Medicinal Chemistry News and Research

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Opentrons Flex™ Lab Robot Launches to Accelerate Bioautomation Across Thousands of Life Science Experiments

Opentrons, a leader in lab automation, announces the launch of its Opentrons Flex robot, a new generation of affordable and easy-to-program liquid-handling lab robots designed to level the playing field for labs of all sizes and bring advanced lab automation to more researchers than ever before.

From Opentrons 22 May 2023

H.E.L Group makes senior appointments as it continues to scale globally

Hasan Hallaq, PhD appointed as European Sales Director, Victoria Ordsmith joins as Director of Marketing and Sarennah Longworth-Cook promoted Director of People.

From H.E.L Group 16 May 2023

Structure of protein methyltransferase from the monkeypox virus deciphered

Scientists from the Institute of Organic Chemistry and Biochemistry in Prague have deciphered the structure of the protein methyltransferase from the monkeypox virus

30 Apr 2023

Optibrium appoints computational modelling expert, Dr Hamed Tabatabaei Ghomi as Head of Research

Optibrium, a leading developer of software and AI solutions for drug discovery, today announced the appointment of Dr Hamed Tabatabaei Ghomi as Head of Research.

From Optibrium Ltd. 4 Apr 2023

New way to safely, sustainably synthesize a molecule with remarkable anticancer properties

Plants produce all types of curious chemicals. Some deter predators. Some smell wonderful. Some even have medicinal value.

23 Mar 2023

Bitter taste receptors are a potential target for treating asthma or COPD

Surprisingly, bitter taste receptors are not only located in the mouth, but also elsewhere in the body, including the airways.

13 Mar 2023

St. Jude researchers show how drug makers can avoid toxicity and resistance

Scientists at St. Jude Children's Research Hospital have demonstrated how drug makers can avoid two key problems: toxicity and resistance.

28 Feb 2023

Rapid AAV Titer for Bioprocessing in Gene Therapy

In this article, News-Medical talks to Sartorius about biosensing and bioprocessing in gene therapy, while also discussing the various products Sartorius produces in order to aid in this.

From Sartorius 27 Feb 2023

Protein degradation approach can be used to hit an ‘undruggable’ target against cancer

The protein STAT5 has long been an appealing target against cancer, but after decades of research it was consigned to the "undruggable" category.

15 Feb 2023

Oncodesign Services looks to the future

As Oncodesign evolves into Oncodesign Services and begins its journey as an independent business, CEO Fabrice Viviani explains his hopes and plans for the company’s future.

From Oncodesign Services 3 Feb 2023

New candidate molecule could become an effective non-hormonal male contraceptive

Despite birth control existing for decades, almost none of the options specifically target sperm cells. Researchers are now developing approaches that target testosterone or otherwise interrupt the sperm's ability to fertilize an egg, yet these may not work for everyone.

30 Jan 2023

Understanding the mechanisms involved in heart disease and cancers

In a crucial step towards understanding the mechanisms involved in cardiovascular disease and certain cancers, a Canadian led research team has succeeded in a world first: they've found the molecular mechanism by which the protein PCSK9 degrades the receptor of low density lipoproteins, the richest cholesterol particles in the bloodstream.

19 Jan 2023

Mucosal DNA vaccine provides protection against lethal SARS-CoV-2 in mice

Less known to the general public, mucosal vaccination via the mucus membranes could provide robust protection against SARS-CoV-2 infections.

16 Dec 2022

Researchers design novel compounds with potential as drug treatments for COVID-19

The ongoing COVID-19 pandemic, caused by the SARS-CoV-2 virus, has been devastating the entire world. While the vaccination program is advancing, drug treatments for COVID-19 are still highly important for those who become infected.

9 Dec 2022

Metrion Biosciences invests in new High Throughput Screening capability and expanded facilities

Metrion Biosciences Limited (“Metrion”), the specialist ion channel contract research and drug discovery company, today announced the launch of its High Throughput Screening (HTS) capability, as well as the expansion of its state-of-the-art lab and office facilities. Scott Maidment has been appointed as Head of HTS to lead the new service.

From Metrion Biosciences Limited 1 Dec 2022

New chemical probe can selectively inhibit human COQ8A protein in cells

Inhibition of the COQ8 protein could be beneficial in the treatment of diseases such as cancer. COQ8 is needed for the biosynthesis of coenzyme Q, also known as ubiquinone.

28 Nov 2022

Cancer Research Horizons, Newcastle University extend strategic drug discovery alliance with Astex Pharmaceuticals

Cancer Research UK’s newly launched innovation engine, Cancer Research Horizons, and Newcastle University, have announced a further significant extension of their strategic drug discovery alliance with Astex Pharmaceuticals (UK) (‘Astex’), a biotechnology company dedicated to the discovery and development of novel small molecule therapeutics.

22 Nov 2022

Collaboration aims to develop new medicines for neurodegenerative diseases

The ALBORADA Drug Discovery Institute (ADDI) today (Tuesday 8 November) announced that it will collaborate with pharmaceutical company YD Global Life Science (YDGLS) to develop inhibitors of the unfolded protein response for the treatment of the diseases that cause dementia.

9 Nov 2022

Researchers develop special molecules that stimulate the immune system

Surgery, radiation, and chemotherapy are the three main therapies used to treat cancerous tumors. The doctoral research network 'Magicbullet::Reloaded'is investigating another approach, with 15 doctoral researchers developing special molecules that stimulate the immune system to destroy tumor cells. In a video, network members explain how doctoral researchers gain valuable experience and research opportunities as part of the network.

1 Nov 2022

Two small molecules reverse pancreatic acinar ductal metaplasia

Pancreatic cancer often lurks as a silent disease. With no known symptoms, it can progress undetected and spread to other organs.

20 Oct 2022