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Fructose overload

Here's one tip for how to eat at the holidays: Don't take your cues from Santa. The sugary cookies and fat-laden fruitcakes the mythical North Pole resident eats are a no-no.

13 Dec 2007

Blood transfusions linked to surgery complications in women

Women die and get infections more often than men after heart surgery because they tend to receive more blood transfusions, which boost the risks of bad outcomes, according to a study published in the December Journal of Women's Health.

13 Dec 2007

DAB2IP gene linked to aggressive prostate cancer

Results from two genome-wide association studies have identified a genetic variant of the DAB2IP gene that is associated with the risk of aggressive prostate cancer.

13 Dec 2007

Great-grandparent of all the cells of the blood identified

Researchers at the Stanford University School of Medicine have isolated a human blood cell that represents the great-grandparent of all the cells of the blood, a finding that could lead to new treatments for blood cancers and other blood diseases.

13 Dec 2007

Setting a course for the future of tissue engineering

The editors of Tissue Engineering asked 24 leaders in the field what critical steps are needed for tissue engineering to achieve broad critical success by the year 2021 and published their findings in the December 2007 issue (Volume 13, Number 12).

13 Dec 2007

Sedative may have better outcomes than common medication for ICU patients on respirator

Intensive care unit patients on respirators who were sedated with the drug dexmedetomidine had more days alive without delirium or coma and better sedation compared to patients treated with the recommended drug lorazepam, according to a study in the December 12 issue of JAMA.

13 Dec 2007

New ray of hope for children with Batten disease

Investigators at the University of Rochester Medical Center have uncovered a promising drug therapy that offers a ray of hope for children with Batten disease

13 Dec 2007

PET/CT imaging proves golden for detecting cancer in children

PET/CT imaging exhibits significantly higher sensitivity, specificity and accuracy than conventional imaging when it comes to detecting malignant tumors in children, according to research published in the December issue of the Journal of Nuclear Medicine.

13 Dec 2007

Likelihood of falling pregnant steadily decreases the fatter a woman is

A new study of obesity and the probability of pregnancy has shown that a woman's chances of a spontaneous pregnancy steadily decrease the fatter she is.

13 Dec 2007

Time to remove the stigma associated with incontinence

An independent panel convened this week by the NIH found that fewer than half of individuals experiencing fecal or urinary incontinence - the inability to control bowel movements or urination, respectively - report their symptoms to healthcare providers without being prompted.

13 Dec 2007

New quicker technique for sequencing DNA

Using computer simulations, researchers at the University of Illinois have demonstrated a strategy for sequencing DNA by driving the molecule back and forth through a nanopore capacitor in a semiconductor chip.

13 Dec 2007

Novel way to diagnose mantle cell lymphomas

Mantle cell lymphoma is an aggressive form of blood cancer that most commonly afflicts older men.

13 Dec 2007

More regulatory DNA than previously thought

Surrounding the small islands of genes within the human genome is a vast sea of mysterious DNA. While most of this non-coding DNA is junk, some of it is used to help genes turn on and off.

13 Dec 2007

Discovery of key mechanism underlying idiopathic pulmonary fibrosis

A study led by Massachusetts General Hospital (MGH) researchers may have found a key mechanism underlying idiopathic pulmonary fibrosis (IPF), a usually fatal lung disease for which transplantation is the only successful treatment.

13 Dec 2007

Researchers advance stem cell gene therapy

Ireland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with less severe side effects.

13 Dec 2007

Intensive care quality of sleep improved by new drug dexmedetomidine

A new sedative drug has been shown to improve the sleep quality and comfort levels of intensive care patients, compared to the most commonly-used medication, according to research published today in the journal JAMA.

13 Dec 2007

Immune compound blocks virus' ability to hijack antibodies

Researchers at Washington University School of Medicine in St. Louis have shown that a controversial phenomenon known as antibody-dependent enhancement (ADE) of infection is suppressed by C1q, a blood-borne immune system compound.

13 Dec 2007

GlaxoSmithKline response to JAMA article on ICES retrospective analysis

The following is GlaxoSmithKline's response to the retrospective analysis by the Institute for Clinical Evaluative Sciences (ICES) titled "Thiazolidinediones and Cardiovascular Outcomes in Older Patients with Diabetes".

13 Dec 2007

Geriatric care intervention appears to provide some benefits for low-income seniors

A home-based geriatric care program for low-income seniors resulted in higher-quality medical care, improvement in quality of life and fewer emergency department visits, but did not appear to prevent decline in physical functioning, according to a study in the December 12 issue of JAMA: The Journal of the American Medical Association.

13 Dec 2007

Variant of a tumor suppressor gene associated with aggressive prostate cancer

A variant of a tumor suppressor gene may be associated with an increased risk of aggressive prostate cancer, according to a study published online December 11 in the Journal of the National Cancer Institute.

13 Dec 2007