depression in patients with either unipolar major depressive disorder (MDD) or bipolar ll disorder.

3 Jan 2012

CNVs appear to play a significant role in early onset bipolar disorder

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, reports that abnormal sequences of DNA known as rare copy number variants, or CNVs, appear to play a significant role in the risk for early onset bipolar disorder.

22 Dec 2011

Study shows new biochemical disturbances in the brains of children with ADHD

A new study at örebro University in Sweden shows that children with ADHD have nearly 50 percent less of a protein that is important for attention and learning. The finding may mean that there are other biochemical disturbances in the brains of individuals with ADHD than was previously believed.

5 Dec 2011

Common DNA variations contribute to schizophrenia, bipolar disorder

A team of over 250 researchers from more than 20 countries have discovered that common genetic variations contribute to a person's risk of schizophrenia and bipolar disorder.

20 Sep 2011

Scientists discover common genetic variants associated with schizophrenia and bipolar disorder

Common genetic variants contribute to the risk of schizophrenia and bipolar disorder, an international research consortium has discovered.

19 Sep 2011

Landmark international study confirms common genetic contribution to mental illness

An international research consortium has confirmed that common genetic variants contribute to a person’s risk of schizophrenia and bipolar disorder. The largest study of its kind provides new molecular evidence that 11 regions have strong association with these diseases, including six regions not previously observed. The researchers also found that many of these DNA variations contribute to both diseases. The findings, reported by the Psychiatric Genome-Wide Association Study Consortium (PGC) and published online in two papers in the journal Nature Genetics, represent significant advances in the understanding the causes of these severe and often debilitating disorders.

18 Sep 2011

New stem cell lines help study genetic, biological underpinnings of bipolar disorder

New stem cell lines developed from the skin of adults living with bipolar disorder are providing researchers at the University of Michigan Health System an unprecedented opportunity to delve into the genetic and biological underpinnings of the devastating mood disorder.

24 Aug 2011

Brain areas responsible for motor behavior might represent therapeutic targets for bipolar disorder

A new study by motor control and psychology researchers at Indiana University suggests that postural control problems may be a core feature of bipolar disorder, not just a random symptom, and can provide insights both into areas of the brain affected by the psychiatric disorder and new potential targets for treatment.

25 May 2011

Manic Depression News and Research

UCI researchers uncover new underlying factor of seizures

FDA accepts sNDA to review Brintellix clinical trial data for treatment of major depressive disorder

Greater evidence-based help needed for depressed workers - New report from The Work Foundation

Tal Medical raises $14 million funding round from new and existing investors

Errors in medication common on admission to mental health services, shows study

Longer looks: Gunshot season for surgeons; Hispanic teen suicide; the economics of pregnancy

Viewpoints: Baker and Dingell urge efforts to cut gun deaths; Doctors as union workers

Elan commences ELND005 Phase 2 study in Bipolar I Disorder

Elan commences ELND005 Phase 2 study in Bipolar I Disorder

New evidence reveals possibility of mood-enhancing effects associated with some flavors

Key risk features predictive for suicide in bipolar disorder identified

iPSYCH project to study five specific mental disorders

DBS safe and effective for treatment-resistant depression in patients with unipolar MDD or BP

CNVs appear to play a significant role in early onset bipolar disorder

Study shows new biochemical disturbances in the brains of children with ADHD

Common DNA variations contribute to schizophrenia, bipolar disorder

Scientists discover common genetic variants associated with schizophrenia and bipolar disorder

Landmark international study confirms common genetic contribution to mental illness

New stem cell lines help study genetic, biological underpinnings of bipolar disorder

Brain areas responsible for motor behavior might represent therapeutic targets for bipolar disorder

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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