Melanoma

Melanoma is a form of cancer that begins in melanocytes (cells that make the pigment melanin). It may begin in a mole (skin melanoma), but can also begin in other pigmented tissues, such as in the eye or in the intestines.

What are Melanomas?

The treatment of melanoma may involve surgery, immunotherapy, targeted therapy, chemotherapy or radiotherapy, or a combination of several treatment techniques. Each of these treatments is outlined below.

Melanoma Symptoms and Cause

How is Melanoma Diagnosed and Treated?

Melanoma Prognosis

Melanoma History

Melanoma Research

Choroidal Melanoma

Managing Choroidal Melanomas

Malignant Melanoma

Metastatic Melanoma

What are the Statistics of Melanoma?

Latest Melanoma News and Research

Genetically engineering skin bacteria to fight cancer

While studying a type of bacteria that lives on the healthy skin of every human being, researchers from Stanford Medicine and a colleague may have stumbled on a powerful new way to fight cancer.

15 Apr 2024

Breakthrough study reveals melanoma's resistance tactics to targeted therapy

Melanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to alleviate the health burden of the disease. Important advances in recent years include doctors using genetic tests to look for specific mutations they can target for more personalised, effective treatment.

13 Apr 2024

New murine model sheds light on anti-MDA5 antibody-positive dermatomyositis

Some diseases involve autoimmune reactions, when the body begins to attack its own cells and proteins.

13 Apr 2024

NCCN 2024 Annual Conference focuses on practical applications for improving cancer care

The National Comprehensive Cancer Network (NCCN)-;an alliance of leading cancer centers-;hosted more than 1,700 oncology professionals during the NCCN 2024 Annual Conference on April 5-7.

13 Apr 2024

Tumor microbiomes offer new insights for enhancing cancer therapies

Comprehensive review reveals the significant impact of tumor-resident bacteria on metastatic cancer, showing how microbiome genomes influence tumor biology, immune system response, and treatment effectiveness. It lays the groundwork for utilizing bacteria-focused therapies to complement traditional cancer treatments.

11 Apr 2024

Childhood obesity not linked to adult skin cancer risk, study says

Study leverages a Mendelian randomization approach to explore if childhood obesity genetically predisposes individuals to adult skin cancer, finding no significant correlation.

7 Apr 2024

Does IBD affect cancer risk?

Research suggests no strong genetic link between inflammatory bowel disease and increased cancer risk, with specific exceptions in European populations for Crohn's disease and ulcerative colitis.

3 Apr 2024

Advances and hurdles: The impact of AI on oncology care efficiency and mortality rates

The benefits and limitations of precision medicine techniques in oncology research and treatment.

3 Apr 2024

Second-generation melanoma vaccine prolongs survival of patients with skin cancer

A second-generation melanoma vaccine being developed at UVA Cancer Center improves long-term survival for melanoma patients compared with the first-generation vaccine, new research shows.

29 Mar 2024

Research from NY highlights pollution as a key factor in rising cancer rates among youth

Cancer incidence trends among adults in the New York State (NYS) and associations with common population-level exposures.

28 Mar 2024

As AI eye exams prove their worth, lessons for future tech emerge

Christian Espinoza, director of a Southern California drug-treatment provider, recently began employing a powerful new assistant: an artificial intelligence algorithm that can perform eye exams with pictures taken by a retinal camera. It makes quick diagnoses, without a doctor present.

27 Mar 2024

Aging affects regulatory T cells' ability to promote myelin regeneration

Regulatory T lymphocytes are cells that are responsible for regulating the immune system and have regenerative functions in many contexts, including myelin restoration.

20 Mar 2024

AI-based mobile app can diagnose melanoma with very high precision

A mobile app that uses artificial intelligence, AI, to analyze images of suspected skin lesions can diagnose melanoma with very high precision.

20 Mar 2024

Machine learning classifier reduces the time to identify personalized tumor reactive T cell receptors

Making a personalized T cell therapy for cancer patients currently takes at least six months; scientists at the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.

15 Mar 2024

DNA origami vaccine DoriVac paves way for personalized cancer immunotherapy

Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading.

15 Mar 2024

New analysis sheds light on cancer incidence and mortality trends in the UK

Trends in cancer incidence and deaths in the United Kingdom (UK) among individuals aged between 35 and 69 years.

14 Mar 2024

Study reveals decline in cancer mortality among middle-aged people in the UK

A study by Cancer Research UK has revealed that fewer middle-aged people are dying from cancer in the UK than at any point over the last 25 years.

13 Mar 2024

Increased stiffness in aging skin may contribute to higher rates of metastatic skin cancer

Age-related changes that cause the skin to stiffen and become less elastic may also contribute to higher rates of metastatic skin cancer in older people, according to research by investigators from the Johns Hopkins Kimmel Cancer Center.

12 Mar 2024

LAG-3 protein structure may be the key to unlocking new cancer treatments

A molecular “snapshot” of a protein can be critical to understanding its function. Scientists at Stanford and NYU have published and investigated a new structure of the protein LAG-3 which could enable the development of new cancer treatments.

11 Mar 2024

UCLA and UAMS teams secure $3.2 million NIH grant for melanoma research

A team of investigators from the UCLA Health Jonsson Comprehensive Cancer and the University of Arkansas for Medical Sciences (UAMS) Winthrop P. Rockefeller Cancer Institute was awarded a $3.2 million grant from the National Institutes of Health to identify new ways to prevent and overcome treatment resistance to targeted therapy in patients with all sub-types of cutaneous melanoma, an aggressive form of skin cancer.

11 Mar 2024