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Study looks at brain damage that occurs after stroke

Brain damage that occurs even days after a stroke, increasing stroke size and devastation, is the focus of researchers trying to identify new treatments.

1 Jun 2007

Cartilage shield restores hearing in some otitis media infection patients

Inserting a “shield” of cartilage into the inner ear is a less invasive and more cost-effective alternative to membrane reconstruction when treating hearing loss in selected patients suffering from chronic middle ear infections (otitis media), according to a new study published in the June 2007 edition of Otolaryngology – Head and Neck Surgery .

1 Jun 2007

Designer lipid-like peptides to play a key role in improving drug delivery systems

Scientists from Institute of Biophysics and Nanosystems Research (IBN), Austrian Academy of Sciences and of Centre for Biomedical Engineering, Massachusetts Institute of Technology, Cambridge, USA report the study of Tuning Curvature and Stability of Monoolein Bilayers by Designer Lipid-Like Peptide Surfactants in the May 30th issue of the online, open-access journal PLoS ONE.

30 May 2007

Reversal of coma with an injection of glue

Neurosurgeons and neuroradiologists at Cedars-Sinai Medical Center injected a biosynthetic “glue” to seal off a spinal fluid leak and restore a comatose patient to consciousness.

28 May 2007

More evidence found indicating potassium channels play a critical role in sleep

A gene that controls the flow of potassium into cells is required to maintain normal sleep in fruit flies, according to researchers at the University of Wisconsin School of Medicine and Public Health (SMPH).

24 May 2007

Study revises dynamin's role in nerve cell function

An unexpected finding on how nerve cells signal to one another could rewrite the textbooks on neuroscience, says a collaborative team of researchers at Weill Cornell Medical College and Yale University.

17 May 2007

Model of proline dehydrogenase created

Researchers at the University of Missouri-Columbia recently created a model of proline dehydrogenase, an important cancer-preventing enzyme in the human body, and analyzed how it works.

17 May 2007

Potential therapeutic target for autoimmune vasculitis

A potential therapeutic target for autoimmune vasculitis has been identified by researchers of the Franz Volhard Clinic for Cardiovascular Diseases (FVK) of the Charity – University Medicine Berlin/HELIOS-Klinikum and the Max Delbruck Center for Molecular Medicine (MDC) Berlin-Buch.

16 May 2007

Researchers identify genetic markers associated with breast cancer tumor grade and lymph node metastases

Researchers have identified genetic markers on several chromosomes in the tissue surrounding tumor cells that are associated with breast cancer tumor grade and the presence of lymph node metastases, according to a study in the May 16 issue of JAMA.

16 May 2007

Researchers create agent that protects cells from the lethal effects of radiation

No drugs exist to protect the public from the high levels of radiation that could be released by a "dirty" bomb or nuclear explosion.

9 May 2007

BEMA Fentanyl demonstrates substantial transmucosal delivery

BioDelivery Sciences International, Inc. (Nasdaq:BDSI) announced the results of a 12 subject, crossover study comparing the absorption of fentanyl from both single and multiple BEMA? Fentanyl discs, as well as oral and intravenous doses of fentanyl.

8 May 2007

Elastic interactions of membrane proteins

Cellular survival relies crucially on the ability to receive and communicate signals from and to the outside world.

4 May 2007

Scientists work out mechanism underlying asymmetric cell division in nematode worms

When a cell divides, normally the result is two identical daughter cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells.

4 May 2007

New hope for patients with premature aging condition progeria

There is renewed hope for treatment of a rare genetic condition that causes rapidly accelerated aging and leads to an average life expectancy of 13 years.

4 May 2007

New way to target and potentially treat tumors

Research teams at Yale University and the University of Rhode Island have demonstrated a new way to target and potentially treat tumors using a short piece of protein that acts like a nanosyringe to deliver tags or therapy to cells, according to a report in the Proceedings of the National Academy of Sciences.

2 May 2007

Phenoxodiol, an investigational drug shows promise for ovarian cancer

A new study further supports the unique mechanism of action of phenoxodiol, an investigational drug being studied for the treatment of ovarian cancer.

2 May 2007

Scientists find new way to analyze the moving parts of large proteins

Scientists from Baylor College of Medicine (BCM) and Rice University have discovered a new way to analyze the moving parts of large proteins , a breakthrough that will make it easier for structural biologists to classify and scrutinize the active sites of proteins implicated in cancer and other diseases.

1 May 2007

Important step towards a spatially and temporally quantifiable model of the cell

Cell membranes are like two-dimensional fluids whose molecules are distributed evenly through lateral diffusion.

26 Apr 2007

Researchers find way to kill cystic fibrosis superbug, Burkholderia cenocepacia

Researchers from the Schulich School of Medicine & Dentistry at The University of Western Ontario , working with a group from Edinburgh, have discovered a way to kill the cystic fibrosis superbug, Burkholderia cenocepacia.

25 Apr 2007

Muscle restoration in an animal model of Duchenne muscular dystrophy

Using a new type of drug that targets a specific genetic defect, researchers at the University of Pennsylvania School of Medicine, along with colleagues at PTC Therapeutics Inc. and the University of Massachusetts Medical School, have for the first time demonstrated restoration of muscle function in a mouse model of Duchenne's muscular dystrophy (DMD).

24 Apr 2007