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Study reveals mechanisms behind sensitivity of multiple myeloma cells to EZH2 inhibition

Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma.

13 Feb 2021

Metabolomics and machine learning used to identify possible COVID-19 biomarkers

One of the many mysteries still surrounding COVID-19 is why some people experience only mild, flu-like symptoms, whereas others suffer life-threatening respiratory problems, vascular dysfunction and tissue damage.

10 Feb 2021

Modified lipids target the body’s endocannabinoid system to regulate pain and inflammation

When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, researchers report.

10 Feb 2021

BMI, male sex, smoking, depression and metabolic syndrome contribute to biological aging

A 'biological age' score predicts that being male, overweight, a smoker and having depression all contribute to biological aging, a study published today in eLife reports.

9 Feb 2021

Metal-containing radiopharmaceuticals could improve access to diagnostic imaging of AD

A team of researchers from the Laboratory of Biophysics at NUST MISIS, Lomonosov Moscow State University and D. Mendeleev University of Chemical Technology of Russia has summarized metal-containing diagnostic agents for positron emission tomography (PET), magnetic resonance imaging (MRI), and single-photon emission computed tomography (SPECT) imaging of Alzheimer's disease (AD).

9 Feb 2021

Challenges of Cannabis Analysis and Impacts on Driving and Public Health

An interview with Madeleine Swortwood of Sam Houston State University, on the symposia she will give at Pittcon 2022 about the analytical challenges of cannabis and its impacts on driving and public health.

From Pittcon 9 Feb 2021

New wearable sensor uses nanomaterials technology to detect illegal drugs in sweat

Researchers in South Korea have successfully developed a wearable sensor that can detect illegal drugs in sweat by using nanomaterials technology that amplify the optical signal of narcotics to a flexible, body-worn material.

8 Feb 2021

Scientists receive award to explore how diet and metabolism influence the immune system

A pair of scientists from Van Andel Institute and the National Institute of Allergy and Infectious Diseases have been granted a three-year, $1.5 million Allen Distinguished Investigator award from The Paul G. Allen Frontiers Group, a division of the Allen Institute, to better understand how diet and metabolism influence the immune system's ability to fight off threats such as infections.

3 Feb 2021

Evolutionary history reveals the function of fish and human bitter receptors

To evaluate the chemical composition of food from a physiological point of view, it is important to know the functions of the receptors that interact with food ingredients.

2 Feb 2021

Study examines the link between walnut metabolites and risk of cardiometabolic diseases

Researchers, from the Harvard T.H. Chan School of Public Health in collaboration with investigators from Rovira i Virgili University and the University of Navarra, Spain, used machine learning models, a subset of artificial intelligence, to identify more precisely the components in walnuts that may be responsible for potentially reducing the risk of type 2 diabetes and cardiovascular diseases - two of the leading causes of death in the U.S.

2 Feb 2021

Thread-based sensors can measure head movements in real time

Engineers at Tufts University have created and demonstrated flexible thread-based sensors that can measure movement of the neck, providing data on the direction, angle of rotation and degree of displacement of the head.

29 Jan 2021

Biliverdin shields SARS-CoV-2 from host antibody response, study finds

A team of international scientists has recently revealed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with two heme metabolites, bilirubin and biliverdin, to escape the antibody-mediated host immune responses.

27 Jan 2021

Probiotics as adjuvant therapy for COVID-19 patients

In a recent review published in the Journal of Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Luigi Santacroce and Francesco Inchingolo et al. address the many factors such as dysbiosis (imbalance in the microbiota) that could influence the SARS-CoV-2 infection course.

25 Jan 2021

ACE2 and furin levels linked to inflammation in smokers with COVID-19

A new study reports the level of ACE2 and furin, two enzymes that are intimately linked to infection with SARS-CoV-2, the causative agent of COVID-19.

21 Jan 2021

Researchers discover potent antifungal agent from attine ant farms

Attine ants are farmers, and they grow fungus as food. Pseudonocardia and Streptomyces bacteria are their farmhands, producing metabolites that protect the crop from pathogens.

20 Jan 2021

Can metabolic biomarkers help clinicians stratify adverse outcome risk in COVID-19 patients?

A recent study describes the alterations in lipids and other parameters that define the state of dysfunctional metabolism in acute COVID-19 illness.

20 Jan 2021

Fecal microbiome and metabolome vary in healthy and food-allergic twins, shows study

A new study out of the University of Chicago and Stanford University on pairs of twins with and without food allergies has identified potential microbial players in this condition.

19 Jan 2021

Study: Oligodendrocytes play key role in the distribution of energy-rich molecules

The human brain has about as many neurons as glial cells. These are divided into four major groups: the microglia, the astrocytes, the NG2 glial cells, and the oligodendrocytes.

19 Jan 2021

New method could provide additional insight into brain tumors

A look at RNA tells us what our genes are telling our cells to do, and scientists say looking directly at the RNA of brain tumor cells appears to provide objective, efficient evidence to better classify a tumor and the most effective treatments.

19 Jan 2021

Mothers of children with autism have many significantly different metabolite levels, study finds

Now, a study by researchers at the Rensselaer Polytechnic Institute, Arizona State University, and the Mayo Clinic found that mothers of children with autism spectrum disorder had several marked different metabolite levels two to five years after they gave birth compared to mothers of normally developing children.

17 Jan 2021

Metabolites News and Research

Study reveals mechanisms behind sensitivity of multiple myeloma cells to EZH2 inhibition

Metabolomics and machine learning used to identify possible COVID-19 biomarkers

Modified lipids target the body’s endocannabinoid system to regulate pain and inflammation

BMI, male sex, smoking, depression and metabolic syndrome contribute to biological aging

Metal-containing radiopharmaceuticals could improve access to diagnostic imaging of AD

Challenges of Cannabis Analysis and Impacts on Driving and Public Health

New wearable sensor uses nanomaterials technology to detect illegal drugs in sweat

Scientists receive award to explore how diet and metabolism influence the immune system

Evolutionary history reveals the function of fish and human bitter receptors

Study examines the link between walnut metabolites and risk of cardiometabolic diseases

Thread-based sensors can measure head movements in real time

Biliverdin shields SARS-CoV-2 from host antibody response, study finds

Probiotics as adjuvant therapy for COVID-19 patients

ACE2 and furin levels linked to inflammation in smokers with COVID-19

Researchers discover potent antifungal agent from attine ant farms

Can metabolic biomarkers help clinicians stratify adverse outcome risk in COVID-19 patients?

Fecal microbiome and metabolome vary in healthy and food-allergic twins, shows study

Study: Oligodendrocytes play key role in the distribution of energy-rich molecules

New method could provide additional insight into brain tumors

Mothers of children with autism have many significantly different metabolite levels, study finds

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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