Meniere's Disease News and Research

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Meniere's disease is an abnormality of the inner ear causing a host of symptoms, including vertigo or severe dizziness, tinnitus or a roaring sound in the ears, fluctuating hearing loss, and the sensation of pressure or pain in the affected ear. The disorder usually affects only one ear and is a common cause of hearing loss. Named after French physician Prosper Ménière who first described the syndrome in 1861.

Scientists identify new genes associated with familial Meniere's disease

A team of scientists from the University of Granada (UGR) and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research—led by Pablo Roman-Naranjo and Jose Antonio López-Escámez, researcher in charge of the Biohealth Research Institute in Granada (ibs.GRANADA)—has identified new genes associated with familial Meniere's disease.

1 Dec 2021

Study links noise-induced inner ear nerve damage to endolymphatic hydrops

Exposure to loud noise, such as a firecracker or an ear-splitting concert, is the most common preventable cause of hearing loss. Research suggests that 12% or more of the world population is at risk for noise-induced loss of hearing.

11 Nov 2021

Novel technology reveals ear's inner secrets

What does it actually look like deep inside our ears? This has been very difficult to study as the inner ear is protected by the hardest bone in the body.

9 Apr 2020

New clinical practice guideline for Ménière's disease published

The Clinical Practice Guideline: Ménière's Disease in Otolaryngology-Head and Neck Surgery has been published today.

8 Apr 2020

Scientists provide clear picture of mysterious component of the inner ear

A few years ago, Ian Swinburne, HMS research fellow in systems biology, noticed something odd while conducting a time-lapse microscopy study of the inner ear of zebrafish. A tiny structure in the inner ear was pulsing like clockwork, inflating and deflating over and over.

29 Jun 2018

New research finds simple solution to minimize noise-induced hearing loss

It's well known that exposure to extremely loud noises -; whether it's an explosion, a firecracker or even a concert -; can lead to permanent hearing loss. But knowing how to treat noise-induced hearing loss, which affects about 15 percent of Americans, has largely remained a mystery.

8 May 2018

FDA permits Sound Pharmaceuticals to start SPI-1005 clinical trial for treatment of Meniere's Disease

Sound Pharmaceuticals is pleased to announce that it began enrolling a clinical trial to test SPI-1005 in the treatment of Meniere's Disease (MD). MD or idiopathic endolymphatic hydrops is an inner ear disease that involves episodic vertigo, sensorineural hearing loss, and tinnitus.

5 Jan 2016

Henry Ford launches clinical trial for treatment of tinnitus caused by noise trauma

Henry Ford Health System has launched a clinical trial to investigate a new drug for the treatment of tinnitus, a chronic ringing of the head or ears that affects more than 600 million people worldwide.

25 Jun 2014

Otonomy secures $49M in oversubscribed Series D round of financing

Otonomy, Inc., a biopharmaceutical company developing and commercializing innovative therapeutics for diseases and disorders of the inner and middle ear, today announced it has secured $49 million in an oversubscribed Series D round of financing.

30 Apr 2014

First patient enrolled in Otonomy's pivotal Phase 2b study of OTO-104 for Meniere's disease

Otonomy, Inc., a clinical stage biopharmaceutical company developing innovative therapeutics for diseases and disorders of the inner and middle ear, today announced enrollment of the first patient in its pivotal Phase 2b study of OTO-104 for the reduction of vertigo in patients with unilateral Meniere's disease.

11 Dec 2013

Researchers may have figured out ways to attack Meniere's disease

Researchers at University of Colorado School of Medicine may have figured out what causes Meniere's disease and how to attack it. According to Carol Foster, MD, from the department of otolaryngology and Robert Breeze, MD, a neurosurgeon, there is a strong association between Meniere's disease and conditions involving temporary low blood flow in the brain such as migraine headaches.

7 Dec 2013

New study tests vestibular prosthesis to help restore balance for people with Meniere's disease

Many disorders of the inner hear which affect both hearing and balance can be hugely debilitating and are currently largely incurable. Cochlear implants have been used for many years to replace lost hearing resulting from inner ear damage.

14 Jun 2013

Study explores views, beliefs about triggers of Meniere's disease symptoms

A report in one of the last issue of Psychotherapy and Psychosomatics addresses the physical and psychological triggers for attacks in Meniere's disease.

4 Apr 2013

AHRF to present free symposium on dizziness and balance disorders

The American Hearing Research Foundation will present a free, day-long educational symposium on dizziness and balance disorders on Saturday, April 6 at the Hilton Suites Chicago/Oakbrook in Oakbrook, Illinois.

27 Feb 2013

Otolaryngology-Head and Neck Surgery publishes new sudden hearing loss guideline

The first national treatment guideline for sudden hearing loss, a frightening condition that sends thousands in the U.S. to the emergency room each year, was published this month in the journal Otolaryngology-Head and Neck Surgery.

20 Mar 2012

Positive new data from Otonomy's OTO-104 Phase 1b study on Meniere's disease

Otonomy, Inc., a clinical stage biopharmaceutical company developing innovative therapeutics for diseases and disorders of the inner and middle ear, today announced that researchers presented positive new data from a Phase 1b study of the company's lead product candidate, OTO-104, in patients with Meniere's disease.

29 Sep 2011

Positive results from Otonomy's OTO-104 Phase 1b study in Meniere's disease

Otonomy, Inc., a clinical stage biopharmaceutical company developing innovative therapeutics for diseases and disorders of the inner and middle ear, today announced positive data from a Phase 1b study of the company's lead product candidate, OTO-104, in patients with Meniere's disease.

28 Apr 2011

Research on electrophysiological assessment of hearing in patients with acoustic neuromas

Manuel Don, Ph.D., is a principal investigator in the Division of Communication and Auditory Neuroscience at the House Ear Institute. Dr. Don joined the House Ear Institute in 1976 after working as an assistant research auditory physiologist at the University of California, Irvine.

17 Mar 2011

Endolymphatic sac shunt surgery improved hearing loss symptoms in flight attendant

When fluctuating hearing loss, with frequent bouts of nausea and vertigo caused New York flight attendant Patricia Gilbert to miss several work shifts, she sought answers from the medical community.

4 Mar 2011

New ear implant for Meniere’s disease

Meniere’s disease is a disease that affects the inner ear – a region responsible for balance. It affects 1% of Americans and can be quite disabling since it leads to attacks of vertigo. At present medications can not completely cure the condition and surgery is often unsuccessful.

24 Oct 2010