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Indian government rejects Abbott's patent application for second-line ARV

India's patent office "has rejected American drug maker Abbott Laboratories' patent application for an HIV combination drug, allowing low-cost local drug makers to make and sell their generic versions in India and other countries where the medicine is not patented," Economic Times reports (1/4).

5 Jan 2011

Critical tuning dial for controlling whole body energy

Researchers have found what appears to be a critical tuning dial for controlling whole body energy, according to a new report in the January issue of Cell Metabolism, a Cell Press publication. When energy levels within cells drop, it sets off a series of events designed to increase the amount of calorie-rich dietary fat that the body will absorb.

5 Jan 2011

New mouse model with deficiency of lipoprotein lipase in neurons

Researchers at the University of Colorado School of Medicine have created a new and exciting mouse model to study how lipid sensing and metabolism in the brain relate to the regulation of energy balance and body weight. The research team, led by Hong Wang, PhD, created mice with a deficiency of lipoprotein lipase (LPL) in neurons, and observed two important reactions.

5 Jan 2011

Blocking activation of delta-PKC enzyme could protect lungs from neutrophil-mediated damage

All of us may be able to breathe a little easier now that scientists from Pennsylvania have found a new therapeutic target for controlling dangerous inflammation in the lungs. A new research report in the January 2011 issue of the Journal of Leukocyte Biology (http://www.jleukbio.org) suggests that blocking the activation of an enzyme called delta-protein kinase C (delta-PKC) could protect the lungs from neutrophil-mediated damage, which can result in out of control inflammation.

5 Jan 2011

NTU announces $150 million Lee Foundation gift for new medical school

Nanyang Technological University today announced a gift of $150 million by the Lee Foundation towards the new medical school with half of the sum going directly to needy students. Together with the enhanced Singapore Government matching, NTU will receive a gift amounting to $400 million.

5 Jan 2011

Dongsheng obtains exclusive sales rights of Thymosin Alpha 1 Injection in China

Dongsheng Pharmaceutical International Co., Ltd. announced today that it has obtained the exclusive sales rights of Thymosin Alpha 1 Injection in 19 provinces in China from Shanghai Biochemistry Pharmaceutical Co. I.

5 Jan 2011

High risk of burnout among residents and senior physicians

The January issue of the journal Anesthesiology examines the issue of burnout among anesthesiologists. Two studies provide significant burnout statistics among these highly trained medical specialists, and editorials offer personal perspective on the issue as well as advice on how best to avoid professional burnout.

5 Jan 2011

Removal of ZIP proteins from hippocampus cell protects them from injury

Researchers in the Blue Bird Circle Developmental Neurogenetics Laboratory in the department of neurology at Baylor College of Medicine have discovered that zinc enters cells through specialized protein gates known as ZIP transporters, and removing these ZIP proteins from cells in the hippocampus significantly protects them from injury.

5 Jan 2011

Metabolic cost of missing one night of sleep equivalent to walking two miles

In the first-ever quantification of energy expended by humans during sleep, a University of Colorado team has found that the metabolic cost of an adult missing one night of sleep is the equivalent of walking slightly less than two miles.

5 Jan 2011

Two doses of varicella vaccine provide higher antibody levels than one

When vaccinating children against varicella, researchers at Yale School of Medicine have found, two doses are better than one. In fact, the odds of developing chicken pox were 95 percent lower in children who had received two doses of the vaccine compared with those who had received only one dose.

5 Jan 2011

Researchers develop unique vaccine that produces long-lasting anti-cocaine immunity in mice

Researchers from The Scripps Research Institute, Weill Cornell Medical College, and Cornell University have produced a long-lasting anti-cocaine immunity in mice by giving them a unique vaccine that combines bits of the common cold virus with a particle that mimics cocaine.

5 Jan 2011

Study suggests new experimental drug is better than standard morphine

A little-known morphinelike drug is potentially more potent, longer lasting and less likely to cause constipation than standard morphine, a study led by a Loyola University Health System anesthesiologist has found.

5 Jan 2011

Santaris Pharma, Pfizer expand RNA-targeted medicine collaboration

Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the research and development of mRNA and microRNA targeted therapies, and Pfizer Inc., today announced that the companies have expanded their collaboration directed to the development and commercialization of RNA-targeted medicines using Santaris Pharma A/S Locked Nucleic Acid (LNA) Drug Platform.

5 Jan 2011

Grubb & Ellis Healthcare announces acquisition of Lawton Medical Office Building Portfolio

Grubb & Ellis Healthcare REIT II, Inc. today announced that it has acquired Lawton Medical Office Building Portfolio, a two-property medical office building portfolio on the campus of Southwestern Medical Center in Lawton, Okla., and Ennis Medical Office Building, a 30,000-square-foot medical office building in Ennis, Texas.

5 Jan 2011

Study: Stem cells play an unexpected role in male pattern balding

Given the amount of angst over male pattern balding, surprisingly little is known about its cause at the cellular level. In a new study, published in the Journal of Clinical Investigation, a team led by George Cotsarelis, MD, chair of the Department of Dermatology at the University of Pennsylvania School of Medicine, has found that stem cells play an unexpected role in explaining what happens in bald scalp.

5 Jan 2011

Increased amounts of MMP-1 enzyme may explain preeclampsia symptoms in pregnant women

Virginia Commonwealth University School of Medicine researchers have found that a significant increase of an enzyme in the blood vessels of pregnant women with preeclampsia may explain some of the symptoms associated with the condition, including hypertension, swelling and protein in the urine.

5 Jan 2011

Dutch scientists provide new insights into intestinal cancer through plant study

Dutch scientists have gained important new insights into intestinal cancer from studying a plant. The disease is called Peutz-Jeghers Syndrome, a hereditary disorder where people develop intestinal polyps that turn into malignant tumors.

5 Jan 2011

Opinions: U.S. International Affairs Budget; Health impacts of climate change; Role of U.N.; Drug development, free trade

Despite challenging economic times, "[t]wo areas we cannot afford to shortchange right now ... are our national security and our economic prosperity, which is why we must continue to have a strong and effective International Affairs Budget," U.S. Global Leadership Coalition Communications Director Richard Parker writes in a FoxNews.com opinion piece.

5 Jan 2011

Today's Opinions: GOP rerun; Finding bipartisanship; Pawlenty's legacy

You just can't close the door on this crowd. The party that brought us the worst economy since the Great Depression, that led us into Iraq and the worst foreign policy disaster in American history, that would like to take a hammer to Social Security and a chisel to Medicare, is back in control of the House of Representatives with the expressed mission of undermining all things Obama (Bob Herbert, 1/3).

4 Jan 2011

Vaccine blocks cocaine high in mice - human trials likely

Researchers have produced a lasting anti-cocaine immunity in mice by giving them a safe vaccine that combines bits of the common cold virus with a particle that mimics cocaine.

4 Jan 2011