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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

New study unpacks the hidden power of breastfeeding

Breastfeeding, even partially alongside formula feeding, changes the chemical makeup-;or metabolome-;of an infant's gut in ways that positively influence brain development and may boost test scores years later, suggests new CU Boulder research.

13 Dec 2023

Is maternal cannabis exposure associated with increased risk of adverse pregnancy outcomes related to placental function?

Researchers assessed the relationship between maternal cannabis use and adverse pregnancy outcomes linked to placental function.

13 Dec 2023

Small molecule applications of process Raman spectroscopy

In this interview, Kevin Broadbelt of Thermo Fisher Scientific discusses the small molecule applications of process Raman spectroscopy.

From Thermo Fisher Scientific – Portable and Handheld Raman Spectroscopy 11 Dec 2023

Novel stem cell treatment could revolutionize liver disease management

Mortality related to end stage liver disease is ranked as the 12th most common cause of death in the U.S. Liver transplantation remains the only treatment for end stage liver disease, but there is a critical shortage of organ donors, necessitating a dire need for new forms of treatment.

7 Dec 2023

Optibrium’s Quantum Mechanics and Machine Learning Methods Predict Routes of Drug Metabolism

Peer-reviewed study published in Xenobiotica describes an innovative new method that predicts the routes and products of Phase I and II metabolism with high sensitivity and greater precision than other approaches.

From Optibrium Ltd. 7 Dec 2023

Link between gut dysbiosis and chronic diseases explored in new study

Study explores the ecological causes of gut dysbiosis and its link to human diseases, revealing how imbalances in gut microbiota composition, influenced by host-derived factors like oxygen and nitrate, contribute to various chronic conditions.

5 Dec 2023

New biomarker for inflammatory bowel disease identified through reverse metabolomics

In recent years, microbiome research has started to shift its focus from the microbes themselves to the molecules they produce.

5 Dec 2023

Study reveals how maternal diabetes affects birth defects at the single-cell level

The mechanisms by which maternal diabetes mellitus contributes to congenital abnormalities in the fetus.

4 Dec 2023

Study suggests a complex metabolic basis between alcohol consumption and CVD

A new study identified 60 alcohol-associated circulating metabolites, which appear to produce counteractive effects on the risk of heart disease.

27 Nov 2023

The potential of polyunsaturated fatty acids in alleviating depression and reducing suicide risk

Research in 'Molecular Psychiatry' explores the role of long-chain polyunsaturated fatty acids (LC-PUFAs) in major depressive disorder (MDD) and suicide risk, showing mixed results in clinical trials for depression treatment. The study underscores the need for further investigation into LC-PUFAs' neurobiology to advance personalized medicine for mood disorders and suicide prevention.

26 Nov 2023

Statins may reduce breast cancer mortality rates

The relationship between serological cholesterol levels, statin usage, and breast cancer (BC) mortality.

21 Nov 2023

New study highlights urgent need for specific biomarkers in vascular cognitive impairment and dementia diagnosis

A review in Nature Reviews Neurology discusses the pathophysiological processes in vascular cognitive impairment and dementia (VCID), emphasizing the need for specific biomarkers to differentiate VCID from Alzheimer's disease and to improve diagnosis and treatment strategies, moving beyond reliance on neuroimaging and patient histories.

15 Nov 2023

Revolutionizing critical care: the potential of gut microbiota therapeutics

The curative potential and limitations of gut microbiome-based therapeutics in critical illnesses.

13 Nov 2023

Broccoli sprouts diet protects mice from Crohn's disease, study shows

High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD), according to a study conducted in mice.

9 Nov 2023

Avocado a day may keep diabetes at bay, suggests nutritional biomarker study

New research in The Journal of Nutrition links avocado consumption with lower diabetes risk, revealing specific metabolomic biomarkers that indicate potential for reduced fasting glucose and insulin levels.

5 Nov 2023

Advances in grain research illuminate potential for precision nutrition in clinical settings

Grains are a primary source of energy (calories) in the diet.

1 Nov 2023

Research reveals both protective and harmful gut microbiota associated with sleep apnea risk

The causal relationship between gut microbiota, associated metabolites, and obstructive sleep apnea (OSA).

30 Oct 2023

Can metabolic biomarkers help distinguish between depressive episodes of bipolar disorder and major depressive disorder?

Researchers identify metabolomic biomarkers from dried blood spots that can distinguish between depressive episodes in major depressive disorder and bipolar disorder. The study enhances diagnostic accuracy, particularly when traditional psychiatric assessments are inconclusive.

26 Oct 2023

Exploring the link between red meat intake and inflammation

Inflammation is a risk factor for many chronic diseases, including cardiovascular disease (CVD), and the impact of diet on inflammation is an area of growing scientific interest.