Marfan Syndrome News and Research

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Marfan syndrome is a condition in which your body's connective tissue is abnormal. Connective tissue helps support all parts of your body. It also helps control how your body grows and develops. Marfan syndrome most often affects the connective tissue of the heart and blood vessels, eyes, bones, lungs, and covering of the spinal cord. Because the condition affects many parts of the body, it can cause a number of complications. In some cases, the complications are life threatening.

Marfan syndrome is a genetic disorder. A mutation, or change, in the gene that controls how the body makes fibrillin causes Marfan syndrome. Fibrillin is a protein that plays a major role in your body’s connective tissue. Most people who have Marfan syndrome inherit it from their parents. If you have Marfan syndrome, you have a 50 percent chance of passing the altered gene on to each of your children. In about 1 in 4 cases, Marfan syndrome occurs because of a spontaneous mutation. Thus, the affected person is the first in their family to have the condition.
Research points to causes, potential treatment approaches for systemic sclerosis

Research points to causes, potential treatment approaches for systemic sclerosis

Key findings may have broad implications for future scleroderma therapy

Key findings may have broad implications for future scleroderma therapy

Scientists study genetic factors involved in complex diseases

Scientists study genetic factors involved in complex diseases

Common blood pressure drug reduces fatal cardiac problem in patients with Marfan syndrome

Common blood pressure drug reduces fatal cardiac problem in patients with Marfan syndrome

Faulty genetic pathway is a potent player in many types of allergies, say researchers

Faulty genetic pathway is a potent player in many types of allergies, say researchers

Researchers to develop new diagnostic tools and treatments for people with rare diseases

Researchers to develop new diagnostic tools and treatments for people with rare diseases

Tall, thin women face increased risk of infection with nontuberculous mycobacteria

Tall, thin women face increased risk of infection with nontuberculous mycobacteria

Institute for Translational Medicine and Therapeutics' 2012 symposium be held from Oct. 16-17

Institute for Translational Medicine and Therapeutics' 2012 symposium be held from Oct. 16-17

Johns Hopkins team creates synthetic protein that can help locate tumors

Johns Hopkins team creates synthetic protein that can help locate tumors

National Marfan Foundation’s annual conference to be held in Chicago

National Marfan Foundation’s annual conference to be held in Chicago

Marfan syndrome researcher to receive March of Dimes/Colonel Harland Sanders Award

Marfan syndrome researcher to receive March of Dimes/Colonel Harland Sanders Award

Researchers pinpoint source of Loeys-Dietz syndrome

Researchers pinpoint source of Loeys-Dietz syndrome

Losartan may help prevent smoking-related COPD

Losartan may help prevent smoking-related COPD

Children can have successful surgical repairs for hollow or sunken chest

Children can have successful surgical repairs for hollow or sunken chest

Common genetic variant may predispose people to acute dissections

Common genetic variant may predispose people to acute dissections

Bedside screening tool can help diagnose acute aortic dissection

Bedside screening tool can help diagnose acute aortic dissection

Losartan therapy improves muscle injury regeneration and prevents disuse atrophy

Losartan therapy improves muscle injury regeneration and prevents disuse atrophy

Animal studies reveal new route to treating heart disease

Animal studies reveal new route to treating heart disease

Scientists discover new clues about mechanism behind losartan drug's protective effects

Scientists discover new clues about mechanism behind losartan drug's protective effects

Losartan improves effectiveness of nanotherapeutics against cancer

Losartan improves effectiveness of nanotherapeutics against cancer