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Role for microRNAs in limb regeneration

In the March 15th issue of G&D, Dr. Kenneth Poss (Duke University Medical Center) and colleagues reveal that microRNA depletion is a necessary step in tissue regeneration - a discovery with interesting implications for their use in regenerative medicine.

17 Mar 2008

Near-infrared light used to detect signs of Alzheimer's disease

A team of researchers in Bedford, Mass. has developed a way of examining brain tissue with near-infrared light to detect signs of Alzheimer's disease.

17 Mar 2008

Researchers study new drug and indications for heated chemotherapy treatment

Studies have shown that surgery combined with Intraperitoneal Hyperthermic Chemotherapy (IPHC) can improve survival rates for select patients with peritoneal carcinoma (cancer of the lining of the abdominal cavity) that has spread from colorectal or appendix cancer.

17 Mar 2008

Penn researchers identify first sex chromosome gene involved in meiosis and male infertility

A team of scientists led by University of Pennsylvania veterinary researchers have identified a gene, TEX11, located on the X chromosome, which when disrupted in mice renders the males sterile and reduces female fecundity.

17 Mar 2008

Pain-free and drug-free labour? Get real!

A pain-free and drug-free labour may be many expectant mothers' dream but a review in the open access journal BMC Medicine reveals that reality hits hard.

17 Mar 2008

Advair reduces asthma-related hospitalization and emergency department visits

Advair Diskus (fluticasone propionate and salmeterol inhalation powder) was associated with fewer asthma-related hospitalizations and emergency department (ED) visits in pediatric patients when compared to the use of inhaled corticosteroids (ICS) alone, and use of Advair by pediatric and adult patients through the summer was associated with fewer hospitalizations and ED visits in the fall.

17 Mar 2008

Minority, low-income diabetics least likely to monitor their blood glucose

Black and Hispanic adults with insulin-treated diabetes are less likely than whites to monitor their blood glucose, according to a new study presented at the American Heart Association's 48th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.

17 Mar 2008

Transcendental meditation controls high blood pressure

Transcendental Meditation is an effective treatment for controlling high blood pressure with the added benefit of bypassing possible side effects and hazards of anti-hypertension drugs, according to a new meta-analysis conducted at the University of Kentucky.

17 Mar 2008

Researchers at Mayo Clinic say ECG standards should be revised for elderly

Researchers at Mayo Clinic suggest that the established "normal" ranges for evaluating electrocardiograms for persons over 80 years old should be "revisited."

17 Mar 2008

Investigational drug Debio-025 tested for preventing muscle fiber death in muscular dystrophy

An investigational antiviral drug currently undergoing human trials in Europe for treating Hepatitis C infections may have potential to reduce muscle cell damage in Duchenne and other forms of muscular dystrophy (MD).

17 Mar 2008

Indiana University -Kenya Partnership to be honored by the International Center of Indianapolis

The Indiana University-Kenya Partnership will be honored by the International Center of Indianapolis as the recipient of its annual International Citizen of the Year Award to be presented in September.

17 Mar 2008

Human Proteinpedia, a portal to share human protein data among the scientific community

Today, scientists have access to a large amount of biological information through the Internet.

17 Mar 2008

Breast cancer more aggressive among overweight or obese women

Women with breast cancer have more aggressive disease and lower survival rates if they are overweight or obese, according to findings published in the March 15 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.

17 Mar 2008

Blood vessel protein reverses macular degeneration, diabetic retinopathy in mice

Two major eye diseases and leading causes of blindness—age-related macular degeneration and diabetic retinopathy can be reversed or even prevented by drugs that activate a protein found in blood vessel cells, researchers at the University of Utah School of Medicine and several other institutions have announced in a new study.

17 Mar 2008

Toddlers affected most by secondhand smoke exposure at home

Secondhand smoke in the home appears to induce markers for heart disease as early as the toddler years, researchers reported at the American Heart Association's 48th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.

14 Mar 2008

Next emerging disease will come from tropics, say scientists

Scientists from four well-known institutions say the next major disease like HIV/AIDS or SARS could occur in any of a number of developing countries concentrated along the equator.

14 Mar 2008

Finding in mice could help prevent common complications of kidney damage

Kidney damage often sets off a slew of complications in patients, spreading organ failure like wildfire throughout their bodies.

14 Mar 2008

Cancer drug allergies

Cancer patients from the Southeastern United States who are treated with the drug cetuximab, known commercially as Erbitux, are far more likely to suffer severe allergic reactions than patients in other regions of the country.

14 Mar 2008

Simple laboratory test predicts risk of kidney injury after surgery

A simple laboratory test may provide a new way for doctors to identify patients at risk of developing potentially severe acute kidney injury (AKI) after surgery up to three days before the problem would otherwise be detected, reports a pilot study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology .

14 Mar 2008

Low cost tactics improve medication use after heart attack

Direct-to-patient communication about the importance of continuing prescription drug treatment after a heart attack is a simple, low-cost way to increase the likelihood of patients adhering to life saving therapies at least four out of every five days.

14 Mar 2008