Mast Cell News and Research

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Researchers study how allergens get on our nerves to drive inflammation in atopic dermatitis

Dry skin, pain, and itching... Atopic dermatitis affects the everyday lives of nearly 20% of children, and up to 5% of adults. The condition can have a significant impact on the quality of life of these patients.

7 Oct 2019

New defensive mechanism against bacterial wound infections discovered

Wound inflammation which results in impaired wound healing can have serious consequences for patients. Researchers from Charité - Universitätsmedizin Berlin have discovered a new defensive mechanism which enables our skin to actively kill bacteria.

4 Oct 2019

Newly synthesized anticancer compound can block cancer signaling mechanism

Of the various different functions that proteins perform in a cell, a crucial one is the recognition and transmission of certain "signals," collectively referred to as signal transduction.

24 Sep 2019

Authenticated mast cells successfully developed from hematopoietic stem cells

Mast cells are critically involved in immunity and immune disorders. However, they are rarely cultured ex vivo for experimental manipulation because of the difficulty in isolating useful numbers and limitations related to 2D culture.

20 Sep 2019

A novel approach to intraplaque mast cell characterization in atherosclerosis

Researchers have devised a new flow-cytometric method to identify a subpopulation of intraplaque mast cells, the primary immune mediators of atherosclerosis.

6 Jun 2019

Newly identified skin-gut communication helps illuminate link between food allergy and eczema

Scratching the skin triggers a series of immune responses culminating in an increased number of activated mast cells--immune cells involved in allergic reactions--in the small intestine, according to research conducted in mice.

24 Apr 2019

Researchers map genetic mutation behind incurable disease

Researchers at Karolinska Institutet have mapped the genetic mutation behind the incurable disease systemic mastocytosis.

10 Apr 2019

Allergic reactions trigger changes in brain behavior development in unborn males and females

Researchers at the University of Maryland School of Medicine and colleagues at Ohio State University have discovered that allergic reactions trigger changes in brain behavior development in unborn males and females.

29 Mar 2019

New research aims to find how asthma symptoms are aggravated

America's 26 million asthmatics may be able to breathe a sigh of relief, thanks to Dr. Sailaja Paruchuri, a University of Akron researcher who has received a $1.9 million Research Project Grant from the National Institutes of Health-National Institute of Allergy and Infectious Diseases.

19 Mar 2019

Interaction between two immune cells may play key role in fight against dengue virus

Researchers at Duke-NUS Medical School have demonstrated for the first time a physical interaction between two types of immune cells that plays an important role in the early fight against dengue virus infection.

8 Feb 2019

Research may pave way for development of potent weapons against cancer

Despite significant advances in cancer research, the disease continues to exact a devastating toll. Because cancer is a disease of the body's own cells, which mutate and develop under evolutionary pressure, conventional treatments like chemotherapy and radiation often leave behind a residue of resistant cells that go on to expand and wreak havoc.

27 Nov 2018

Mast cells associated with allergies also play key role in survival, study reveals

In a University of California, Irvine-led study, researchers found evidence that mast cells, an important group of immune cells typically associated with allergies, actually enable the body to survive fasting or intense exercise.

12 Oct 2018

Two major studies on canine cancers may provide clues on human cancers

Two studies into deadly cancers in dogs are now underway, offered through the newly formed Clinical Trials Office at Cummings Veterinary Medical Center at Tufts University. Dogs with spontaneous osteosarcoma, as well as dogs with mast cell tumors and solid tumors, may be eligible for enrollment.

12 Oct 2018

Mast Cell News and Research

Researchers study how allergens get on our nerves to drive inflammation in atopic dermatitis

New defensive mechanism against bacterial wound infections discovered

Newly synthesized anticancer compound can block cancer signaling mechanism

Authenticated mast cells successfully developed from hematopoietic stem cells

A novel approach to intraplaque mast cell characterization in atherosclerosis

Newly identified skin-gut communication helps illuminate link between food allergy and eczema

Researchers map genetic mutation behind incurable disease

Allergic reactions trigger changes in brain behavior development in unborn males and females

New research aims to find how asthma symptoms are aggravated

Interaction between two immune cells may play key role in fight against dengue virus

Research may pave way for development of potent weapons against cancer

Mast cells associated with allergies also play key role in survival, study reveals

Two major studies on canine cancers may provide clues on human cancers

Study reveals how immune cells in the brain influence sexual behavior

Study unravels novel cellular and molecular pathway that regulates innate, adaptive immunity

Researcher provides insight into how stress causes physical symptoms and disease

Study: People with rare diseases at high risk for experiencing poor quality of life

Study identifies new role for stress receptor CRF1 expressed on mast cells

Inexplicable cases of anaphylaxis caused by uncommon red meat allergy, study finds

Study provides new insight into development of immune cells

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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