Metabolic Disease News and Research

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Simple juice concentrate from the Japanese plum may reduce cardiovascular disease risk

More than 122 million Americans – about half of the U.S. population ages 20 and older – have high blood pressure, referred to medically as hypertension.

13 Jun 2023

How does tirzepatide stimulate insulin secretion?

Tirzepatide, a drug approved for diabetes and on the fast track for approval as a weight loss therapy, works through a unique ability to activate two different mechanisms the body uses to control insulin secretion and energy balance, Duke Health researchers report.

6 Jun 2023

Groundbreaking 3D imaging unveils secrets of cilia

Study provides a comprehensive analysis of human primary cilia, uncovering their architectural features and functional implications in cellular processes. It highlights the importance of these sensory organelles in signaling, motility, and intercellular communication.

31 May 2023

Important discovery could lead to new treatments for obesity and related diseases

Researchers at the University of East Anglia and the University of Cambridge have made an important discovery in the race to find treatments for obesity and related diseases, such as diabetes.

31 May 2023

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Melatonin, a hormone derived from the pineal gland, has diverse effects on cellular processes. This review explores its potential role as an epigenetic regulator, particularly in modulating DNA methylation, and suggests its use in combination therapy as a novel anticancer strategy.

30 May 2023

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses.

19 May 2023

Is there an association between long-term plasma caffeine intake and adiposity, type 2 diabetes, and cardiovascular diseases?

Investigate the effects of long-term exposure to higher plasma caffeine concentrations on T2D, adiposity, and cardiovascular diseases.

18 May 2023

Change in liver clock could affect synchronization of the circadian cycle

Organisms rely on a biological clock known as the 'circadian' clock to regulate their activity according to the time of day.

17 May 2023

Experts urge increased attention to the threat of climate change and pollution on children's health

Study explores the impact of climate change and environmental chemicals on children's health.

9 May 2023

Is there an association between physical activity, sedentary behavior, and sleep with well-being in older adults?

Researchers described 24-hour behaviors and their relationship with mental well-being in older adults.

3 May 2023

Non-optimal temperatures contribute to cardiovascular disease burden across the globe

A new study by physician-scientists at University Hospitals Harrington Heart & Vascular Institute has shown that non-optimal temperatures have a significant impact on the cardiovascular disease (CVD) burden across the globe.

3 May 2023

Arterial stiffness may be a novel risk factor for childhood and adolescent metabolic disease

Arterial stiffness may be a novel risk factor for metabolic syndrome in teens, a paper published in the American Journal of Physiology-Heart and Circulatory Physiology concludes. The study was conducted in collaboration between the University of Bristol in the UK, the University of Exeter in the UK, and the University of Eastern Finland.

26 Apr 2023

Research reveals molecular features of rare mtDNA mutations

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

13 Apr 2023

Study sheds light on cardiovascular health of babies exposed to opioids in the womb

A new study sheds light on an understudied aspect of today's opioid crisis: What happens to the cardiovascular health of babies exposed to opioids in the womb.

13 Apr 2023

Obstructive sleep apnea can cause early cognitive decline even in patients without co-morbidities

Obstructive sleep apnea (OSA) is a potentially dangerous condition. During sleep, the throat muscles of people with OSA relax and block the airflow into the lungs, so that they repeatedly stop breathing.

6 Apr 2023

Collaboration between family doctors and periodontists essential for effective management of systemic health conditions

Close collaboration between family doctors and periodontists and other oral health professionals is necessary for an effective prevention, early detection and management of widespread systemic health conditions, affecting millions of patients everywhere.

28 Mar 2023

Public’s view of obesity has changed since the pandemic, survey shows

Nearly a third of Americans (29%) say COVID-19 made them more worried than ever about having obesity prompting about 28 million people to consider weight-loss methods they hadn't thought about before the pandemic began, including nearly 6.4 million thought about turning to either weight-loss surgery or taking prescription anti-obesity drugs for the first time, according to a new survey whose findings were published online in the peer-reviewed journal, Surgery for Obesity and Related Diseases.

22 Mar 2023