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The roles and plausible mechanisms of pyroptosis in renal inflammation and fibrosis

Researchers summarize available data on pyroptosis in the context of renal fibrosis, as well as its prevention and treatment.

1 Aug 2023

SARS-CoV-2 spike pseudovirion infection in ARPE-19 cells is a dynamin-dependent process that is primarily mediated by LDLR

Researchers reported on lentiviral pseudovirions pseudotyped with SARS-CoV-2.

1 Aug 2023

Newly identified protein plays a key role in the action of emerging anticancer therapies

Scientists have identified a protein that plays a pivotal role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to fine-tune the use of immunotherapies against several challenging cancers.

31 Jul 2023

The essential role of the MPL36 protein in leptospirosis

The Leptospira membrane protein L36 (MPL36) is essential for its pathogenesis.

31 Jul 2023

The impact of diabetes mellitus on morbidity and mortality in patients with COVID-19

Researchers examine the impact of DM on post-COVID-19 clinical outcomes.

31 Jul 2023

New method allows the discovery of specific inhibitors of lactate transporter

Scientists from the Giulio Superti-Furga Lab at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, have developed a new method that allows the discovery of specific inhibitors of a lactate transporter associated with cancer and other disease areas.

28 Jul 2023

New technology could revolutionize treatment for age-related macular degeneration

Scientists have found a way to use nanotechnology to create a 3D 'scaffold' to grow cells from the retina –paving the way for potential new ways of treating a common cause of blindness.

28 Jul 2023

COVID-19 treatment: study evaluates ACEi and ARB effects on clinical outcomes

A group of researchers compared the effects of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers.

27 Jul 2023

Researchers make breakthrough in fight against mucosal melanoma

Although rare, mucosal melanoma in humans has a low survival rate. It has been difficult to investigate due to a lack of similar cancers in animals for study.

26 Jul 2023

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

The study described in Scientific Reports highlights an impaired response to the hormone progesterone (P4) in cervical fibroblasts from patients with refractory cervical insufficiency (CI).

26 Jul 2023

Anti-inflammatory nanoparticles show promise in treating inflammatory bowel disease

Chronic inflammatory bowel disease (IBD), such as Crohn’s disease and ulcerative colitis, is on the rise worldwide. The benefits of current medications are limited by problematic side effects.

24 Jul 2023

New sensor may be deployed to screen patients for hard-to-diagnose cancers

Drawing inspiration from natural sensory systems, an MIT-led team has designed a novel sensor that could detect the same molecules that naturally occurring cell receptors can identify.

21 Jul 2023

Advancing vaccine adjuvants: exploring cutting-edge platforms for improved immunization

A group of authors summarized adjuvant mechanisms, characteristics, and applications, seeking to overcome current vaccine limitations.

21 Jul 2023

Trypsin and anaerobic bacteria boost SARS-CoV-2 Delta variant infectivity: oral hygiene key to prevention

Researchers investigated whether trypsin, a protease, increased SARS-CoV-2 infectivity.

21 Jul 2023

Researchers discover new way to target bacterial cell wall

The bacterial cell wall must be constantly remodeled in order to grow and divide. This involves the close coordination of lytic enzymes and peptidoglycan synthesis.

20 Jul 2023

High body temperature may boost gut microbiota to fight viral infections

Researchers from The University of Tokyo unravel the connection between high body temperature and increased viral resistance.

20 Jul 2023

Study examines the antibacterial properties of cinnamon and eucalyptus essential oils compared with their isolated major compounds

A comparison of the antibacterial properties of Cinnamonum cassia and Eucalyptus globulus to their most abundant bioactives metabolites.

20 Jul 2023

Membrane News and Research

The roles and plausible mechanisms of pyroptosis in renal inflammation and fibrosis

SARS-CoV-2 spike pseudovirion infection in ARPE-19 cells is a dynamin-dependent process that is primarily mediated by LDLR

Newly identified protein plays a key role in the action of emerging anticancer therapies

The essential role of the MPL36 protein in leptospirosis

The impact of diabetes mellitus on morbidity and mortality in patients with COVID-19

New method allows the discovery of specific inhibitors of lactate transporter

New technology could revolutionize treatment for age-related macular degeneration

COVID-19 treatment: study evaluates ACEi and ARB effects on clinical outcomes

Researchers make breakthrough in fight against mucosal melanoma

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

Anti-inflammatory nanoparticles show promise in treating inflammatory bowel disease

New sensor may be deployed to screen patients for hard-to-diagnose cancers

Advancing vaccine adjuvants: exploring cutting-edge platforms for improved immunization

Trypsin and anaerobic bacteria boost SARS-CoV-2 Delta variant infectivity: oral hygiene key to prevention

Researchers discover new way to target bacterial cell wall

High body temperature may boost gut microbiota to fight viral infections

Study examines the antibacterial properties of cinnamon and eucalyptus essential oils compared with their isolated major compounds

Understanding the mechanisms behind rising antifungal drug resistance

Study reveals molecular mechanisms of H. pylori-induced gastric carcinogenesis

AI-based analysis method accelerates study of cell structures

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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