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Hydroxychloroquine fails to modify HIV in patients not taking ART

The use of hydroxychloroquine does not reduce CD8 cell activation in HIV-infected patients not taking antiretroviral therapy, research shows.

30 Jul 2012

Conception plans miscarry with sperm DNA damage

Sperm with damaged DNA are more likely to cause spontaneous pregnancy loss, report researchers.

30 Jul 2012

Strategies to reduce readmission are lacking in US hospitals

A review of US hospitals indicates a lack of implementation of important practices to reduce readmission rates among patients with heart failure and acute myocardial infarction, report researchers.

30 Jul 2012

Walking speed could explain high BP and mortality link in elderly

Elderly individuals with high systolic blood pressure who walk quickly have a higher mortality rate than their counterparts who walk more slowly, show US study results.

30 Jul 2012

Erosive hand osteoarthritis ‘a distinct phenotype’

There may be an underlying systemic cause for erosive hand osteoarthritis, suggest study findings showing more inflammatory signs in erosive joints relative to non-erosive joints.

30 Jul 2012

Vitamin D link to lung function in smokers

Vitamin D levels seem to determine the rate of lung function decline among smokers, the results of an American study show.

27 Jul 2012

Steak and ticks: A potentially life-threatening experience

Tick bites can trigger a severe, delayed allergic reaction to red meat, suggest findings published in the Journal of General Internal Medicine.

27 Jul 2012

Increased risk for AMI following hip- and knee-replacement surgery

Elderly patients are at a significantly increased risk for acute myocardial infarction in the 2 weeks following total hip- or knee-replacement surgery, research shows.

27 Jul 2012

Sirolimus has anti-skin cancer effect in kidney transplant patients

Switching from calcineurin inhibitors to a sirolimus-containing immunosuppression regimen may help reduce the incidence of secondary skin cancer after kidney transplantation, suggests research published in TheNew England Journal of Medicine.

27 Jul 2012

Oximetry detects sleep disorder in stroke patients

Nocturnal oximetry is an accurate instrument for detecting and diagnosing sleep apnea syndrome in patients with stroke, research indicates.

27 Jul 2012

Long-term use of reverse geometry lenses may induce inflammatory response

Continuous long-term overnight use of reverse geometry lenses results in a significantly increased presence of inflammatory mediators compared with wearing 30-night silicone-hydrogel contact lenses or wearing no lenses, show study results.

27 Jul 2012

Discrepancies in ICU use identified

An analysis of intensive care unit use in the USA reveals that many patients admitted to this specialist department are at low risk for mortality, while more than half of patients with a high mortality risk are admitted to other departments.

27 Jul 2012

Long-term linagliptin effective treatment for Type 2 diabetes

Linagliptin is an effective and well-tolerated therapy for the long-term management of Type 2 diabetes, say the authors of an open-label extension study published in the International Journal of Clinical Practice.

27 Jul 2012

Anticancer benefit to giving birth after 30

Women who last give birth after the age of 30 years have a decreased risk for endometrial cancer, researchers report in the American Journal of Epidemiology.

27 Jul 2012

Diabetes cutoffs don’t quite cut it for South Asians

Individuals of South Asian origin may require closer monitoring for Type 2 diabetes, suggest researchers.

27 Jul 2012

‘Narrow therapeutic window’ for oxygen in brain injury

Hyperoxia, as well as hypoxia, early after hospital admission is associated with poor outcomes and mortality in patients with traumatic brain injury, report researchers in the Archives of Surgery.

27 Jul 2012

Further evidence for dermatologic benefits of propanolol

Results from a Greek study give further support to the use of propanolol as a first-line treatment for problematic infantile hemangiomas.

26 Jul 2012

Study supports sphincter-saving surgery

Fissurectomy results in high levels of healing and low rates of anal incontinence, show the results of the largest ever prospective study of the technique.

26 Jul 2012

Surgical distractions could have disastrous consequences

In a simulated study, the rate of major errors committed while novice surgeons were exposed to typical interruptions and distractions was almost 50%, indicating that such exposure could seriously risk patient safety.

26 Jul 2012

Vitamin A insufficiency linked to hand, foot and mouth disease

Vitamin A status is associated with immunity to, and pathogenic condition of, hand, foot, and mouth disease in children, say researchers whose study results show that the majority of those with the infectious disease also had vitamin A insufficiency.

26 Jul 2012