Metabolic Disease News and Research

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AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

AstraZeneca and FibroGen today announced that they have entered into a strategic collaboration to develop and commercialize FG-4592, a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease and end-stage renal disease.

31 Jul 2013

Obese fathers may pass their obesity to children and grandchildren

New research from the University of Adelaide shows that the sperm of obese fathers could increase the risk of both their children and their grandchildren to inherit obesity.

16 Jul 2013

Risk-factor screening of high-risk children may delay or prevent chronic health conditions later in life

Mexican American children are experiencing substantial burdens of obesity, pre-diabetes, and other health problems which historically would have been expected to develop much later in life. The findings of a new study by Texas Biomed scientists in San Antonio argue for early screening and intervention to delay or avoid chronic health problems as these children age.

12 Jul 2013

Study examines long-term effects on babies born to mothers with obstetric cholestasis

Babies born to mothers who suffer from a rare metabolic complication during pregnancy are programmed to be overweight, according to a study published today in the Journal of Clinical Investigation.

25 Jun 2013

Wayne State University awards $1.8 million for development of multidisciplinary research groups

Wayne State University's Office of the Vice President for Research today announced two research awards totaling $1.8 million in the Multidisciplinary Research Group Incubator Program (MRGIP), an internal funding program at the university.

21 Jun 2013

Study: Multiple islet autoantibodies in children indicate risk of developing type 1 diabetes

A decade-long JDRF-funded study led by the Institute of Diabetes Research in Helmholtz Zentrum M-nchen, Germany, is providing a deeper understanding of the link between autoantibodies and the risk of developing type 1 diabetes, highlighting the importance of pre-diabetes research into possible preventions for the disease.

20 Jun 2013

Research: Fetal exposure to BPA causes inflammation in fat tissues after birth

New research suggests that fetal exposure to the common environmental chemical bisphenol A, or BPA, causes increased inflammation in fat tissues after birth, which can lead to obesity and metabolic syndrome. Results of the animal study were presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

19 Jun 2013

Study: Male mice fed with high-fat diet are more likely to father offspring with higher levels of body fat

Male mice who were fed a high-fat diet and became obese were more likely to father offspring who also had higher levels of body fat, a new Ohio University study finds.

17 Jun 2013

NGM, MedImmune partner to develop novel therapeutics for treatment of diabetes and obesity

NGM Biopharmaceuticals, Inc. and MedImmune, the global biologics research and development arm of AstraZeneca, announced today that they have entered into an exclusive agreement to discover, develop and commercialize novel therapeutics from NGM's enteroendocrine cell program for the treatment of type 2 diabetes and obesity.

17 Jun 2013

Research reveals that men who experience RLS may have higher risk of dying earlier

Men who experience restless legs syndrome may have a higher risk of dying earlier, according to research that appears in the June 12, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

13 Jun 2013

Eight dairy organizations join to demonstrate tangible nutritional benefits of dairy

Eight dairy organizations from around the world are joining efforts to demonstrate the tangible nutritional benefits of dairy at a symposium on "Maintaining health with nutrient rich diets: The role of dairy in prevention of metabolic syndrome, cardiovascular disease (CVD), obesity and sarcopenia."

11 Jun 2013

Obesity in pregnancy can program kids to develop metabolic problems

Scientists in Sydney, Australia, have discovered that obesity and type 2 diabetes in pregnancy can program children to develop metabolic problems later in life. The good news is, this legacy is not set in stone-if children of obese mothers are careful about what they eat, it can be overturned.

11 Jun 2013

Research shows link between formula-feeding and higher risk for chronic diseases later in life

New evidence from research suggests that infants fed formula, rather than breast milk, experience metabolic stress that could play a part in the long-recognized link between formula-feeding and an increased risk of obesity, type 2 diabetes and other conditions in adult life.

6 Jun 2013

Omthera to be acquired by AstraZeneca

AstraZeneca today announced that it has entered into a definitive agreement to acquire Omthera Pharmaceuticals, a specialty pharmaceutical company based in Princeton, New Jersey, focused on the development and commercialization of new therapies for abnormal levels of lipids in the blood, referred to as dyslipidemia.

28 May 2013

HSPH researchers discover potential target to treat type 2 diabetes and other metabolic diseases

Harvard School of Public Health (HSPH) researchers have discovered that a particular type of protein (hormone) found in fat cells helps regulate how glucose (blood sugar) is controlled and metabolized (used for energy) in the liver.

8 May 2013

Researchers study influence of muscle types, body metabolism in diabetes

Researchers in the Life Sciences Institute at the University of Michigan have challenged a long-held belief that whitening of skeletal muscle in diabetes is harmful.

8 Apr 2013

Updated guidelines for metabolic and bariatric surgery

Significant new scientific evidence published over the last four years has prompted three major medical societies to change its guidance on who should get metabolic and bariatric surgery and which methods should be used.

6 Apr 2013

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Inflammation can be thought of as taking two major forms: acute or chronic. Acute inflammation, which can be painful, usually arises quickly and resolves quickly. It accompanies bacterial infections, traumatic injury and is useful to fight infections and promote healing.

28 Mar 2013

KineMed renews research collaboration with Pfizer for advancement of novel diabetes pathways

KineMed Inc. today announced the renewal of a non-exclusive research collaboration with Pfizer Inc. for the advancement of novel approaches towards metabolic disease, in particular Type II Diabetes.

From Pfizer, Inc. 28 Mar 2013

Research paper highlights implementation of infectious disease curriculum in Boston Public Schools

A research paper published online this month in Academic Medicine highlights the successful development, implementation, and effects of an infectious disease curriculum that has now been piloted in five Boston Public Schools.

27 Mar 2013