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Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

The survival of patients with pediatric acute lymphoblastic leukemia (ALL) has significantly improved in the last several decades. However, novel strategies to identify cases that are likely to respond poorly to treatment are still needed.

24 Oct 2019

McMaster University research potentially offers new tool for assessing eating habits

Researchers at McMaster University have identified several chemical signatures, detectable in blood and urine, that can accurately measure dietary intake, potentially offering a new tool for physicians, dieticians and researchers to assess eating habits, measure the value of fad diets and develop health policies.

24 Oct 2019

Molecular processes underlying communication between gut microbes and brain cells revealed

New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time by scientists at Weill Cornell Medicine and Cornell's Ithaca campus.

23 Oct 2019

Research suggests greater complexity in cellular protein movement

A new imaging technique that makes it possible to match motor proteins with the cargo they carry within a cell is upending a standard view of how cellular traffic reaches the correct destination.

23 Oct 2019

Healthiest gut bacteria with plant-based or Mediterranean diet

A new study shows that specific foods that are supplied by either a plant-based or a Mediterranean-type diet can protect the gut against inflammatory disorders, by selectively promoting the growth of anti-inflammatory bacteria.

21 Oct 2019

New blood self-collection device quickly estimates a person's exposure to radiation

A University of Arizona College of Medicine - Phoenix research team has developed a blood self-collection device to quickly estimate a person's exposure to radiation in the event of a nuclear accident or attack.

16 Oct 2019

Young blood may hold the key to treating age-related diseases

In what sounds like a scene from a science fiction movie, researchers in 2005 stitched together old and young mice so they shared a circulatory system.

16 Oct 2019

Subtle changes in mitochondrial DNA can have profound consequences for patient's health

Subtle changes in the DNA of mitochondria, the tiny power plants within cells, can have profound consequences for a patient's health.

16 Oct 2019

The language of metabolites can be decoded with new genome technology

A team of microbiologists and genomicists has invented a genetic engineering tool that advances the study of secondary metabolites, which will expand our understanding of how microbes evolve.

14 Oct 2019

Chemists employ new strategy to synthesize complex natural products

Chemists from the University of Basel have succeeded in synthesizing two complex natural products from the group of dithiodiketopiperazines (DTPs).

9 Oct 2019

Chemists successfully synthesize complex natural products

Chemists from the University of Basel have succeeded in synthesizing two complex natural products from the group of dithiodiketopiperazines (DTPs). For this, they employed a new strategy based on "C-H bond activation," resulting in a short and high yielding route.

9 Oct 2019

Salford scientists identify new drug candidate to starve and suffocate breast cancer stem cells

Scientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for new therapies to treat breast cancer patients.

8 Oct 2019

UC Davis engineers develop new test to detect opioid drugs in exhaled breath

A test to detect opioid drugs in exhaled breath has been developed by engineers and physicians at the University of California, Davis. A breath test could be useful in caring for chronic pain patients as well as for checking for illegal drug use.

4 Oct 2019

Gut microbiome changes with cooking of plant foods, says new study

UC San Francisco and Harvard have found that profound changes occur in the human gut microbiome depending on whether plant food is consumed raw or cooked.

1 Oct 2019

NAU researchers aim to find microbial link between two common respiratory diseases

Asthma and chronic rhinosinusitis- sinus inflammation that lasts for at least three months- are serious and costly diseases, and both are on the rise. According to the American Academy of Allergy, Asthma and Immunology, CRS affects up to 16 percent of the U.S. adult population and eats up a staggering 5 percent of the country's health care budget each year.

27 Sep 2019

Metabolite may predict cancer versus autism risk in PTEN patients

In a new study published in American Journal of Human Genetics, a team of researchers led by Charis Eng, M.D., Ph.D., Chair of Cleveland Clinic's Genomic Medicine Institute, identified a metabolite that may predict whether individuals with PTEN mutations will develop cancer or autism spectrum disorder.

26 Sep 2019

Metabolic imbalance in cancer patients associated with resistance to immune checkpoint blocker

A metabolic imbalance in some cancer patients following treatment with a checkpoint inhibitor drug, nivolumab, is associated with resistance to the immunotherapy agent and shorter survival, report scientists from Dana-Farber Cancer Institute, in collaborative work with the Broad Institute of MIT and Harvard.

25 Sep 2019

New study can benefit children facing developmental challenges

In a first-of-its-kind study, Children's Hospital Los Angeles researchers piece together a road map of typical brain development in children during a critical window of maturation.

25 Sep 2019

Study: Toxocara roundworm infection is accompanied by complex molecular signaling cascade

Neurotoxocarosis (NT) occurs in humans when larvae of the Toxocara roundworm migrate into the central nervous system. That infection is accompanied by a complex molecular signaling cascade, including changes to anti-inflammatory lipid molecules, researchers now report in PLOS Neglected Tropical Diseases.

From PLOS ONE 25 Sep 2019

Hormone therapy decreases metabolites directly linked with Type 2 diabetes

The Women's Health Initiative remains one of the most highly quoted when debating the benefits and risks of hormone therapy.

24 Sep 2019

Metabolites News and Research

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

McMaster University research potentially offers new tool for assessing eating habits

Molecular processes underlying communication between gut microbes and brain cells revealed

Research suggests greater complexity in cellular protein movement

Healthiest gut bacteria with plant-based or Mediterranean diet

New blood self-collection device quickly estimates a person's exposure to radiation

Young blood may hold the key to treating age-related diseases

Subtle changes in mitochondrial DNA can have profound consequences for patient's health

The language of metabolites can be decoded with new genome technology

Chemists employ new strategy to synthesize complex natural products

Chemists successfully synthesize complex natural products

Salford scientists identify new drug candidate to starve and suffocate breast cancer stem cells

UC Davis engineers develop new test to detect opioid drugs in exhaled breath

Gut microbiome changes with cooking of plant foods, says new study

NAU researchers aim to find microbial link between two common respiratory diseases

Metabolite may predict cancer versus autism risk in PTEN patients

Metabolic imbalance in cancer patients associated with resistance to immune checkpoint blocker

New study can benefit children facing developmental challenges

Study: Toxocara roundworm infection is accompanied by complex molecular signaling cascade

Hormone therapy decreases metabolites directly linked with Type 2 diabetes

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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