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Novel brain mechanism promises new and effective anesthetics

A brain mechanism involved in both dreaming and waking from sleep may hold the key to new, more effective anesthetics and stimulants, reported neuroscientists at the University of Arkansas for Medical Sciences (UAMS).

4 Jun 2010

Caltech biologists pinpoint molecular changes that help allow global spread of resistance to Tamiflu

Biologists at the California Institute of Technology have pinpointed molecular changes that helped allow the global spread of resistance to the antiviral medication Tamiflu (oseltamivir) among strains of the seasonal H1N1 flu virus.

4 Jun 2010

Three in five Americans may develop noise-induced hearing loss

Use of ear bud headphones by youngsters may save your ears from being assaulted by the noise of your teenagers' music or electronic game but are they damaging your child's hearing?

3 Jun 2010

Light therapy may be alternative treatment for prostate cancer

Cliff Berkman is working on a better way—one that specifically targets prostate cancer cells and causes a type of natural death that spares surrounding tissues from damage.

3 Jun 2010

Portland's Dana Gray and Jonathan Hill honored with AAPA's Physician-PA Partnership Award

Dana Gray, PA-C, of Portland, Ore., along with his physician partner, Jonathan Hill, MD, received the American Academy of Physician Assistants' 2010 Physician-PA Partnership Award at the organization's 38th Annual Physician Assistant Conference in Atlanta yesterday. The team has provided quality, broad-based trauma and cardiothoracic care to medically underserved populations in the Portland area for more than 15 years.

1 Jun 2010

Perspectives on computational methods applied to membrane proteins

There have been impressive advances in computational methods, allowing researchers to better understand biological and physiological systems at the atomic level. In its latest Perspectives in General Physiology series, the Journal of General Physiology (JGP) offers an in-depth look at several of these methods and the advantages of each as applied to membrane proteins, with special focus on ion channels.

1 Jun 2010

University of California scientists identify new kinase that regulates cell proliferation, migration

Scientists at the University of California, San Diego have identified a previously unknown kinase that regulates cell proliferation, shape and migration, and may play a major role in the progression or metastasis of cancer cells.

1 Jun 2010

Problems patients experience due to dental or skin conditions often misunderstood by care providers

Problems patients experience due to dental or skin conditions are often differently perceived by care providers. This is shown in a dissertation by Francesca Sampogna, a researcher in epidemiology at Istituto Dermopatico dell'Immacolata in Rome.

31 May 2010

RNA viruses hijack cellular enzyme to create viral replication factories on cell membranes

Nihal Altan-Bonnet, assistant professor of cell biology, Rutgers University in Newark, and her research team have made a significant new discovery about RNA viruses and how they replicate themselves.

29 May 2010

New, non-controversial source of stem cells can form heart muscle cells, repair heart damage

A new and non-controversial source of stem cells can form heart muscle cells and help repair heart damage, according to results of preliminary lab tests reported in Circulation Research: Journal of the American Heart Association.

29 May 2010

Scientists study interaction between Notch signaling pathway and BCL6 gene to understand how cancer forms

A Florida State University College of Medicine researcher has discovered a new interaction between a cell signaling system and a specific gene that may be the cause of B-cell lymphoma. The finding suggests a similar interaction could be occurring during the development of other types of cancer, leading to further understanding of how cancer works — and how it might be stopped.

28 May 2010

Research finding may offer future alternative to antibiotics

A team of scientists from government, academia and private industry has developed a novel treatment that protects mice from infection with the bacterium that causes tularemia, a highly infectious disease of rodents, sometimes transmitted to people, and also known as rabbit fever. In additional experiments with human immune cells, the treatment also demonstrated protection against three other types of disease-causing bacteria that, like the tularemia bacteria, occur naturally, can be highly virulent, and are considered possible agents of bioterrorism.

28 May 2010

Highlights from June 2010 issue of American Journal of Pathology

Dr. Kanneboyina Nagaraju and colleagues at the Children's National Medical Center, Washington, DC demonstrate that affected muscle may directly contribute to inflammation in muscular dystrophy. Their report can be found in the June 2010 issue of The American Journal of Pathology.

26 May 2010

Lytix Biopharma receives approval to initiate Phase I/IIa clinical trial of Lytixar for MRSA

The Norwegian pharmaceutical company Lytix Biopharma AS today announces the approval by the Swedish Medical Products Agency to commence a Phase I/IIa clinical trial with Lytixar (LTX-109) for nasal decolonisation of MRSA.

24 May 2010

Researchers discover key gene that promotes development of common kidney cancer

Researchers at Mayo Clinic's campus in Florida have discovered a key gene that, when turned off, promotes the development of common kidney cancer. Their findings suggest that a combination of agents now being tested in other cancers may turn the gene back on, providing a much-needed therapy for the difficult-to-treat cancer.

21 May 2010

Phase II study results of Lilly Oncology's tasisulam for metastatic melanoma to be presented at 46th ASCO

Lilly released results today from a Phase II study evaluating Lilly Oncology's tasisulam, a novel anti-cancer agent, in patients with metastatic melanoma, the deadliest form of skin cancer. Study results will be presented during the 46th Annual Meeting of the American Society of Clinical Oncology (ASCO) held in Chicago, Ill. on June 6, 2010.

21 May 2010

TAP to unveil innovative RAFT system at TERMIS Conference

The Automation Partnership, a world leader in the design and development of innovative automation for life science applications, is pleased to announce it will be unveiling RAFT (Real Architecture for 3D Tissue), its innovative system for generating reproducible, 3D collagen tissue constructs on TAP Stand 1 at the Tissue Engineering and Regenerative Medicine International Society Conference on June 13-17, in Galway, Ireland.

20 May 2010

Vanderbilt University orders Bruker's AVANCE III 900 US2 NMR spectrometer

Bruker, the leader in analytical magnetic resonance instrumentation, announces a major multi-systems NMR order from Vanderbilt University, including an ultra-high field AVANCE™ III 900 US2 NMR spectrometer. This purchase was made possible in large part by the American Recovery and Reinvestment Act. Vanderbilt will use these NMR instruments for a broad range of biophysical and structural analyses in biomedical research, as well as for cancer drug discovery using fragment-based approaches and structure-based drug design.

20 May 2010

Results from Phase 1 clinical trials of TRC105, TRC102, and TRC093 to be presented at ASCO 2010

TRACON Pharmaceuticals, a biotechnology company that develops targeted therapies for oncology and ophthalmology, announced today that results from Phase 1 clinical trials of TRC105, TRC102, and TRC093 will be presented at the annual meeting of the American Society of Clinical Oncology on June 5-7, 2010 in Chicago, IL.

19 May 2010

UNC-developed technique has broad applications in cancer, biomedical research

A precise understanding of cellular growth and movement is the key to developing new treatments for cancer and other disorders caused by dysfunctional cell behavior. Recent breakthroughs in genetic medicine have uncovered how genes control whether cellular proteins are turned 'on' or 'off' at the molecular level, but much remains to be understood about how protein signaling influences cell behavior.

17 May 2010

Membrane News and Research

Novel brain mechanism promises new and effective anesthetics

Caltech biologists pinpoint molecular changes that help allow global spread of resistance to Tamiflu

Three in five Americans may develop noise-induced hearing loss

Light therapy may be alternative treatment for prostate cancer

Portland's Dana Gray and Jonathan Hill honored with AAPA's Physician-PA Partnership Award

Perspectives on computational methods applied to membrane proteins

University of California scientists identify new kinase that regulates cell proliferation, migration

Problems patients experience due to dental or skin conditions often misunderstood by care providers

RNA viruses hijack cellular enzyme to create viral replication factories on cell membranes

New, non-controversial source of stem cells can form heart muscle cells, repair heart damage

Scientists study interaction between Notch signaling pathway and BCL6 gene to understand how cancer forms

Research finding may offer future alternative to antibiotics

Highlights from June 2010 issue of American Journal of Pathology

Lytix Biopharma receives approval to initiate Phase I/IIa clinical trial of Lytixar for MRSA

Researchers discover key gene that promotes development of common kidney cancer

Phase II study results of Lilly Oncology's tasisulam for metastatic melanoma to be presented at 46th ASCO

TAP to unveil innovative RAFT system at TERMIS Conference

Vanderbilt University orders Bruker's AVANCE III 900 US2 NMR spectrometer

Results from Phase 1 clinical trials of TRC105, TRC102, and TRC093 to be presented at ASCO 2010

UNC-developed technique has broad applications in cancer, biomedical research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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