Metabolic Disease News and Research

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Scientists generate an atlas of human and mouse white adipocytes

Once considered to be inert, white adipose tissue is now recognized to be dynamic and to play an interactive role in a wide array of biological and metabolic processes.

18 Mar 2022

Socioeconomic deprivation is a risk factor for premature cardiovascular mortality, study suggests

People living in socially-deprived areas of the United States are more likely to die prematurely from cardiovascular (CV) complications according to new research published recently in Mayo Clinic Proceedings.

15 Mar 2022

Targeting regulation of subcellular architecture may hold opportunities to treat metabolic diseases

Cells use their molecular architecture to regulate their metabolic functions, and repairing diseased cells' architecture to a healthier state can also repair metabolism, according to a study led by Harvard T.H. Chan School of Public Health researchers.

10 Mar 2022

Anti-Müllerian hormone plays an active role in polycystic ovary syndrome

High levels of anti-Mullerian hormone (AMH) have traditionally been thought of as merely a passive byproduct of polycystic ovary syndrome (PCOS), but a new preclinical study by Weill Cornell Medicine researchers suggests that the hormone plays an active role in the disorder and may contribute to problems with ovulation and fertility.

10 Mar 2022

US research reveals the role of Heparan Sulfate in obesity

AMSBIO reports how researchers at the Washington University School of Medicine (St. Louis, USA) have used their 10E4 Heparan Sulfate (HS) antibody in pioneering obesity research to quantify the role of HS in the process of intercellular mitochondria transfer to macrophages.

From AMS Biotechnology 1 Mar 2022

Sleep apnea during pregnancy linked to the development of hypertension and metabolic syndrome

In a new study published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine, researchers examined whether sleep disordered breathing (primarily obstructive sleep apnea) during pregnancy and in the years after delivery is associated with an increased risk for hypertension and metabolic syndrome.

12 Feb 2022

Maternal metabolic syndrome can switch on imprinted gene associated with NAFLD in offspring

New research from North Carolina State University has found that an imprinted gene associated with development of non-alcoholic fatty liver disease (NAFLD) is switched on in mice who nurse from mothers with metabolic syndrome, even when those mice are not biologically related.

7 Feb 2022

Study reveals the beneficial role of fat in type 2 diabetes

With nearly 10% of the world's population affected, type 2 diabetes is a major public health issue. An excessively sedentary lifestyle and a too-caloric diet encourage the development of this metabolic disease by altering the functioning of pancreatic cells and making blood sugar regulation less effective.

11 Jan 2022

Drugs that block mineralocorticoid receptor may help protect bone cells during aging

Drugs we take like prednisone can weaken our bones and so can aging, and scientists working to prevent both have some of the first evidence that the best target may not be the logical one.

5 Jan 2022

Promising new drug target for TB identified

Mycobacterium tuberculosis (Mtb), the hardy bacterial species that causes tuberculosis (TB), has an unexpected vulnerability that future drugs may be able to exploit, according to a study from researchers at Weill Cornell Medicine.

21 Dec 2021

Newly discovered hormone may play a key role in the development of type 1 and type 2 diabetes

A newly discovered hormone named fabkin helps regulate metabolism and may play an important role in the development of both type 1 and type 2 diabetes, according to research led by the Sabri Ülker Center for Metabolic Research at Harvard T.H. Chan School of Public Health.

12 Dec 2021

New hormone may play a key role in the development of type 1 and type 2 diabetes

8 Dec 2021

Physical activity may prevent accumulation of metabolic risk factors in menopausal women

A study conducted at the University of Jyväskylä in the Faculty of Sport and Health Sciences shows that menopausal transition is associated with unfavourable changes in metabolic health that may be mitigated with a physically active lifestyle. Especially, physical activity alleviated the increase in systolic blood pressure.

25 Nov 2021

New technique may be a significant leap forward in the understanding of human cells

Most human diseases can be traced to malfunctioning parts of a cell — a tumor is able to grow because a gene wasn't accurately translated into a particular protein or a metabolic disease arises because mitochondria aren't firing properly, for example. But to understand what parts of a cell can go wrong in a disease, scientists first need to have a complete list of parts.

24 Nov 2021

Clearing old, dysfunctional cells in fat alleviates diabetes

Eliminating old, dysfunctional cells in human fat also alleviates signs of diabetes, researchers from UConn Health report. The discovery could lead to new treatments for Type 2 diabetes and other metabolic diseases.

22 Nov 2021

Study involving a rat model offers potential treatment for Alexander disease

Alexander disease is a progressive and rare neurological disorder with no cure or standard course of treatment. But a new study led by researchers at the University of Wisconsin–Madison involving a rat model of the disease offers a potential treatment for the typically fatal condition.

18 Nov 2021

Lifestyle habits play a key role in predicting the risk of metabolic syndrome in non-obese individuals

Researchers from Japan have found that lifestyle habits play an important role in predicting the risk of developing metabolic syndrome in non-obese individuals, not only obese individuals.

18 Nov 2021

Racial or ethnic group of patients with diabetes influences prognosis of the disease

Professor and researcher of the Faculty of Nursing and Podiatry of the UV, Yasmín Ezzatvar, together with researchers from other centers, concludes that the racial or ethnic group of patients with type 1 and 2 diabetes mellitus influences the prognosis of the disease, due to differences in mortality, risk of kidney disease or risk of cardiovascular disease.

15 Nov 2021

Researchers discover new gene critical for daily behavioral rhythms

Life is organized on a 24-hour schedule. Central to this regular rhythm is the circadian clock, timekeepers that are present in virtually every organ, tissue and cell type. When a clock goes awry, sleep disruption or a variety of diseases can result.